Fatty acid biosynthesis (Drosophila melanogaster)

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Acetoacetyl-ACPtrans-delta2-enoyl-CoA3-L-Hydroxyacyl-CoA3-ketoacyl-CoAButyryl-ACPAcetyl-ACPAcyl-CoA (n+2)Long-Chain fatty acidTCA CycleOxaloacetateCitrateHOMOLOGY MAPP6 iterationsPalmitateMitochondrionAcetyl-synthaseFatty acyl CoACrotonoyl-ACPMalonyl-ACPSee Triacylglyceride Synthesis MAPPAcetyl-CoAbeta-hydroxybutyrylless than 6 iterationsCytosolPyruvatePalmitoyl-ACPMalonyl-CoA1ECHDC1HADHSCECHDC2ACSL5AcCoASCG3523yip2DECR1CG11198l(2)44DEaACSL6ACACBCG6543CG3523SCDCG16935CG3523CG3523CG9577CG1516CG3961CG3523CG3523PECRCG3523CG3523ATPCLACSL4CG6984


Description

No description

Comments

GenMAPP notes 
Updated from original (Kam Dahlquist) by Magali Jaillard, Marijke Vermeer, Michiel Adrieans, Ron Schormans and Chris Evelo
GenMAPP remarks 
http://www.bigcat.unimaas.nl/mapps/

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Quality Tags

Ontology Terms

 

Bibliography

  1. de Renobales M, Blomquist GJ; ''Biosynthesis of medium chain fatty acids in Drosophila melanogaster.''; Arch Biochem Biophys, 1984 PubMed Europe PMC Scholia
  2. Keith AD; ''Fatty acid metabolism in Drosophila melanogaster: interaction between dietary fatty acids and de novo synthesis.''; Comp Biochem Physiol, 1967 PubMed Europe PMC Scholia
  3. Parvy JP, Napal L, Rubin T, Poidevin M, Perrin L, Wicker-Thomas C, Montagne J; ''Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system.''; PLoS Genet, 2012 PubMed Europe PMC Scholia
  4. Lowe PN, Rhodes S; ''Purification and characterization of [acyl-carrier-protein] acetyltransferase from Escherichia coli.''; Biochem J, 1988 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
125349view19:46, 3 February 2023AlexanderPicoremoved old genmapp comments
125348view19:44, 3 February 2023AlexanderPicoModified description
116920view09:39, 16 May 2021EweitzModified title
114463view09:40, 13 January 2021Finterlysmall graphical updates. add link to pathway and biological type to metabolites.
109411view18:26, 16 March 2020L DupuisConverted interactions to graphical lines
107101view14:18, 17 September 2019MaintBotChEBI identifier normalization
106093view12:00, 16 August 2019MaintBotHMDB identifier normalization
93103view16:14, 28 July 2017DeSlChanges pubchem substance ID to chebi
86163view08:36, 3 July 2016EgonwColored metabolites by customs and connected more lines.
84333view09:13, 6 February 2016EgonwFixed data sources of KEGG Compound IDs.
77439view20:27, 8 September 2014MaintBotremoved old homology label
73954view20:33, 10 March 2014EgonwMarked three metabolite like structures as type metabolite.
73678view08:19, 15 February 2014EgonwAdded a few metabolite identifiers.
73400view20:18, 26 January 2014EgonwMarked 'long chain fatty acid' as Metabolite, so that the link out will work.
73323view12:18, 20 January 2014AndraAdded references
73322view12:11, 20 January 2014AndraPeriodical save, work in progress
73321view12:01, 20 January 2014AndraPeriodical save, work in progress
73320view11:51, 20 January 2014AndraPeriodical save, work in progress
73319view11:40, 20 January 2014AndraPeriodical save, work in progress
73318view11:30, 20 January 2014AndraPeriodical save, work in progress
73317view11:09, 20 January 2014MaintBotupdated curation tag
73236view21:17, 12 January 2014EgonwAdded a few metabolite identifiers.
73235view21:14, 12 January 2014EgonwConverted metabolite Label's into DataNode's.
71545view19:25, 17 October 2013MaintBotAutomated update of data sources
68709view21:35, 6 July 2013MaintBotUpdated to 2013 gpml schema
67242view10:25, 26 June 2013Christine ChichesterOntology Term : 'fatty acid biosynthetic pathway' added !
40877view22:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
34155view21:07, 9 December 2009MaintBotAutomatic update of empty xrefs
21876view11:32, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:WP568]]: Moved to stable identifier
8606view14:04, 7 January 2008MaintBotAdded to category $category
19459view14:04, 7 January 2008EveloUploaded new pathway
8604view14:04, 7 January 2008KdahlquistUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
3-L-Hydroxyacyl-CoA
3-ketoacyl-CoA
ACACBGeneProduct
ACSL4GeneProduct
ACSL5GeneProduct
ACSL6GeneProduct
ATPCLGeneProduct36760 (Entrez Gene)
AcCoASGeneProduct40348 (Entrez Gene)
Acetoacetyl-ACPMetabolite2393 (ChEBI)
Acetyl-ACPMetaboliteC03939 (PubChem-compound)
Acetyl-CoAMetabolite392413 (Chemspider)
Acetyl-synthase
Acyl-CoA (n+2)
Butyryl-ACPMetabolite8040 (PubChem-substance)
CG11198GeneProduct35761 (Entrez Gene)
CG1516GeneProduct36020 (Entrez Gene)
CG16935GeneProduct36540 (Entrez Gene)
CG3523GeneProduct33524 (Entrez Gene)
CG3961GeneProduct40056 (Entrez Gene)
CG6543GeneProduct36536 (Entrez Gene)
CG6984GeneProduct36926 (Entrez Gene)
CG9577GeneProduct33016 (Entrez Gene)
CitrateMetabolite29081 (Chemspider)
Crotonoyl-ACP
DECR1GeneProduct
ECHDC1GeneProduct
ECHDC2GeneProduct
Fatty acyl CoA
HADHSCGeneProduct
Long-Chain fatty acidCHEBI:15904 (ChEBI)
Malonyl-ACPMetaboliteC01209 (PubChem-substance)
Malonyl-CoAMetaboliteHMDB01175 (HMDB)
OxaloacetateMetabolite2509917 (Chemspider)
PECRGeneProduct
Palmitate440215 (Chemspider)
Palmitoyl-ACP
PyruvateMetabolite96901 (Chemspider)
SCDGeneProduct252579 (Entrez Gene)
beta-hydroxybutyrylMetabolite644065 (PubChem-compound)
l(2)44DEaGeneProduct46068 (Entrez Gene)
trans-delta2-enoyl-CoA
yip2GeneProduct34313 (Entrez Gene)

Annotated Interactions

No annotated interactions
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