TGF-beta receptor signaling pathway (Mus musculus)

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MTNUGolgi apparatusControlENActivationNUNucleusProteolytic cleavageCYCYAutophosphorylationMolecule in the pathwayNUGOAcetylationEnzyme complexInhibitionSumoylationCYCYCYNUDesumoylationECNUNU -> CYNUNUPalmitoylationCYNUGlycosylationEndoplasmic reticulumCytoplasmNUCYNUNU(Protein-protein interaction)NUNUCYCYNUERCYCYEndosomeCYNUMitochondriaMethylationCYCYLigandReaction through unknown mechanisms/moleculesNUNUTranslocationCYCYNUNU -> CYCYNUNUNUExtracellularDeacetylationGlycosylationCYNUCYCYAccession Number: NetPath 7; cellmap:7DeubiquitinationCYCYCYRecruitmentNUNUDPlasma membraneNUCYMolecular associationUbiquitinationNUPMReceptorCYDemethylationNUCYCYDephosphorylationProteins in a complex interactionPhosphorylationFosbTgfb1E2f4PrkcdTgfb3Mapk14Map3k7E2f4Tgfb3Ctnnb1Prkcb1BtrcSkiSmad3Mapk8Nup153Tgfbr1Tgfbr1Pias1Camk2gDaxxFoxo3aMycSdc2Pias2Smad7Anapc1Tgfbr2Dcp1aRbl2Cul1Tgfbr2Cdc16Smurf2Smad7JunEts1Lef1Smad4Smad2TgifCdc16Map2k6E2f4Rock1Skp1aTgfbr3Hspa8Cdc27Rb1Tgfbr2Gene 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


Description

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Comments

GenMAPP notes 
NetPath 7; cellmap:7 - TGF-beta Receptor Signaling Pathway

The TGF-beta Receptor Signaling pathway was kindly reviewed by Van Le Hong, Wei He and other members of Joan Massague’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.

GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org

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Bibliography

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History

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CompareRevisionActionTimeUserComment
118015view11:34, 23 May 2021EweitzModified title
111024view14:42, 30 June 2020L DupuisConverted interactions in legend to graphical lines
73847view00:33, 26 February 2014MaintBotupdated schema
71764view20:29, 17 October 2013MaintBotremoved data source from nodes without identifier
67695view11:50, 26 June 2013DdiglesOntology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
41259view00:20, 2 March 2011MaintBotRemoved redundant pathway information and comments
34374view22:44, 9 December 2009MaintBotAutomatic update of empty xrefs
28139view21:51, 27 January 2009KhanspersReverted to version '11:31, 14 November 2008' by Khanspers
28138view21:50, 27 January 2009KhanspersChanged name
21221view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:WP258]]: Moved to stable identifier
8436view13:46, 7 January 2008MaintBot[[Pathway:Mouse:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]]: Renaming species
7834view16:21, 18 December 2007MaintBotfixed category names
7305view12:42, 4 November 2007MaintBotAdded categories to GPML
6501view22:19, 22 May 2007A.PandeyReverted to version '14:05, 9 March 2007' by Thomas

External references

DataNodes

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Annotated Interactions

No annotated interactions
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