Non-canonical Wnt pathway (Danio rerio)

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1BMPfgflaminopodaCa2+PDGFFGForganizercytoskeletonother responsive genesventral genesactin polymerizationXnodalpcp pathwayCa-pathwaywnt hompagge_ZF?vangl2 / stbm#axin1Has2groucho2wnt11PKCcamk1gERK2 / MAPK1fzd9wnt7hoxb1bc-mycwnt2bSp5rac2axin2prickle1TMSB4*fzd10dvl2Sp5lrac1camk2dmitfagroucho3ntlfzd7aermshp2 / ptpn11srcsfzd5Nap1*rock1*gsk3bgelsolin-l1#GBPCsk*tbx6bozfzd4lefwnt11rsmoprickle2E12 / tcf3tbx16 / sptstat3ERK1 / MAPK3gelsolin-l2tcf3b / tcf7l1bicatcatenin-beta 2wnt5b#groucho1flamingo 1a / celsr1acofilin 2lYes1evlb#rac3RhoAdNLKlim1otx2jnk1 / mapk8fzd1tcf4cskfzd2spry2cdc42leve1pak1cofilin 2spry4rock2a / rok2fzd8cdvl3wnt3lfzd7bbmp2bwnt10aLRP5PKC#Tak1sqtAPCwnt8bwif1voxFYNprofilin 2#tcf3 / tcf7l1acdc42tclwnt16peadact2 / drapperbmp4wnt7an-waspjnk3 / mapk10#dia1wnt4bwnt10botx1cyclin D1fz12chdknypekgscventlimk1*ephin B1fgf8Arp2dharma/bozcap1wnt8amkp3evlaprofilin2lcdx4dvl2rfzd8bgelsolinRhoAeprickle1rac1wnt2wnt5a*fzd3jnk2 / mapk9*fgf3RhoAa#Arp3c-junflamingo 1b / celsr1b#RhoAccofilin 1vedoepvangl1/stb2daam1#limk2quo#catenin-beta 1RhoAbflhwnt1wnt4aAbi1frzbdvl3sfzd1cdc42l2fzd8agata2CKI-alpha*rock2b


Description

No description

Comments

GenMAPP notes 
* = gene not present in GenMAPP gene database
GenMAPP remarks 
# = gene not represented in Agilent zebrafish 22K oligo set

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Quality Tags

Ontology Terms

 

Bibliography

  1. Krens SF, Corredor-Adamez M, He S, Snaar-Jagalska BE, Spaink HP; ''ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis.''; BMC Genomics, 2008 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
127751view11:25, 2 December 2023EgonwChEBI id for Ca2+ instead of the "Ca" atom
116895view11:22, 15 May 2021EweitzModified title
95547view14:26, 22 December 2017DeSlCOnnected unconnected lines.
95510view00:48, 19 December 2017Khanspersfixed two more xrefs
95509view00:44, 19 December 2017Khanspersremoved GenMAPP comments
95508view00:43, 19 December 2017Khanspersfixed unconnected xrefs and lines
84702view21:39, 15 March 2016KhanspersQuick edit to datanode annotation or property
74203view07:25, 5 April 2014EgonwRemoved a data source where no ID was given.
71974view00:24, 24 October 2013MaintBotUpdated data sources
70259view21:44, 15 July 2013MaintBotupdated to 2013 schema
70194view02:00, 13 July 2013AlexanderPicoModified title
67517view11:20, 26 June 2013DdiglesOntology Term : 'non-canonical Wnt signaling pathway' added !
62784view16:30, 2 May 2013MaintBotupdated uniprot data source
40786view22:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
21131view11:30, 14 November 2008MaintBot[[Pathway:Danio rerio:Wnt Signaling noncanonical]] moved to [[Pathway:WP215]]: Moved to stable identifier
16302view20:47, 17 June 2008Khanspers[[Pathway:Danio rerio:Dr Wnt-signaling noncanonical]] moved to [[Pathway:Danio rerio:Wnt Signaling noncanonical]]: Removed species code prefix from pathway name
14280view07:48, 22 May 2008SFGKrensModified categories
14041view08:12, 21 May 2008SFGKrensNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
APCGeneProduct386762 (Entrez Gene)
Abi1GeneProductDr.107659 (UniGene)
Arp2GeneProductDr.76576 (UniGene)
Arp3GeneProductDr.31830 (UniGene)
CKI-alpha*GeneProduct
Csk*GeneProduct
E12 / tcf3GeneProduct30310 (Entrez Gene)
ERK1 / MAPK3GeneProduct399480 (Entrez Gene)
ERK2 / MAPK1GeneProduct360144 (Entrez Gene)
FYNGeneProductDr.81613 (UniGene)
GBPGeneProduct30719 (Entrez Gene)
Has2GeneProductDr.82516 (UniGene)
LRP5GeneProduct554087 (Entrez Gene)
NLKGeneProduct405892 (Entrez Gene) Nem like kinase
Nap1*GeneProductDr.129724 (UniGene)
PKC#GeneProduct334077 (Entrez Gene)
PKCGeneProduct334077 (Entrez Gene)
RhoAa#GeneProduct406411 (Entrez Gene)
RhoAbGeneProduct336001 (Entrez Gene)
RhoAcGeneProductDr.5516 (UniGene)
RhoAdGeneProduct436718 (Entrez Gene)
RhoAeGeneProductDr.75611 (UniGene)
Sp5GeneProductDr.78633 (UniGene)
Sp5lGeneProduct324261 (Entrez Gene)
TMSB4*GeneProductZDB-GENE-070126- (ZFIN)
Tak1GeneProduct553788 (Entrez Gene)
Yes1GeneProduct407620 (Entrez Gene)
axin1GeneProduct57931 (Entrez Gene) masterblind
axin2GeneProduct58080 (Entrez Gene)
bmp2bGeneProduct30632 (Entrez Gene)
bmp4GeneProduct30612 (Entrez Gene)
bozGeneProduct30170 (Entrez Gene)
c-junGeneProduct335916 (Entrez Gene)
c-mycGeneProduct30686 (Entrez Gene)
camk1gGeneProduct335654 (Entrez Gene)
camk2dGeneProduct436815 (Entrez Gene)
cap1GeneProductDr.6923 (UniGene)
catenin-beta 1GeneProduct30265 (Entrez Gene) ’catenin (cadherin-associated protein), beta 1 ’
catenin-beta 2GeneProduct324004 (Entrez Gene) ’catenin (cadherin-associated protein), beta 2’
cdc42GeneProduct336839 (Entrez Gene)
cdc42l2GeneProduct556226 (Entrez Gene)
cdc42lGeneProductDr.1474 (UniGene)
cdx4GeneProduct30330 (Entrez Gene)
chdGeneProduct30161 (Entrez Gene)
cofilin 1GeneProductDr.76190 (UniGene)
cofilin 2GeneProductDr.79091 (UniGene)
cofilin 2lGeneProductDr.33445 (UniGene)
cskGeneProductDr.41289 (UniGene)
cyclin D1GeneProduct30222 (Entrez Gene)
daam1#GeneProduct378457 (Entrez Gene)
dact2 / drapperGeneProduct337795 (Entrez Gene) ’dapper homolog 2, antagonist of beta-catenin’
dharma/bozGeneProduct30170 (Entrez Gene)
dia1GeneProduct336553 (Entrez Gene)
dvl2GeneProduct323630 (Entrez Gene)
dvl3GeneProduct80972 (Entrez Gene)
ephin B1GeneProduct114377 (Entrez Gene)
ermGeneProduct30452 (Entrez Gene)
eve1GeneProduct30335 (Entrez Gene)
evlaGeneProductDr.17314 (UniGene)
evlb#GeneProduct402929 (Entrez Gene)
fgf3GeneProduct30549 (Entrez Gene)
fgf8GeneProduct30538 (Entrez Gene)
flamingo 1a / celsr1aGeneProductDr.41241 (UniGene)
flamingo 1b / celsr1b#GeneProduct556520 (Entrez Gene)
flhGeneProduct30260 (Entrez Gene)
frzbGeneProduct30119 (Entrez Gene)
fz12GeneProduct30275 (Entrez Gene)
fzd10GeneProduct30366 (Entrez Gene)
fzd1GeneProduct30365 (Entrez Gene)
fzd2GeneProduct30370 (Entrez Gene)
fzd3GeneProduct30371 (Entrez Gene)
fzd4GeneProduct30363 (Entrez Gene)
fzd7aGeneProductDr.4823 (UniGene)
fzd7bGeneProduct30412 (Entrez Gene)
fzd8aGeneProduct58073 (Entrez Gene)
fzd8cGeneProduct30364 (Entrez Gene)
fzd9GeneProduct58023 (Entrez Gene)
gata2GeneProduct30480 (Entrez Gene)
gelsolin-l1#GeneProductDr.31548 (UniGene)
gelsolin-l2GeneProductDr.76196 (UniGene)
gelsolinGeneProduct321099 (Entrez Gene)
groucho1GeneProduct30205 (Entrez Gene)
groucho2GeneProduct30206 (Entrez Gene)
groucho3GeneProduct83411 (Entrez Gene)
gscGeneProduct30212 (Entrez Gene)
gsk3bGeneProduct30654 (Entrez Gene)
hoxb1bGeneProduct30374 (Entrez Gene)
icatGeneProduct58117 (Entrez Gene) beta-catenin-interacting protein
jnk1 / mapk8GeneProductDr.82505 (UniGene)
jnk2 / mapk9*GeneProduct
jnk3 / mapk10#GeneProductDr.49078 (UniGene)
knypekGeneProduct118437 (Entrez Gene)
lefGeneProduct30701 (Entrez Gene)
lim1GeneProduct30463 (Entrez Gene)
limk1*GeneProduct735292 (Entrez Gene)
limk2GeneProductDr.76343 (UniGene)
mitfaGeneProduct30080 (Entrez Gene)
mkp3GeneProduct353314 (Entrez Gene)
n-waspGeneProductDr.83257 (UniGene)
ntlGeneProduct30399 (Entrez Gene)
oepGeneProduct30304 (Entrez Gene)
otx1GeneProduct30500 (Entrez Gene)
otx2GeneProduct30501 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
peaGeneProduct30700 (Entrez Gene)
prickle1GeneProduct368249 (Entrez Gene)
prickle1GeneProductDr.51819 (UniGene)
prickle2GeneProduct368250 (Entrez Gene)
profilin 2#GeneProductDr.1150 (UniGene)
profilin2lGeneProductDr.75574 (UniGene)
quo#GeneProduct321031 (Entrez Gene)
rac1GeneProductDr.4711 (UniGene)
rac2GeneProduct415151 (Entrez Gene)
rac3GeneProduct437027 (Entrez Gene)
rfzd8bGeneProduct58072 (Entrez Gene)
rock1*GeneProduct
rock2a / rok2GeneProductDr.1706 (UniGene)
rock2bGeneProductQ5SP91 (Uniprot-TrEMBL)
sfzd1GeneProduct402843 (Entrez Gene) secreted frizzled-related protein
sfzd5GeneProduct117510 (Entrez Gene) secreted frizzled-related protein
shp2 / ptpn11GeneProductDr.104919 (UniGene)
smoGeneProduct30225 (Entrez Gene)
spry2GeneProduct335098 (Entrez Gene)
spry4GeneProduct114437 (Entrez Gene)
sqtGeneProduct30153 (Entrez Gene)
srcGeneProductDr.2731 (UniGene)
stat3GeneProduct30767 (Entrez Gene)
tbx16 / sptGeneProduct30264 (Entrez Gene)
tbx6GeneProduct30254 (Entrez Gene)
tcf3 / tcf7l1aGeneProduct30523 (Entrez Gene)
tcf3b / tcf7l1bGeneProduct30556 (Entrez Gene)
tcf4GeneProduct30510 (Entrez Gene)
tclGeneProduct386615 (Entrez Gene) secreted frizzled-related protein
vangl1/stb2GeneProductDr.84827 (UniGene)
vangl2 / stbm#GeneProduct245949 (Entrez Gene)
vedGeneProduct368201 (Entrez Gene)
ventGeneProduct64810 (Entrez Gene)
voxGeneProduct64807 (Entrez Gene)
wif1GeneProduct30476 (Entrez Gene) wnt inhibitory factor 1
wnt10aGeneProduct30171 (Entrez Gene)
wnt10bGeneProduct30308 (Entrez Gene)
wnt11GeneProduct30139 (Entrez Gene) silberblick
wnt11rGeneProductDr.76466 (UniGene)
wnt1GeneProduct30128 (Entrez Gene)
wnt16GeneProduct404628 (Entrez Gene)
wnt2GeneProduct30127 (Entrez Gene)
wnt2bGeneProduct359837 (Entrez Gene)
wnt3lGeneProduct60632 (Entrez Gene)
wnt4aGeneProduct30123 (Entrez Gene)
wnt4bGeneProduct57928 (Entrez Gene)
wnt5a*GeneProductZDB-GENE-060328-3 (ZFIN)
wnt5b#GeneProduct30105 (Entrez Gene)
wnt7GeneProduct60633 (Entrez Gene)
wnt7aGeneProduct565714 (Entrez Gene)
wnt8aGeneProduct30122 (Entrez Gene)
wnt8bGeneProduct30144 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP215"
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