Proteasome degradation (Drosophila melanogaster)

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AMP Ubiquitin/E1 ComplexAlpha subunitsUbiquitin/E2 Complex20S ComplexATPLid subunitsCatalytic Core (p45)Proteasome 20SCytosolic ProteinsE3/ProteinDegrades only PeptidesUnfolds and DegradesBeta subunits(PA700) (ATP dependent)Oxidatively DamagedPresentation by MHC class 1Proteins to be DegradedActivators ofProteasome 26 SIntact Proteinsp45 ATPase SubunitUbiquitin/Proteinpsmc4zgc:92643HLA-GPSMA1PSMB10zgc:110330ube1rpn2psmc6HLA-AUBCPSMB3zgc:92282psmd2HIST1H2ABpsmd10UBE1Lzgc:110710psmb7PSMB9zgc:110247psmb6PSMA6HLA-Jzgc:77139UBE2D3UBE2BHLA-Fpsme1HLA-BPSMD3H2AFZp44S10h2afxzgc:73096HLA-HPSMD7psmd12zgc:92464PSMD5psmd11psmb8IFNGzgc:86762zgc:92464UBE2D2psme3psmc1psmb1psmc2psmc3NEDD4psma4HLA-Epsmb5psma5PSMA3psmd1psme2psmd13RPN1HLA-C


Description

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Quality Tags

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Bibliography

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History

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CompareRevisionActionTimeUserComment
116929view09:46, 16 May 2021EweitzModified title
79434view02:57, 22 March 2015Khanspersupdate schema
79433view02:56, 22 March 2015KhanspersReverted to version '11:33, 26 June 2013' by Khanspers
77443view20:28, 8 September 2014MaintBotremoved old homology label
71516view19:22, 17 October 2013MaintBotAutomated update of data sources
68725view21:59, 6 July 2013MaintBotUpdated to 2013 gpml schema
67612view11:33, 26 June 2013DdiglesOntology Term : 'ubiquitin/proteasome degradation pathway' added !
40900view22:35, 1 March 2011MaintBotRemoved redundant pathway information and comments
21271view11:31, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Proteasome Degradation]] moved to [[Pathway:WP281]]: Moved to stable identifier
9026view14:15, 7 January 2008MaintBotAdded to category $category
9024view14:14, 7 January 2008NsalomonisUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
H2AFZGeneProduct
HIST1H2ABGeneProduct
HLA-AGeneProduct
HLA-BGeneProduct
HLA-CGeneProduct
HLA-EGeneProduct
HLA-FGeneProduct
HLA-GGeneProduct
HLA-HGeneProduct
HLA-JGeneProduct
IFNGGeneProduct
NEDD4GeneProduct
PSMA1GeneProduct
PSMA3GeneProduct
PSMA6GeneProduct
PSMB10GeneProduct64280 (Entrez Gene)
PSMB3GeneProduct573095 (Entrez Gene)
PSMB9GeneProduct
PSMD3GeneProduct393544 (Entrez Gene)
PSMD5GeneProduct
PSMD7GeneProduct327330 (Entrez Gene)
RPN1GeneProduct325561 (Entrez Gene)
UBCGeneProduct
UBE1LGeneProduct
UBE2BGeneProduct
UBE2D2GeneProduct335444 (Entrez Gene)
UBE2D3GeneProduct
h2afxGeneProduct394048 (Entrez Gene)
p44S10GeneProduct
psma4GeneProduct326687 (Entrez Gene)
psma5GeneProduct403011 (Entrez Gene)
psmb1GeneProduct445413 (Entrez Gene)
psmb5GeneProduct30387 (Entrez Gene)
psmb6GeneProduct30388 (Entrez Gene) U13393
psmb7GeneProduct64278 (Entrez Gene)
psmb8GeneProduct30666 (Entrez Gene)
psmc1GeneProduct336786 (Entrez Gene)
psmc2GeneProduct393941 (Entrez Gene)
psmc3GeneProduct321947 (Entrez Gene)
psmc4GeneProduct326884 (Entrez Gene) PRS6_HUMAN
psmc6GeneProduct321585 (Entrez Gene)
psmd10GeneProduct403085 (Entrez Gene)
psmd11GeneProduct322265 (Entrez Gene)
psmd12GeneProduct321898 (Entrez Gene)
psmd13GeneProduct393922 (Entrez Gene)
psmd1GeneProduct394159 (Entrez Gene)
psmd2GeneProduct393518 (Entrez Gene)
psme1GeneProduct30648 (Entrez Gene)
psme2GeneProduct30647 (Entrez Gene)
psme3GeneProduct30649 (Entrez Gene)
rpn2GeneProduct335985 (Entrez Gene)
ube1GeneProduct406335 (Entrez Gene)
zgc:110247GeneProduct550287 (Entrez Gene)
zgc:110330GeneProduct550499 (Entrez Gene)
zgc:110710GeneProduct554153 (Entrez Gene)
zgc:73096GeneProduct324015 (Entrez Gene)
zgc:77139GeneProduct406445 (Entrez Gene)
zgc:86762GeneProduct415221 (Entrez Gene)
zgc:92282GeneProduct436882 (Entrez Gene)
zgc:92464GeneProduct445285 (Entrez Gene) PRS6_HUMAN
zgc:92643GeneProduct436709 (Entrez Gene)

Annotated Interactions

No annotated interactions

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