Nuclear receptors meta-pathway (Homo sapiens)

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14, 18CAR target genesCAR/PXR Ligand29IP6K3SULT2A1SLC26A2TGFB2UGT1A9EDN2SLC19A2CBR3CYP2B6ANKRD1SLC2A14CYP7A1CYP3A5NFE2L2CYP2A6DegradationGSTA1POU5F1SLC2A12CES2SLC2A4DNAJC15GSTA2ABCC3FKBP5UGT1A1EHHADHAMIGO2DNERBile acid &xenobiotics transportPDK4SERPINA1CYP2C19PPARDIL1BPPP1R14CBIRC2CYP7A1CBR1GPR115PCK1KAT2BIL17BSLC2A10GSTP1bile acidconjugationPPARGC1AIRS2UGT1A7DNAJB1DNAJC7IL11ENC1TSC22D3MetabolismSERPINB2CES4AMAFFCDC42EP3SLC7A11GCC1AKAP13UGT1A9JUNGSTT1G6PDNR1I3HSP90AB1KTN1FGFBP1PRDX6IL12AGADD45BFGD4UGT1A9CYP7A1CYP8B1NAV3CXCR7CYP2B6KEAP1HGFUGT1A3ALAS1GPX3SRCPRRG4STAT3ABCB11RXRACES1ABCC4ANGPTL4ME1CYP3A4GCLCSLC2A6IL12BTXNRD3BLVRBDrug and steroidmetabolismLRRC8ASLC2A7UGT1A4AntioxidantproteinsSULT1A1GGT1POLKCPEB4ABCB4FGF19SP1UGT2B7JUNBCYP3A7SP1STOMTGFAHSP90AA1PPP2R4NCOA6GSTA5SPINK13SRGNTNFAIP3ABCG5NR1H4CES3CCL20MGST1CYP1A2BAATADH7GPAMFASNARL5BTGFB1NFKB2SLC2A3HMOX1SREBF1SULT2A1HBEGFCo-activatorsABCC5CYP1A1ABCC2SLC27A5ALDH3A1SDPRETNK2InflammationCell proliferationand differentiationSLC2A2UGT1A6ABCB1SRXN1JUNCYP4A11SLC2A11SLC2A5MAFGCAP2SLC2A13CYP4A11SMARCA1GSTA4NCOA1SCNN1AB3GNT5PRDX1FTH1BHLHE40GSTA2CYP3A4IFNGCUL1PPARAABCC2TranscriptionfactorsFTLUGT1A1SLC7A5UGT1A3SERPINB9ALOX5APSERTAD2SMC1AEPHA2SNAI2SLCO2B1Bile acidneosynthesisHSP90AA1THBDGCLMCCL2CYP2A6PGDMGST3NR3C1UGT1A4CES5AUGT1A3SLC2A9ZIC2GPR153S100PNQO1CES3SEC14L1NR1H3NR0B2TXNRD1NCOA2SPRY1MFGE8GPX2SLC10A1CDKN1CABHD2PTGS2CYP1B1TGFBR3PPARGC1APTGR1PLK2OtherACOX1FGF13PDGFBACAA1Phase 2metabolismEGR1TranscriptionfactorsNRG1HSPA1ASLC2A8TXNABCC3TGFB1MYOFSLC2A1TNS4ABCG8CYP2C9CYP3A4NR0B2MGST2BIRC3AGERSOD3EPHA3UGT1A4SULT2A1TGFBR2PMP2PDE4BEP300MT1IPPPARARGS2GSTT2UGT1A7MGAMCell proliferationand apoptosisNR0B2ESR1UGT1A6CYP2A6GSTA3EPB41L4BSQSTM1GSRUGT2B4484444339423732010373377302222394442213939393720NR1I3153912741393912, 36399392839443374337382627373713274813928282341639524834339483974334LigandDNAJC7HSP90AA1CoregulatorsGenesTATA boxPBREMRXRANR1I3LigandCo-activatorsNCOA1EGFR pathwayEP300UGT1A64, 24, 39AHRR3SRCCDKN1BAIP3CYP1B11, 3, 4, 24, 41UGT1A14, 24, 39ALDH3A11GSTA2AHR4, 24JUNDNQO1494, 24IGFBP132NFE2L224BAXJUN321CYP1A21, 3, 4, 24, 41EGFRHSP90AA1TNFPTGES3IL211HES12ARNTCDC37CYP1A11, 3, 4, 24, 41AHRARNTAIPSRCSRCCDC37AHRARNTAHRLigandLigandLigandXREGenesTATA boxUGT1A938, 39HepatocyteproliferationNR1H338SCP238CPT1AAPOC33838FABP1CCND138PLTP3838DBI38APOA2CPT23838APOA1CYP4A113838ACADM38CDK438CYP7A1MYC38mitochondrialomega-oxidation38SLC27A138Cholesterolcatabolismperoxisomalbeta-oxidationKLK1538APOA538CDK138CYP8B138PPAR alpha ligandPPARAGenesTATA boxPPREPPARARXRALigandlipoproteinmetabolismfatty acidtransportmitochondrialbeta-oxidationPXR target genes43, 50SLCO1B1HSP90AA150NR1I2SRPX2NCOA3FOXO1CYP4F1245CYP3A4504UGT1A150DNAJC7ABCC450NRIP1UnknownCYP2B64GSTA2PSMC550PPARGC1ANCOA1NCOA2ABCB150NR1I2LigandCoregulatorsGenesTATA boxXRERXRANR1I2LigandAhR LigandCo-activatorsGenesTATA boxNR1I346NR1I246NR3C1RXRA12, 36, 46NR1I3NR1I2NR3C1HSP90AA1GR ligandp23HSP90AA1p23NR3C1HSP90AA15, 30p23NR3C130LigandNR3C1Ligand30LigandLigandNR3C1NR3C1LigandLigandGREGenesTATA boxNR3C1NR3C1LigandLigandnGRECoregulatorsGR inhibitorytarget genesLXR ligandNR1H3LigandRXRA12, 36PTGES3RXRA12, 36NR1H3CYP2B637CYP2C937GenesTATA boxVDREVDR target genesVDR30, 40LigandRXRACYP3A437VDRVDR ligandRXRAVDRLigandER ligandESR1ESR1LigandLigandGenesTATA boxEREESR1LigandESR1LigandESR110ESR1ESR1LigandLigandCoregulatorsER target genes8GenesTATA boxNR1H3LigandLXRERXRALXR target genes12, 36FXR ligandNR1H4RXRA26LigandGenesTATA boxNR1H426RXRALigandFXREBile aciddetoxification28NR1H426LigandUGT1A4UGT1A639UGT1A939UGT1A33939CYP2C94CYP3A5CYP2C194SULT2A1444ABCC2ABCC33737EHHADH48FOXO1Inflammation4516Growth andapoptosis16SignaltransductionOther1616InflammationGrowth andapoptosis16Signaltransduction16Metabolism1616Transport16Other16NuclearreceptorsFXR Target genesOtherGR stimulatorytarget genesMulti-drugresistanceDrug and steroidmetabolismPhase 2metabolismMulti-drugresistanceOtherOtherPhase 2metabolismDrug and steroidmetabolismPhase 2metabolismOtherDrug and steroidmetabolismMulti-drugresistanceTranscriptionfactorsOtherDrug and steroidmetabolismTranscriptionfactorsOtherDrug and steroidmetabolismPPAR alphatarget genesAhR target genesGenesTATA boxRXRALigandARENRF2 targetgenesOtherPhase 1proteins7Phase 2proteins7GSTM57GSTM1GSTM2GSTM3GSTM4TransportSLC5A27SLC5A1SLC5A4SLC5A10SLC5A9SLC5A6SLC5A11SLC5A12SLC5A3SLC5A7SLC5A8SLC5A5SLC6A2SLC6A1SLC6A4SLC6A11SLC6A9SLC6A6SLC6A13SLC6A14SLC6A3SLC6A7SLC6A8SLC6A5SLC6A16SLC6A15SLC6A18SLC6A20SLC6A17SLC6A19SLC39A2SLC39A1SLC39A4SLC39A10SLC39A9SLC39A6SLC39A11SLC39A12SLC39A3SLC39A7SLC39A8SLC39A5SLC39A13SLC39A14Growth factorsand receptors7NFE2L2NRF2 ligandKEAP1NFE2L2LigandNFE2L2NFE2L2SCD


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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
126680view16:51, 11 June 2023EgonwFixed character encoding issues
126012view11:37, 26 March 2023EgonwWrong ligand term
125859view10:46, 13 March 2023DeSlFixed last 'ligand' classified as protein
125858view10:44, 13 March 2023DeSlResolved typo in description
125857view10:43, 13 March 2023DeSlRemoved empty comment from Description
125856view10:42, 13 March 2023DeSlConnected unconnected line
125855view10:41, 13 March 2023DeSlConverted textLabels 'ligand; to DataNode Metabolite, with ChEBI annotation; changed two protein datanodes to metaboliute for ligand.
125833view07:00, 13 March 2023EgonwAdded ChEBI identifiers for ligands
120815view15:30, 11 January 2022SusanOntology Term : 'transcription factor mediated signaling pathway' added !
117808view14:40, 22 May 2021EweitzModified title
115341view14:20, 14 February 2021EgonwMade more pathways clickable
103038view11:54, 2 February 2019MaintBotReplaced an outdated Ensembl identifiers with the new one.
97489view13:23, 23 May 2018Fehrhartlayout
97488view13:17, 23 May 2018Fehrhartadded annotations
97487view13:08, 23 May 2018Fehrhartadded annotations
97484view12:58, 23 May 2018FehrhartModified description
97483view12:56, 23 May 2018Fehrhartadded annotations
97481view12:50, 23 May 2018Fehrhartadded annotations
97480view12:42, 23 May 2018Fehrhartadded annotations
97479view12:35, 23 May 2018Fehrhartadded annotations
97478view12:12, 23 May 2018FehrhartModified description
97477view12:11, 23 May 2018FehrhartModified description
97476view12:07, 23 May 2018Fehrhartall connections done (hopefully)
97475view12:04, 23 May 2018Fehrhartconnections
97474view12:02, 23 May 2018Fehrhartconnections...
97473view12:00, 23 May 2018Fehrhartfixed connections
97472view11:58, 23 May 2018Fehrhartfixed connections
97471view11:56, 23 May 2018Fehrhartfixed connections
97470view11:55, 23 May 2018Fehrhartfixed more connections
97469view11:53, 23 May 2018Fehrhartfixed more connections
97467view09:20, 23 May 2018Fehrhartfixed more connections
97463view08:48, 22 May 2018Fehrhartfixed connections
87959view13:12, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
83040view04:29, 18 November 2015Mkutmonfixed issue with references
83016view13:30, 17 November 2015FehrhartUpdate of outdated identifiers
79825view08:28, 17 April 2015EgonwFixed the Ensembl data source.
78569view14:50, 7 January 2015MaintBotadded missing graphIds
78210view14:44, 14 December 2014EgonwChanged schema.
78209view14:42, 14 December 2014MaintBotModified title
78095view11:38, 2 December 2014RiannefijtenNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABCB11GeneProductENSG00000073734 (Ensembl Human)
ABCB1GeneProductENSG00000085563 (Ensembl Human)
ABCB4GeneProductENSG00000005471 (Ensembl Human)
ABCC2GeneProductENSG00000023839 (Ensembl Human)
ABCC3GeneProductENSG00000108846 (Ensembl Human)
ABCC4GeneProductENSG00000125257 (Ensembl Human)
ABCC5GeneProductENSG00000114770 (Ensembl Human)
ABCG5GeneProductENSG00000138075 (Ensembl Human)
ABCG8GeneProductENSG00000143921 (Ensembl Human)
ABHD2GeneProductENSG00000140526 (Ensembl Human)
ACAA1GeneProductENSG00000060971 (Ensembl Human)
ACADMGeneProductENSG00000117054 (Ensembl Human)
ACOX1GeneProductENSG00000161533 (Ensembl Human)
ADH7GeneProductENSG00000196344 (Ensembl Human)
AGERGeneProductENSG00000204305 (Ensembl Human)
AHRGeneProductENSG00000106546 (Ensembl Human)
AHRRGeneProductENSG00000063438 (Ensembl Human)
AIPGeneProductENSG00000110711 (Ensembl Human)
AKAP13GeneProductENSG00000170776 (Ensembl Human)
ALAS1GeneProductENSG00000023330 (Ensembl Human)
ALDH3A1GeneProductENSG00000108602 (Ensembl Human)
ALOX5APGeneProductENSG00000132965 (Ensembl Human)
AMIGO2GeneProductENSG00000139211 (Ensembl Human)
ANGPTL4GeneProductENSG00000167772 (Ensembl Human)
ANKRD1GeneProductENSG00000148677 (Ensembl Human)
APOA1GeneProductENSG00000118137 (Ensembl Human)
APOA2GeneProductENSG00000158874 (Ensembl Human)
APOA5GeneProductENSG00000110243 (Ensembl Human)
APOC3GeneProductENSG00000110245 (Ensembl Human)
ARL5BGeneProductENSG00000165997 (Ensembl Human)
ARNTGeneProduct405 (Entrez Gene)
Antioxidant proteinsPathway
B3GNT5GeneProductENSG00000176597 (Ensembl Human)
BAATGeneProductENSG00000136881 (Ensembl Human)
BAX GeneProductENSG00000087088 (Ensembl Human)
BHLHE40GeneProductENSG00000134107 (Ensembl Human)
BIRC2GeneProductENSG00000110330 (Ensembl Human)
BIRC3GeneProductENSG00000023445 (Ensembl Human)
BLVRBGeneProductENSG00000090013 (Ensembl Human)
Bile acid detoxificationPathway
Bile acid neosynthesisPathway
Bile acid & xenobiotics transportPathway
CAP2GeneProductENSG00000112186 (Ensembl Human)
CBR1GeneProductENSG00000159228 (Ensembl Human)
CBR3GeneProductENSG00000159231 (Ensembl Human)
CCL20GeneProductENSG00000115009 (Ensembl Human)
CCL2GeneProductENSG00000108691 (Ensembl Human)
CCND1GeneProductENSG00000110092 (Ensembl Human)
CDC37GeneProductENSG00000105401 (Ensembl Human)
CDC42EP3GeneProductENSG00000163171 (Ensembl Human)
CDK1GeneProductENSG00000170312 (Ensembl Human)
CDK4GeneProductENSG00000135446 (Ensembl Human)
CDKN1BGeneProductENSG00000111276 (Ensembl Human)
CDKN1CGeneProductENSG00000129757 (Ensembl Human)
CES1GeneProductENSG00000198848 (Ensembl Human)
CES2GeneProductENSG00000172831 (Ensembl Human)
CES3GeneProductENSG00000172828 (Ensembl Human)
CES4AGeneProductENSG00000172824 (Ensembl Human)
CES5AGeneProductENSG00000159398 (Ensembl Human)
CPEB4GeneProductENSG00000113742 (Ensembl Human)
CPT1AGeneProductENSG00000110090 (Ensembl Human)
CPT2GeneProductENSG00000157184 (Ensembl Human)
CUL1GeneProductENSG00000055130 (Ensembl Human)
CXCR7GeneProductENSG00000144476 (Ensembl Human)
CYP1A1GeneProductENSG00000140465 (Ensembl Human)
CYP1A2GeneProductENSG00000140505 (Ensembl Human)
CYP1B1GeneProductENSG00000138061 (Ensembl Human)
CYP2A6GeneProductENSG00000255974 (Ensembl Human)
CYP2B6GeneProductENSG00000197408 (Ensembl Human)
CYP2C19GeneProductENSG00000165841 (Ensembl Human)
CYP2C9GeneProductENSG00000138109 (Ensembl Human)
CYP3A4GeneProductENSG00000160868 (Ensembl Human)
CYP3A5GeneProductENSG00000106258 (Ensembl Human)
CYP3A7GeneProductENSG00000160870 (Ensembl Human)
CYP4A11GeneProductENSG00000187048 (Ensembl Human)
CYP4F12GeneProductENSG00000186204 (Ensembl Human)
CYP7A1GeneProductENSG00000167910 (Ensembl Human)
CYP8B1GeneProductENSG00000180432 (Ensembl Human)
Cell proliferation and apoptosisPathway
Cell proliferation

and differentiation

Pathway
Cholesterol catabolismPathway
Co-activators
DBIGeneProductENSG00000155368 (Ensembl Human)
DNAJB1GeneProductENSG00000132002 (Ensembl Human)
DNAJC15GeneProductENSG00000120675 (Ensembl Human)
DNAJC7GeneProductENSG00000168259 (Ensembl Human)
DNERGeneProductENSG00000187957 (Ensembl Human)
DegradationPathway
Drug and steroid metabolismPathway
EDN2GeneProductENSG00000127129 (Ensembl Human)
EGFR pathwayPathway
EGFRGeneProductENSG00000146648 (Ensembl Human)
EGR1GeneProductENSG00000120738 (Ensembl Human)
EHHADHGeneProductENSG00000113790 (Ensembl Human)
ENC1GeneProductENSG00000171617 (Ensembl Human)
EP300GeneProductENSG00000100393 (Ensembl Human)
EPB41L4BGeneProductENSG00000095203 (Ensembl Human)
EPHA2GeneProductENSG00000142627 (Ensembl Human)
EPHA3GeneProductENSG00000044524 (Ensembl Human)
ESR1GeneProductENSG00000091831 (Ensembl Human)
ETNK2GeneProductENSG00000143845 (Ensembl Human)
FABP1GeneProductENSG00000163586 (Ensembl Human)
FASNGeneProductENSG00000169710 (Ensembl Human)
FGD4GeneProductENSG00000139132 (Ensembl Human)
FGF13GeneProductENSG00000129682 (Ensembl Human)
FGF19GeneProductENSG00000162344 (Ensembl Human)
FGFBP1GeneProductENSG00000137440 (Ensembl Human)
FKBP5GeneProductENSG00000096060 (Ensembl Human)
FOXO1GeneProductENSG00000150907 (Ensembl Human)
FTH1GeneProductENSG00000167996 (Ensembl Human)
FTLGeneProductENSG00000087086 (Ensembl Human)
G6PDGeneProductENSG00000160211 (Ensembl Human)
GADD45BGeneProductENSG00000099860 (Ensembl Human)
GCC1GeneProductENSG00000179562 (Ensembl Human)
GCLCGeneProductENSG00000001084 (Ensembl Human)
GCLMGeneProductENSG00000023909 (Ensembl Human)
GGT1GeneProductENSG00000100031 (Ensembl Human)
GPAMGeneProductENSG00000119927 (Ensembl Human)
GPR115GeneProductENSG00000153294 (Ensembl Human)
GPR153GeneProductENSG00000158292 (Ensembl Human)
GPX2GeneProductENSG00000176153 (Ensembl Human)
GPX3GeneProductENSG00000211445 (Ensembl Human)
GSRGeneProductENSG00000104687 (Ensembl Human)
GSTA1GeneProductENSG00000243955 (Ensembl Human)
GSTA2GeneProductENSG00000244067 (Ensembl Human)
GSTA3GeneProductENSG00000174156 (Ensembl Human)
GSTA4GeneProductENSG00000170899 (Ensembl Human)
GSTA5GeneProductENSG00000182793 (Ensembl Human)
GSTM1GeneProductENSG00000134184 (Ensembl Human)
GSTM2GeneProductENSG00000213366 (Ensembl Human)
GSTM3GeneProductENSG00000134202 (Ensembl Human)
GSTM4GeneProductENSG00000168765 (Ensembl Human)
GSTM5GeneProductENSG00000134201 (Ensembl Human)
GSTP1GeneProductENSG00000084207 (Ensembl Human)
GSTT1GeneProductENSG00000184674 (Ensembl Human)
GSTT2GeneProductENSG00000099984 (Ensembl Human)
Growth and apoptosisPathway
Growth factors and receptorsPathway
HBEGFGeneProductENSG00000113070 (Ensembl Human)
HES1GeneProductENSG00000114315 (Ensembl Human)
HGFGeneProductENSG00000019991 (Ensembl Human)
HMOX1GeneProductENSG00000100292 (Ensembl Human)
HSP90AA1 GeneProductENSG00000080824 (Ensembl Human)
HSP90AA1GeneProductENSG00000080824 (Ensembl Human)
HSP90AB1GeneProductENSG00000096384 (Ensembl Human)
HSPA1AGeneProductENSG00000204389 (Ensembl Human)
Hepatocyte proliferationPathwayin mice (possibly also in humans?)
IFNGGeneProductENSG00000111537 (Ensembl Human)
IGFBP1 GeneProductENSG00000146678 (Ensembl Human)
IL11GeneProductENSG00000095752 (Ensembl Human)
IL12AGeneProductENSG00000168811 (Ensembl Human)
IL12BGeneProductENSG00000113302 (Ensembl Human)
IL17BGeneProductENSG00000127743 (Ensembl Human)
IL1BGeneProductENSG00000125538 (Ensembl Human)
IL2 GeneProductENSG00000109471 (Ensembl Human)
IP6K3GeneProductENSG00000161896 (Ensembl Human)
IRS2GeneProductENSG00000185950 (Ensembl Human)
InflammationPathway
JUNBGeneProductENSG00000171223 (Ensembl Human)
JUNDGeneProductENSG00000130522 (Ensembl Human)
JUNGeneProductENSG00000177606 (Ensembl Human)
KAT2BGeneProductENSG00000114166 (Ensembl Human)
KEAP1GeneProductENSG00000079999 (Ensembl Human)
KLK15GeneProductENSG00000174562 (Ensembl Human)
KTN1GeneProductENSG00000126777 (Ensembl Human)
LRRC8AGeneProductENSG00000136802 (Ensembl Human)
Ligand
Ligand ProteinOmeprazole, TCDD, PCB
MAFFGeneProductENSG00000185022 (Ensembl Human)
MAFGGeneProductENSG00000197063 (Ensembl Human)
ME1GeneProductENSG00000065833 (Ensembl Human)
MFGE8GeneProductENSG00000140545 (Ensembl Human)
MGAMGeneProductENSG00000179087 (Ensembl Human)
MGST1GeneProductENSG00000008394 (Ensembl Human)
MGST2GeneProductENSG00000085871 (Ensembl Human)
MGST3GeneProductENSG00000143198 (Ensembl Human)
MT1IPGeneProduct644314 (Entrez Gene)
MYCGeneProductENSG00000136997 (Ensembl Human)
MYOFGeneProductENSG00000138119 (Ensembl Human)
MetabolismPathway
Multi-drug resistancePathway
NAV3GeneProductENSG00000067798 (Ensembl Human)
NCOA1GeneProductENSG00000084676 (Ensembl Human)
NCOA2GeneProductENSG00000140396 (Ensembl Human)
NCOA3GeneProductENSG00000124151 (Ensembl Human)
NCOA6GeneProductENSG00000198646 (Ensembl Human)
NFE2L2GeneProductENSG00000116044 (Ensembl Human)
NFKB2GeneProductENSG00000077150 (Ensembl Human)
NQO1GeneProductENSG00000181019 (Ensembl Human)
NR0B2GeneProductENSG00000131910 (Ensembl Human)
NR1H3GeneProductENSG00000025434 (Ensembl Human)
NR1H4GeneProductENSG00000012504 (Ensembl Human)
NR1I2GeneProductENSG00000144852 (Ensembl Human)
NR1I3GeneProductENSG00000143257 (Ensembl Human)
NR3C1GeneProductENSG00000113580 (Ensembl Human)
NRG1GeneProductENSG00000157168 (Ensembl Human)
NRIP1GeneProductENSG00000180530 (Ensembl Human)
Nuclear receptorsPathway
OtherPathway
PCK1GeneProductENSG00000124253 (Ensembl Human)
PDE4BGeneProductENSG00000184588 (Ensembl Human)
PDGFBGeneProductENSG00000100311 (Ensembl Human)
PDK4GeneProductENSG00000004799 (Ensembl Human)
PGDGeneProductENSG00000142657 (Ensembl Human)
PLK2GeneProductENSG00000145632 (Ensembl Human)
PLTPGeneProductENSG00000100979 (Ensembl Human)
PMP2GeneProductENSG00000147588 (Ensembl Human)
POLKGeneProductENSG00000122008 (Ensembl Human)
POU5F1GeneProductENSG00000204531 (Ensembl Human)
PPAR alpha ligand
PPARAGeneProductENSG00000186951 (Ensembl Human)
PPARDGeneProductENSG00000112033 (Ensembl Human)
PPARGC1AGeneProductENSG00000109819 (Ensembl Human)
PPP1R14CGeneProductENSG00000198729 (Ensembl Human)
PPP2R4GeneProductENSG00000119383 (Ensembl Human) plays a role in translocation of CAR
PRDX1GeneProductENSG00000117450 (Ensembl Human)
PRDX6GeneProductENSG00000117592 (Ensembl Human)
PRRG4GeneProductENSG00000135378 (Ensembl Human)
PSMC5GeneProductENSG00000087191 (Ensembl Human)
PTGES3GeneProductENSG00000110958 (Ensembl Human)
PTGR1GeneProductENSG00000106853 (Ensembl Human)
PTGS2GeneProductENSG00000073756 (Ensembl Human)
Phase 1

proteins

Pathway
Phase 2 metabolismPathway
Phase 2

proteins

Pathway
RGS2GeneProductENSG00000116741 (Ensembl Human)
RXRAGeneProductENSG00000186350 (Ensembl Human)
S100PGeneProductENSG00000163993 (Ensembl Human)
SCDGeneProductENSG00000099194 (Ensembl Human)
SCNN1AGeneProductENSG00000111319 (Ensembl Human)
SCP2GeneProductENSG00000116171 (Ensembl Human)
SDPRGeneProductENSG00000168497 (Ensembl Human)
SEC14L1GeneProductENSG00000129657 (Ensembl Human)
SERPINA1GeneProductENSG00000197249 (Ensembl Human)
SERPINB2GeneProductENSG00000197632 (Ensembl Human)
SERPINB9GeneProductENSG00000170542 (Ensembl Human)
SERTAD2GeneProductENSG00000179833 (Ensembl Human)
SLC10A1GeneProductENSG00000100652 (Ensembl Human) inhibition
SLC19A2GeneProductENSG00000117479 (Ensembl Human)
SLC26A2GeneProductENSG00000155850 (Ensembl Human)
SLC27A1GeneProductENSG00000130304 (Ensembl Human)
SLC27A5GeneProductENSG00000083807 (Ensembl Human)
SLC2A10GeneProductENSG00000197496 (Ensembl Human)
SLC2A11GeneProductENSG00000133460 (Ensembl Human)
SLC2A12GeneProductENSG00000146411 (Ensembl Human)
SLC2A13GeneProductENSG00000151229 (Ensembl Human)
SLC2A14GeneProductENSG00000173262 (Ensembl Human)
SLC2A1GeneProductENSG00000117394 (Ensembl Human)
SLC2A2GeneProductENSG00000163581 (Ensembl Human)
SLC2A3GeneProductENSG00000059804 (Ensembl Human)
SLC2A4GeneProductENSG00000181856 (Ensembl Human)
SLC2A5GeneProductENSG00000142583 (Ensembl Human)
SLC2A6GeneProductENSG00000160326 (Ensembl Human)
SLC2A7GeneProductENSG00000197241 (Ensembl Human)
SLC2A8GeneProductENSG00000136856 (Ensembl Human)
SLC2A9GeneProductENSG00000109667 (Ensembl Human)
SLC39A10GeneProductENSG00000196950 (Ensembl Human)
SLC39A11GeneProductENSG00000133195 (Ensembl Human)
SLC39A12GeneProductENSG00000148482 (Ensembl Human)
SLC39A13GeneProductENSG00000165915 (Ensembl Human)
SLC39A14GeneProductENSG00000104635 (Ensembl Human)
SLC39A1GeneProductENSG00000143570 (Ensembl Human)
SLC39A2GeneProductENSG00000165794 (Ensembl Human)
SLC39A3GeneProductENSG00000141873 (Ensembl Human)
SLC39A4GeneProductENSG00000147804 (Ensembl Human)
SLC39A5GeneProductENSG00000139540 (Ensembl Human)
SLC39A6GeneProductENSG00000141424 (Ensembl Human)
SLC39A7GeneProductENSG00000112473 (Ensembl Human)
SLC39A8GeneProductENSG00000138821 (Ensembl Human)
SLC39A9GeneProductENSG00000029364 (Ensembl Human)
SLC5A10GeneProductENSG00000154025 (Ensembl Human)
SLC5A11GeneProductENSG00000158865 (Ensembl Human)
SLC5A12GeneProductENSG00000148942 (Ensembl Human)
SLC5A1GeneProductENSG00000100170 (Ensembl Human)
SLC5A2GeneProductENSG00000140675 (Ensembl Human)
SLC5A3GeneProductENSG00000198743 (Ensembl Human)
SLC5A4GeneProductENSG00000100191 (Ensembl Human)
SLC5A5GeneProductENSG00000105641 (Ensembl Human)
SLC5A6GeneProductENSG00000138074 (Ensembl Human)
SLC5A7GeneProductENSG00000115665 (Ensembl Human)
SLC5A8GeneProductENSG00000256870 (Ensembl Human)
SLC5A9GeneProductENSG00000117834 (Ensembl Human)
SLC6A11GeneProductENSG00000132164 (Ensembl Human)
SLC6A13GeneProductENSG00000010379 (Ensembl Human)
SLC6A14GeneProductENSG00000087916 (Ensembl Human)
SLC6A15GeneProductENSG00000072041 (Ensembl Human)
SLC6A16GeneProductENSG00000063127 (Ensembl Human)
SLC6A17GeneProductENSG00000197106 (Ensembl Human)
SLC6A18GeneProductENSG00000164363 (Ensembl Human)
SLC6A19GeneProductENSG00000174358 (Ensembl Human)
SLC6A1GeneProductENSG00000157103 (Ensembl Human)
SLC6A20GeneProductENSG00000163817 (Ensembl Human)
SLC6A2GeneProductENSG00000103546 (Ensembl Human)
SLC6A3GeneProductENSG00000142319 (Ensembl Human)
SLC6A4GeneProductENSG00000108576 (Ensembl Human)
SLC6A5GeneProductENSG00000165970 (Ensembl Human)
SLC6A6GeneProductENSG00000131389 (Ensembl Human)
SLC6A7GeneProductENSG00000011083 (Ensembl Human)
SLC6A8GeneProductENSG00000130821 (Ensembl Human)
SLC6A9GeneProductENSG00000196517 (Ensembl Human)
SLC7A11GeneProductENSG00000151012 (Ensembl Human)
SLC7A5GeneProductENSG00000103257 (Ensembl Human)
SLCO1B1GeneProductENSG00000134538 (Ensembl Human)
SLCO2B1GeneProductENSG00000137491 (Ensembl Human) inhibition
SMARCA1GeneProductENSG00000102038 (Ensembl Human)
SMC1AGeneProductENSG00000072501 (Ensembl Human)
SNAI2GeneProductENSG00000019549 (Ensembl Human)
SOD3GeneProductENSG00000109610 (Ensembl Human)
SP1GeneProductENSG00000185591 (Ensembl Human)
SPINK13GeneProductENSG00000214510 (Ensembl Human)
SPRY1GeneProductENSG00000164056 (Ensembl Human)
SQSTM1GeneProductENSG00000161011 (Ensembl Human)
SRC GeneProductENSG00000197122 (Ensembl Human)
SRC GeneProductENSG00000197122 (Ensembl Human)
SRCGeneProductENSG00000197122 (Ensembl Human)
SREBF1GeneProductENSG00000072310 (Ensembl Human)
SRGNGeneProductENSG00000122862 (Ensembl Human)
SRPX2GeneProductENSG00000102359 (Ensembl Human)
SRXN1GeneProductENSG00000172070 (Ensembl Human)
STAT3GeneProductENSG00000168610 (Ensembl Human)
STOMGeneProductENSG00000148175 (Ensembl Human)
SULT1A1GeneProductENSG00000196502 (Ensembl Human) during fasting
SULT2A1GeneProductENSG00000105398 (Ensembl Human)
Signal transductionPathway
TGFAGeneProductENSG00000163235 (Ensembl Human)
TGFB1GeneProductENSG00000105329 (Ensembl Human)
TGFB2GeneProductENSG00000092969 (Ensembl Human)
TGFBR2GeneProductENSG00000163513 (Ensembl Human)
TGFBR3GeneProductENSG00000069702 (Ensembl Human)
THBDGeneProductENSG00000178726 (Ensembl Human)
TNF GeneProductENSG00000232810 (Ensembl Human)
TNFAIP3GeneProductENSG00000118503 (Ensembl Human)
TNS4GeneProductENSG00000131746 (Ensembl Human)
TSC22D3GeneProductENSG00000157514 (Ensembl Human)
TXNGeneProductENSG00000136810 (Ensembl Human)
TXNRD1GeneProductENSG00000198431 (Ensembl Human)
TXNRD3GeneProductENSG00000197763 (Ensembl Human)
Transcription factorsPathway
TransportPathway
UGT1A1GeneProductENSG00000241635 (Ensembl Human)
UGT1A3GeneProductENSG00000243135 (Ensembl Human)
UGT1A4GeneProductENSG00000244474 (Ensembl Human)
UGT1A6GeneProductENSG00000167165 (Ensembl Human)
UGT1A7GeneProductENSG00000244122 (Ensembl Human)
UGT1A9GeneProductENSG00000241119 (Ensembl Human)
UGT2B4GeneProductENSG00000156096 (Ensembl Human)
UGT2B7GeneProductENSG00000171234 (Ensembl Human)
Unknown
VDRGeneProductENSG00000111424 (Ensembl Human)
ZIC2GeneProductENSG00000043355 (Ensembl Human)
bile acid conjugationPathway
fatty acid transportPathway
lipoprotein metabolismPathway
mitochondrial beta-oxidationPathway
mitochondrial omega-oxidationPathway
p23GeneProductENSG00000110958 (Ensembl Human)
peroxisomal beta-oxidationPathway

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2882"
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