BMP signaling pathway in eyelid development (Mus musculus)

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1Meibomian GlandConjunctival Cell FateEyelid ClosureTranslocation intoNucleusTransdifferentiation of MeibomianGland into Hair FolliclePeriderm MigrationEyelid ClosureConjunctiva Proliferation andPrecocious DifferentiationFgf10Fgfr2MEKK1Dkk2Smad4WntSmad1Sfrp1Foxc1BmpFoxc2Activin beta-BBmp4NotchTgfap-c-JunERKShhSmad5EgfrJNKPitx2


Description

No description

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Ontology Terms

 

Bibliography

  1. Huang J, Dattilo LK, Rajagopal R, Liu Y, Kaartinen V, Mishina Y, Deng CX, Umans L, Zwijsen A, Roberts AB, Beebe DC; ''FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate.''; Development, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123371view04:41, 19 July 2022EgonwMade two pathways clickable
117866view10:16, 23 May 2021EweitzModified title
111760view17:41, 4 September 2020DeSlChanged ID for Wnt Canonical Signaling to ID (iso name)
90081view05:16, 13 October 2016KhanspersModified title
88551view01:40, 11 August 2016AAR&CoAdded Data Node
88550view01:37, 11 August 2016AAR&CoEdited Labels
88548view01:34, 11 August 2016AAR&CoFixed Interactions
87671view08:55, 25 July 2016LindarieswijkOntology Term : 'signaling pathway pertinent to development' added !
85956view19:49, 21 June 2016AAR&CoAdjust canonical pathways
85946view19:07, 21 June 2016AAR&CoSignaling pathway nodes changed
85933view18:31, 21 June 2016AAR&CoFixed Unconnected Line
85932view18:30, 21 June 2016AAR&CoModified description
85867view23:19, 18 June 2016AAR&CoModified description
85866view21:46, 18 June 2016AAR&CoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Activin beta-BGeneProductENSMUSG00000037035 (Ensembl)
Bmp4GeneProductENSMUSG00000021835 (Ensembl)
BmpGeneProductENSMUSG00000022098 (Ensembl) BMP Not Specified
Dkk2GeneProductENSMUSG00000028031 (Ensembl)
ERKGeneProductENSMUSG00000063065 (Ensembl) ERK Not Specified
EgfrGeneProductENSMUSG00000020122 (Ensembl)
Fgf10GeneProductENSMUSG00000021732 (Ensembl)
Fgfr2GeneProductENSMUSG00000030849 (Ensembl)
Foxc1GeneProductENSMUSG00000050295 (Ensembl)
Foxc2GeneProductENSMUSG00000046714 (Ensembl)
JNKGeneProductENSMUSG00000020366 (Ensembl) JNK Not Specified
MEKK1GeneProductENSMUSG00000021754 (Ensembl)
NotchGeneProductENSMUSG00000026923 (Ensembl) Notch Not Specified
Pitx2GeneProductENSMUSG00000028023 (Ensembl)
Sfrp1GeneProductENSMUSG00000031548 (Ensembl)
ShhGeneProductENSMUSG00000002633 (Ensembl)
Smad1GeneProductENSMUSG00000031681 (Ensembl)
Smad4GeneProductENSMUSG00000024515 (Ensembl)
Smad5GeneProductENSMUSG00000021540 (Ensembl)
TgfaGeneProductENSMUSG00000029999 (Ensembl)
WntGeneProductENSMUSG00000022997 (Ensembl) Wnt Not Specified
p-c-JunGeneProductENSMUSG00000052684 (Ensembl)

Annotated Interactions

No annotated interactions

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