Benzene metabolism (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Rappaport SM, Kim S, Lan Q, Vermeulen R, Waidyanatha S, Zhang L, Li G, Yin S, Hayes RB, Rothman N, Smith MT; ''Evidence that humans metabolize benzene via two pathways.''; Environ Health Perspect, 2009 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	106161	view	12:05, 16 August 2019	MaintBot	HMDB identifier normalization
	97681	view	13:56, 1 June 2018	AMTan	Ontology Term : 'hepatocyte' added !
	94538	view	07:01, 21 September 2017	Egonw	Removed a redundant newline.
	89359	view	13:30, 7 September 2016	Riannefijten	added identifier vor microsomal epoxide hydrolase
	89346	view	09:52, 6 September 2016	Riannefijten	Modified description
	89345	view	09:52, 6 September 2016	Riannefijten	Modified description
	89344	view	04:35, 6 September 2016	Egonw	Used mim-conversion and annotated the catalysis with a mim approach too.
	89339	view	03:16, 5 September 2016	Egonw	Ontology Term : 'classic metabolic pathway' added !
	89338	view	03:16, 5 September 2016	Egonw	Ontology Term : 'phase I biotransformation pathway via cytochrome P450' added !
	89313	view	13:15, 1 September 2016	Riannefijten	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
1,2-Benzoquinone	Metabolite	HMDB12133 (HMDB)
Benzene dihydrodiol	Metabolite	418 (PubChem-compound)
Benzene diol epoxide	Metabolite
Benzene oxide	Metabolite	104944 (PubChem-compound)
Benzene	Metabolite	HMDB01505 (HMDB)
CYP2E1	GeneProduct	ENSG00000130649 (Ensembl)
Catechol	Metabolite	289 (PubChem-compound)
Dihydrodiol dehydrogenase	Protein	27294 (Entrez Gene)
Epoxide hydrolase	Protein
Glutathione S-transferase	GeneProduct	2944 (Entrez Gene)
Hydroquinone	Metabolite	HMDB02434 (HMDB)
MPO	GeneProduct	4353 (Entrez Gene)
NQO1	GeneProduct	ENSG00000181019 (Ensembl)
Oxepine	Metabolite	6451477 (PubChem-compound)
Phenol	Metabolite	HMDB00228 (HMDB)
S-Phenylmercapturic acid	Metabolite	HMDB42011 (HMDB)
p-benzoquinone	Metabolite	4650 (PubChem-compound)

Annotated Interactions

No annotated interactions