Histidine, purine, and pyrimidine superpathway (Saccharomyces cerevisiae)
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CTP
orotate
H+
THF
histidinal
NAD
D-erythro-imidazole-glycerol-phosphate
UDP
UTP
5’-phosphoribosyl-4-(N-
NH3
NAD
phosphoribosylformiminoAICAR-phosphate
H+
5-phosphoribosyl-n-formylglycineamidine
orotidine-5’-phosphate
5-phosphoribosylamine
HCO3
NAD
phosphoribosyl-ATP
2-oxoglutarate
5-phospho-ribosyl-glycineamide
carbamoyl-L-aspartate
H2O
H2O
L-aspartate
reduced thioredoxin
carbamoyl-phosphate
H2O
imidazole acetol-phosphate
AMP
UMP
THF
AMP
H2O
L-aspartate
H2O
H2O
CO2
H2O
phosphoribulosylformimino-AICAR-P
H2O
5’-phosphoribosyl-5-aminoimidazole
H+
H2O
H2O
deoxy-GTP
IMP
oxidized thioredoxin
phosphoribosyl-AMP
H2O
histidinol
H2O
H2O
reduced acceptor
fumerate
sucinocarboxamide)-5-aminoimidazole
phosphoribosyl-formamido-carboxamide
H2O
acceptor
reduced flavodoxin
phosphoribosyl-carboxy-aminoimidazole
H2O
dihydroorotate
AMP
H2O
CO2
5’-phosphoribosyl-N-formylglycineamide
oxidized flavodoxin
phosphate
GMP
ribose-5-phosphate
ATP
ADP
CDP
phosphate
dGDP
L-glutamate
pyrophosphate
phosphate
L-glutamine
URA2
ATP
GUK1
URA7
phosphate
L-histidinol-phosphate
L-glutamine
pyrophosphate
L-glutamate
L-glutamate
ADP
xanthosine-5-phosphate
HIS1
URA8
HIS4
pyrophosphate
URA5
ADE16
ADP
ADE5,7
ADP
PRS1
RNR4
RNR1
phosphate
ATP
ADE17
ATP
ADE2
NADH
ATP
HIS4
URA10
phosphate
PRS3
ADP
pyrophosphate
ADP
ADE1
IMD2
ATP
L-histidine
phosphate
L-glycine
ATP
phosphate
ADE8
ADE6
RNR3
phosphate
L-glutamine
URA3
10-formyl-THF
ATP
GDP
PRS2
HIS5
phosphate
PRPP
ATP
ADP
2 ADP
YNK1
ADP
URA4
HIS4
ADE4
GTP
ATP
ADE16
L-glutamate
IMD3
ADE17
L-glutamate
ATP
pyrophosphate
ATP
ADP
PRS5
GUA1
L-glutamine
HIS2
L-glutamate
ATP
ATP
L-glutamate
YNK1
NADH
NADH
ATP
ADE5,7
RNR2
10-formyl-THF
ADE13
PRS4
URA1
AICAR
ADP
2 ATP
ADP
HIS3
URA2
L-glutamine
ATP
URA6
HIS4
IMD4
HIS6
L-glutamine
ADP
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
Try the New WikiPathways
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the new wikipathways.org
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
''Histidine, purine, and pyrimidine superpathway''; YeastPathways,
History
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Compare
Revision
Action
Time
User
Comment
135544
view
20:00, 23 September 2024
Khanspers
Modified description
135448
view
21:58, 5 September 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
135447
view
21:58, 5 September 2024
Khanspers
removed GenMAPP comments
135446
view
21:57, 5 September 2024
Khanspers
135445
view
21:56, 5 September 2024
Khanspers
lit ref
135314
view
00:05, 17 August 2024
Khanspers
interactions
122754
view
05:17, 10 May 2022
Egonw
Added identifiers to water nodes
117345
view
11:53, 20 May 2021
Eweitz
Modified title
107259
view
14:35, 17 September 2019
MaintBot
ChEBI identifier normalization
94664
view
13:18, 4 October 2017
DeSl
Changed ribose-5-P label to D-ribose-5-P
94663
view
13:17, 4 October 2017
DeSl
Connected all lines, changed all textlabels to metabolite nodes, connected all genes to the lines.
93079
view
09:22, 28 July 2017
Elisa
Fixed some of the unconnected interactions (left side of the pathway).
93011
view
14:46, 24 July 2017
DeSl
Changed wrong CAS number (salt) for correct ChEBI ID
85638
view
16:11, 4 June 2016
Egonw
Fixed the CAS number.
71897
view
10:35, 22 October 2013
Mkutmon
changed AICAR from Unknown to Metabolite
70270
view
21:50, 15 July 2013
MaintBot
updated to 2013 schema
69872
view
18:00, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
67670
view
11:47, 26 June 2013
Ddigles
Ontology Term : 'nucleotide metabolic pathway' added !
41803
view
04:48, 2 March 2011
MaintBot
Removed redundant pathway information and comments
21558
view
11:32, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:Superpathway of Histidine Purine and Pyrimidine Biosynthesis]] moved to [[Pathway:WP416]]: Moved to stable identifier
12861
view
08:06, 17 May 2008
MaintBot
automated metabolite conversion
8948
view
14:13, 7 January 2008
MaintBot
Added to category $category
8946
view
14:13, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
10-formyl-THF
Metabolite
2800-34-2 (CAS)
2 ADP
Metabolite
58-64-0 (CAS)
2 ATP
Metabolite
1927-31-7 (CAS)
ADE13
GeneProduct
S000004351 (SGD)
ADE16
GeneProduct
S000004018 (SGD)
ADE17
GeneProduct
S000004727 (SGD)
ADE1
GeneProduct
S000000070 (SGD)
ADE2
GeneProduct
S000005654 (SGD)
ADE4
GeneProduct
S000004915 (SGD)
ADE5,7
GeneProduct
S000003203 (SGD)
ADE6
GeneProduct
S000003293 (SGD)
ADE8
GeneProduct
S000002816 (SGD)
ADP
Metabolite
58-64-0 (CAS)
AICAR
Metabolite
3031-94-5 (CAS)
ATP
Metabolite
1927-31-7 (CAS)
CDP
Metabolite
63-38-7 (CAS)
GDP
Metabolite
146-91-8 (CAS)
GMP
Metabolite
85-32-5 (CAS)
GTP
Metabolite
2564-35-4 (CAS)
GUA1
GeneProduct
S000004830 (SGD)
GUK1
GeneProduct
S000001550 (SGD)
HIS1
GeneProduct
S000000857 (SGD)
HIS2
GeneProduct
S000001921 (SGD)
HIS3
GeneProduct
S000005728 (SGD)
HIS4
GeneProduct
S000000535 (SGD)
HIS5
GeneProduct
S000001378 (SGD)
HIS6
GeneProduct
S000001282 (SGD)
IMD2
GeneProduct
S000001259 (SGD)
IMD3
GeneProduct
S000004424 (SGD)
IMD4
GeneProduct
S000004520 (SGD)
L-glutamate
Metabolite
56-86-0 (CAS)
L-glutamine
Metabolite
56-85-9 (CAS)
L-glycine
Metabolite
56-40-6 (CAS)
L-histidine
Metabolite
71-00-1 (CAS)
L-histidinol-phosphate
Metabolite
25679-93-0 (CAS)
NADH
Metabolite
53-84-9 (CAS)
PRPP
Metabolite
97-55-2 (CAS)
PRS1
GeneProduct
S000001664 (SGD)
PRS2
GeneProduct
S000000901 (SGD)
PRS3
GeneProduct
S000001003 (SGD)
PRS4
GeneProduct
S000000164 (SGD)
PRS5
GeneProduct
S000005422 (SGD)
RNR1
GeneProduct
S000000872 (SGD)
RNR2
GeneProduct
S000003563 (SGD)
RNR3
GeneProduct
S000001328 (SGD)
RNR4
GeneProduct
S000003412 (SGD)
URA10
GeneProduct
S000004884 (SGD)
URA1
GeneProduct
S000001699 (SGD)
URA2
GeneProduct
S000003666 (SGD)
URA3
GeneProduct
S000000747 (SGD)
URA4
GeneProduct
S000004412 (SGD)
URA5
GeneProduct
S000004574 (SGD)
URA6
GeneProduct
S000001507 (SGD)
URA7
GeneProduct
S000000135 (SGD)
URA8
GeneProduct
S000003864 (SGD)
YNK1
GeneProduct
S000001550 (SGD)
dGDP
Metabolite
28862 (ChEBI)
phosphate
Metabolite
14265-44-2 (CAS)
pyrophosphate
Metabolite
2466-09-3 (CAS)
ribose-5-phosphate
Metabolite
3615-55-2 (CAS)
xanthosine-5-phosphate
Metabolite
523-98-8 (CAS)
Annotated Interactions
No annotated interactions
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Discussion
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