Non-canonical Wnt pathway (Danio rerio)
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Khanspers
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1
Cytoskeleton
FGF
X
wnt hompagge_ZF
pcp pathway
fgf
actin polymerization
?
BMP
Ca-pathway
other responsive genes
laminopoda
PDGF
nodal
organizer
ventral genes
catenin-beta 2
gsc
fgf8
wnt8a
bmp4
mapk8b
cfl1
wnt16
wnt5b
c-myc
prkcbb
mapk9
LRP5
vangl1
tcf4
stat3
chd
Sp5l
rfzd8b
dvl3
mkp3
vangl2
axin1
mapk10
groucho3
RhoAd
rac1a
ptpn11a
celsr1b
rac1
cki
wnt11
dvl3
abi1a
E12 / tcf3
celsr1a
spry4
wnt2b
prickle1a
rock2b
tbx16 / spt
tbx6
axin2
Ca2+
ephin B1
icat
gelsolin
pea
fzd8a
wnt10b
capga
csk
eve1
wnt4b
has2
src
daam1
flh
fzd7a
abi1a
vox
mitfa
cfl2
c-jun
knypek
catenin-beta 1
lef
fzd4
Tak1
cdx4
gsk3b
csk
pfn2
sfzd1
evla
wnt4a
RhoAa
otx1
gata2
sp5a
pak1
fzd10
fzd9
actr2a
oep
fzd8c
bmp2b
wnt8b
tcf3 / tcf7l1a
sqt
vent
wnt2
cap1
tcl
dvl2
erm
ERK2 / MAPK1
GBP
ERK1 / MAPK3
frzb
fzd7b
evlb
wnt3l
APC
pfn2l
fzd3
cdc42l2
nap1l1
RhoAb
camk2d
fgf3
wnt1
cdc42l
rac3
limk2
otx2
prickle2
actr3
quo
rac2
lim1
dharma/boz
rhoca
capgb
Yes1
ntl
sfzd5
rock2a
NLK
wnt7a
prkcbb
cdc42
fyna
wif1
limk1
dact2 / drapper
cyclin D1
tmsb4x
fz12
camk1g
spry2
dvl2
prickle1
groucho1
wnt5a
groucho2
fzd10
wnt10a
wnt7
ved
fzd2
smo
boz
rhoac
tcf3b / tcf7l1b
rock1
dia1
wnt11r
rac1b
rac1l
actr2b
Description
No description
Comments
GenMAPP notes
* = gene not present in GenMAPP gene database
GenMAPP remarks
# = gene not represented in Agilent zebrafish 22K oligo set
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Quality Tags
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Saving...
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Bibliography
Krens SF, Corredor-Adamez M, He S, Snaar-Jagalska BE, Spaink HP; ''ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis.''; BMC Genomics, 2008
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
127751
view
11:25, 2 December 2023
Egonw
ChEBI id for Ca2+ instead of the "Ca" atom
116895
view
11:22, 15 May 2021
Eweitz
Modified title
95547
view
14:26, 22 December 2017
DeSl
COnnected unconnected lines.
95510
view
00:48, 19 December 2017
Khanspers
fixed two more xrefs
95509
view
00:44, 19 December 2017
Khanspers
removed GenMAPP comments
95508
view
00:43, 19 December 2017
Khanspers
fixed unconnected xrefs and lines
84702
view
21:39, 15 March 2016
Khanspers
Quick edit to datanode annotation or property
74203
view
07:25, 5 April 2014
Egonw
Removed a data source where no ID was given.
71974
view
00:24, 24 October 2013
MaintBot
Updated data sources
70259
view
21:44, 15 July 2013
MaintBot
updated to 2013 schema
70194
view
02:00, 13 July 2013
AlexanderPico
Modified title
67517
view
11:20, 26 June 2013
Ddigles
Ontology Term : 'non-canonical Wnt signaling pathway' added !
62784
view
16:30, 2 May 2013
MaintBot
updated uniprot data source
40786
view
22:15, 1 March 2011
MaintBot
Removed redundant pathway information and comments
21131
view
11:30, 14 November 2008
MaintBot
[[Pathway:Danio rerio:Wnt Signaling noncanonical]] moved to [[Pathway:WP215]]: Moved to stable identifier
16302
view
20:47, 17 June 2008
Khanspers
[[Pathway:Danio rerio:Dr Wnt-signaling noncanonical]] moved to [[Pathway:Danio rerio:Wnt Signaling noncanonical]]: Removed species code prefix from pathway name
14280
view
07:48, 22 May 2008
SFGKrens
Modified categories
14041
view
08:12, 21 May 2008
SFGKrens
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
APC
GeneProduct
386762 (Entrez Gene)
Ca2+
Metabolite
CHEBI:22984 (ChEBI)
E12 / tcf3
GeneProduct
30310 (Entrez Gene)
ERK1 / MAPK3
GeneProduct
399480 (Entrez Gene)
ERK2 / MAPK1
GeneProduct
360144 (Entrez Gene)
GBP
GeneProduct
30719 (Entrez Gene)
LRP5
GeneProduct
554087 (Entrez Gene)
NLK
GeneProduct
405892 (Entrez Gene)
Nem like kinase
RhoAa
GeneProduct
406411 (Entrez Gene)
RhoAb
GeneProduct
336001 (Entrez Gene)
RhoAd
GeneProduct
436718 (Entrez Gene)
Sp5l
GeneProduct
324261 (Entrez Gene)
Tak1
GeneProduct
553788 (Entrez Gene)
Yes1
GeneProduct
407620 (Entrez Gene)
abi1a
GeneProduct
ENSDARG00000010155 (Ensembl)
actr2a
GeneProduct
ENSDARG00000052438 (Ensembl)
actr2b
GeneProduct
ENSDARG00000070076 (Ensembl)
actr3
GeneProduct
ENSDARG00000091138 (Ensembl)
axin1
GeneProduct
57931 (Entrez Gene)
masterblind
axin2
GeneProduct
58080 (Entrez Gene)
bmp2b
GeneProduct
30632 (Entrez Gene)
bmp4
GeneProduct
30612 (Entrez Gene)
boz
GeneProduct
30170 (Entrez Gene)
c-jun
GeneProduct
335916 (Entrez Gene)
c-myc
GeneProduct
30686 (Entrez Gene)
camk1g
GeneProduct
335654 (Entrez Gene)
camk2d
GeneProduct
436815 (Entrez Gene)
cap1
GeneProduct
Dr.6923 (UniGene)
capga
GeneProduct
ENSDARG00000035560 (Ensembl)
capgb
GeneProduct
ENSDARG00000099672 (Ensembl)
catenin-beta 1
GeneProduct
30265 (Entrez Gene)
âcatenin (cadherin-associated protein), beta 1 â
catenin-beta 2
GeneProduct
324004 (Entrez Gene)
âcatenin (cadherin-associated protein), beta 2â
cdc42
GeneProduct
336839 (Entrez Gene)
cdc42l2
GeneProduct
556226 (Entrez Gene)
cdc42l
GeneProduct
ENSDARG00000040158 (Ensembl)
cdx4
GeneProduct
30330 (Entrez Gene)
celsr1a
GeneProduct
ENSDARG00000069185 (Ensembl)
celsr1b
GeneProduct
ENSDARG00000058259 (Ensembl)
cfl1
GeneProduct
ENSDARG00000021124 (Ensembl)
cfl2
GeneProduct
ENSDARG00000014106 (Ensembl)
chd
GeneProduct
30161 (Entrez Gene)
cki
GeneProduct
30328 (Entrez Gene)
csk
GeneProduct
ENSDARG00000067996 (Ensembl)
cyclin D1
GeneProduct
30222 (Entrez Gene)
daam1
GeneProduct
378457 (Entrez Gene)
dact2 / drapper
GeneProduct
337795 (Entrez Gene)
âdapper homolog 2, antagonist of beta-cateninâ
dharma/boz
GeneProduct
30170 (Entrez Gene)
dia1
GeneProduct
336553 (Entrez Gene)
dvl2
GeneProduct
323630 (Entrez Gene)
dvl3
GeneProduct
80972 (Entrez Gene)
ephin B1
GeneProduct
114377 (Entrez Gene)
erm
GeneProduct
30452 (Entrez Gene)
eve1
GeneProduct
30335 (Entrez Gene)
evla
GeneProduct
ENSDARG00000035650 (Ensembl)
evlb
GeneProduct
ENSDARG00000099720 (Ensembl)
fgf3
GeneProduct
30549 (Entrez Gene)
fgf8
GeneProduct
30538 (Entrez Gene)
flh
GeneProduct
30260 (Entrez Gene)
frzb
GeneProduct
30119 (Entrez Gene)
fyna
GeneProduct
ENSDARG00000011370 (Ensembl)
fz12
GeneProduct
30275 (Entrez Gene)
fzd10
GeneProduct
30366 (Entrez Gene)
fzd10
GeneProduct
ENSDARG00000068213 (Ensembl)
fzd2
GeneProduct
30370 (Entrez Gene)
fzd3
GeneProduct
30371 (Entrez Gene)
fzd4
GeneProduct
30363 (Entrez Gene)
fzd7a
GeneProduct
ENSDARG00000060004 (Ensembl)
fzd7b
GeneProduct
30412 (Entrez Gene)
fzd8a
GeneProduct
58073 (Entrez Gene)
fzd8c
GeneProduct
30364 (Entrez Gene)
fzd9
GeneProduct
58023 (Entrez Gene)
gata2
GeneProduct
30480 (Entrez Gene)
gelsolin
GeneProduct
321099 (Entrez Gene)
groucho1
GeneProduct
30205 (Entrez Gene)
groucho2
GeneProduct
30206 (Entrez Gene)
groucho3
GeneProduct
83411 (Entrez Gene)
gsc
GeneProduct
30212 (Entrez Gene)
gsk3b
GeneProduct
30654 (Entrez Gene)
has2
GeneProduct
ENSDARG00000036987 (Ensembl)
icat
GeneProduct
58117 (Entrez Gene)
beta-catenin-interacting protein
knypek
GeneProduct
118437 (Entrez Gene)
lef
GeneProduct
30701 (Entrez Gene)
lim1
GeneProduct
30463 (Entrez Gene)
limk1
GeneProduct
735292 (Entrez Gene)
limk2
GeneProduct
ENSDARG00000005104 (Ensembl)
mapk10
GeneProduct
ENSDARG00000102730 (Ensembl)
mapk8b
GeneProduct
ENSDARG00000009870 (Ensembl)
mapk9
GeneProduct
ENSDARG00000077364 (Ensembl)
mitfa
GeneProduct
30080 (Entrez Gene)
mkp3
GeneProduct
353314 (Entrez Gene)
nap1l1
GeneProduct
ENSDARG00000101813 (Ensembl)
ntl
GeneProduct
30399 (Entrez Gene)
oep
GeneProduct
30304 (Entrez Gene)
otx1
GeneProduct
30500 (Entrez Gene)
otx2
GeneProduct
30501 (Entrez Gene)
pak1
GeneProduct
373103 (Entrez Gene)
pea
GeneProduct
30700 (Entrez Gene)
pfn2
GeneProduct
ENSDARG00000003952 (Ensembl)
pfn2l
GeneProduct
ENSDARG00000012682 (Ensembl)
prickle1
GeneProduct
368249 (Entrez Gene)
prickle1a
GeneProduct
ENSDARG00000040649 (Ensembl)
prickle2
GeneProduct
368250 (Entrez Gene)
prkcbb
GeneProduct
ENSDARG00000022254 (Ensembl)
ptpn11a
GeneProduct
ENSDARG00000020334 (Ensembl)
quo
GeneProduct
321031 (Entrez Gene)
rac1
GeneProduct
Dr.4711 (UniGene)
rac1a
GeneProduct
ENSDARG00000074849 (Ensembl)
rac1b
GeneProduct
ENSDARG00000087954 (Ensembl)
rac1l
GeneProduct
ENSDARG00000054649 (Ensembl)
rac2
GeneProduct
415151 (Entrez Gene)
rac3
GeneProduct
437027 (Entrez Gene)
rfzd8b
GeneProduct
58072 (Entrez Gene)
rhoac
GeneProduct
ENSDARG00000099709 (Ensembl)
rhoca
GeneProduct
ENSDARG00000021309 (Ensembl)
rock1
GeneProduct
ENSDARG00000058993 (Ensembl)
rock2a
GeneProduct
ENSDARG00000017500 (Ensembl)
rock2b
GeneProduct
ENSDARG00000004877 (Ensembl)
sfzd1
GeneProduct
402843 (Entrez Gene)
secreted frizzled-related protein
sfzd5
GeneProduct
117510 (Entrez Gene)
secreted frizzled-related protein
smo
GeneProduct
30225 (Entrez Gene)
sp5a
GeneProduct
ENSDARG00000076571 (Ensembl)
spry2
GeneProduct
335098 (Entrez Gene)
spry4
GeneProduct
114437 (Entrez Gene)
sqt
GeneProduct
30153 (Entrez Gene)
src
GeneProduct
ENSDARG00000008107 (Ensembl)
stat3
GeneProduct
30767 (Entrez Gene)
tbx16 / spt
GeneProduct
30264 (Entrez Gene)
tbx6
GeneProduct
30254 (Entrez Gene)
tcf3 / tcf7l1a
GeneProduct
30523 (Entrez Gene)
tcf3b / tcf7l1b
GeneProduct
30556 (Entrez Gene)
tcf4
GeneProduct
30510 (Entrez Gene)
tcl
GeneProduct
386615 (Entrez Gene)
secreted frizzled-related protein
tmsb4x
GeneProduct
ENSDARG00000077777 (Ensembl)
vangl1
GeneProduct
ENSDARG00000004305 (Ensembl)
vangl2
GeneProduct
ENSDARG00000027397 (Ensembl)
ved
GeneProduct
368201 (Entrez Gene)
vent
GeneProduct
64810 (Entrez Gene)
vox
GeneProduct
64807 (Entrez Gene)
wif1
GeneProduct
30476 (Entrez Gene)
wnt inhibitory factor 1
wnt10a
GeneProduct
30171 (Entrez Gene)
wnt10b
GeneProduct
30308 (Entrez Gene)
wnt11
GeneProduct
ENSDARG00000004256 (Ensembl)
silberblick
wnt11r
GeneProduct
ENSDARG00000014796 (Ensembl)
wnt1
GeneProduct
30128 (Entrez Gene)
wnt16
GeneProduct
404628 (Entrez Gene)
wnt2
GeneProduct
30127 (Entrez Gene)
wnt2b
GeneProduct
359837 (Entrez Gene)
wnt3l
GeneProduct
60632 (Entrez Gene)
wnt4a
GeneProduct
30123 (Entrez Gene)
wnt4b
GeneProduct
57928 (Entrez Gene)
wnt5a
GeneProduct
ZDB-GENE-060328-3 (ZFIN)
wnt5b
GeneProduct
30105 (Entrez Gene)
wnt7
GeneProduct
60633 (Entrez Gene)
wnt7a
GeneProduct
565714 (Entrez Gene)
wnt8a
GeneProduct
30122 (Entrez Gene)
wnt8b
GeneProduct
30144 (Entrez Gene)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions