Gluconeogenesis (Saccharomyces cerevisiae)

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1[CO2]Dihydroxy-acetone-phosphateD-Fructose-1,6-bisphosphateH2O[CO2]3-phosphoglycerateH+NADNADH+pyruvateH2OOxaloacetic acid2-phosphoglycerateNADfructose-6-phosphateFBP1phosphateENO1ATPMDH1MDH3FBA1phosphatePGI1GPM1ADPPCK1PGK1NADHphosphoenolpyruvateTDH2ERR1TDH1ENO2YMR323WNADHglucose-6-phosphateATPNADHglyceraldehyde-3-phosphatemalateADPMAE1TDH33-phospho-D-glyceroyl-phosphateGPM3ERR2MDH2


Description

This is the proposed pathway for p-hydroxybenzoate biosynthesis in S. cerevisiae based on genetic studies and incorporation of radiolabeled intermediates.(CITS: [11583838]) SOURCE: SGD pathways, http://pathway.yeastgenome.org/server.html

Comments

GenMAPP remarks 

Based on http://pathway.yeastgenome.org/biocyc/

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Quality Tags

Ontology Terms

 

Bibliography

  1. Klein CJ, Olsson L, Nielsen J; ''Glucose control in Saccharomyces cerevisiae: the role of Mig1 in metabolic functions.''; Microbiology, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
102416view09:55, 23 December 2018EgonwReplaced a deleted CAS number with the active one.
96396view09:59, 12 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
94080view12:18, 18 August 2017DeSlConnected last line.
94077view15:30, 17 August 2017DeSlAdded last 2 missing IDs (fructose-1,6-bisphosphate and NAD).
94076view15:27, 17 August 2017DeSlAnnotated several nodes; changed ID for fructose+glucose-6-phosphate (from open to closed form)
94075view15:14, 17 August 2017DeSlChanged textlabels to metabolite nodes, connected all lines.
89686view07:37, 25 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
69762view11:08, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69650view20:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
67286view10:31, 26 June 2013Christine ChichesterOntology Term : 'gluconeogenesis pathway' added !
58990view19:35, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41889view04:53, 2 March 2011MaintBotRemoved redundant pathway information and comments
36614view22:30, 9 April 2010MaintBotDescription and bibliography added from SGD
29889view11:15, 9 June 2009Thomasupdated ensembl references
21009view11:30, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Gluconeogenesis]] moved to [[Pathway:WP156]]: Moved to stable identifier
12710view07:59, 17 May 2008MaintBotautomated metabolite conversion
10993view20:21, 2 March 2008MaintBotyeast id converter
8726view14:07, 7 January 2008MaintBotAdded to category $category
8724view14:07, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-phosphoglycerateMetaboliteCHEBI:17835 (ChEBI)
3-phospho-D-glyceroyl-phosphateMetabolite38168-82-0 (CAS)
3-phosphoglycerateMetaboliteCHEBI:17794 (ChEBI)
ADPMetabolite58-64-0 (CAS)
ATPMetabolite1927-31-7 (CAS)
D-Fructose-1,6-bisphosphateMetaboliteCHEBI:40595 (ChEBI)
Dihydroxy-acetone-phosphateMetaboliteCHEBI:16108 (ChEBI)
ENO1GeneProductENOS0000 (SGD)
ENO2GeneProductENOS0000 (SGD)
ERR1GeneProductERRS0000 (SGD)
ERR2GeneProductS000006202 (SGD)
FBA1GeneProductFBAS0000 (SGD)
FBP1GeneProductFBPS0000 (SGD)
GPM1GeneProductGPMS0000 (SGD)
GPM3GeneProductGPMS0000 (SGD)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
MAE1GeneProductS000001512 (SGD)
MDH1GeneProductS000001568 (SGD)
MDH2GeneProductS000005486 (SGD)
MDH3GeneProductS000002236 (SGD)
NADMetaboliteCHEBI:13389 (ChEBI)
NADHMetabolite53-84-9 (CAS)
Oxaloacetic acidMetaboliteCHEBI:30744 (ChEBI)
PCK1GeneProductS000001805 (SGD)
PGI1GeneProductPGIS0000 (SGD)
PGK1GeneProductPGKS0000 (SGD)
TDH1GeneProductTDHS0000 (SGD)
TDH2GeneProductTDHS0000 (SGD)
TDH3GeneProductTDHS0000 (SGD)
YMR323WGeneProductYMR323S0000 (Ensembl)
[CO2]MetaboliteCHEBI:16526 (ChEBI)
fructose-6-phosphateMetabolite15648788 (PubChem-compound)
glucose-6-phosphateMetaboliteCHEBI:75150 (ChEBI)
glyceraldehyde-3-phosphateMetabolite591-57-1 (CAS)
malateMetabolite617-48-1 (CAS)
phosphateMetabolite14265-44-2 (CAS)
phosphoenolpyruvateMetabolite138-08-9 (CAS)
pyruvateMetaboliteCHEBI:15361 (ChEBI)

Annotated Interactions

No annotated interactions
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