Nuclear receptors meta-pathway (Homo sapiens)

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6, 49CAR/PXR LigandCAR target genes2GCLMCYP2A6ESR1ME1Co-activatorsFKBP5SLC7A11G6PDAGERNFKB2RGS2NR1H4UGT2B7POU5F1ANKRD1GSTT2FGD4DegradationGGT1EPHA2CES1SLCO2B1FTLABCC2ETNK2PRRG4GPX2PLK2CYP3A7CDC42EP3ALOX5APGPX3SULT2A1Cell proliferationand apoptosisCYP4A11TGFB2ALDH3A1NCOA1CYP2A6MYOFCYP2B6CDKN1CDNAJC7FGFBP1bile acidconjugationGCLCNR3C1SLC2A3ABCB11SLC26A2DNAJC15OtherGSTP1SP1THBDTGFBR2UGT1A7SLC2A8IL12AUGT1A6SRCSLC2A9MGST1SULT1A1HBEGFABCB4SULT2A1TNS4SLC2A14EP300SNAI2PPARAFTH1NAV3CYP4A11PTGS2CYP7A1SRGNSLC10A1CYP3A4MGST2ZIC2CAP2SLC2A7SLC7A5NCOA2CES5AUGT1A4ABCC3PDE4BCYP3A4EGR1SRXN1HGFSEC14L1SLC2A6SPRY1SQSTM1SLC2A11PCK1GSTA1CBR3AMIGO2SMARCA1Cell proliferationand differentiationFGF13UGT1A4JUNSLC2A4JUNBIRC3UGT1A9CCL2NR0B2CYP2C9SLC2A2GADD45BIP6K3SLC27A5PGDSTAT3NR0B2UGT1A3BAATCES4ACES2UGT1A4CYP1A2CYP3A4PPARGC1ACCL20Drug and steroidmetabolismUGT1A1TNFAIP3CYP1A1CYP2B6HSP90AA1ARL5BTGFAPPARAGPAMUGT1A9TGFBR3GPR153IL12BPDK4PDGFBIRS2Bile acid &xenobiotics transportJUNBACOX1CYP7A1PPARGC1ASERTAD2TGFB1CES3TXNGSTA4PPP2R4SERPINB2EDN2IL1BALAS1HSPA1ACYP2C19MGAMPMP2MAFGIFNGSULT2A1TXNRD3SOD3DNAJB1SLC2A12LRRC8ACES3UGT1A7S100PSTOMSREBF1PPP1R14CGSTA3SLC2A5TGFB1BIRC2GCC1ABCC3ABHD2InflammationGPR115NCOA6Bile acidneosynthesisSP1UGT1A1CXCR7SERPINB9TranscriptionfactorsSLC2A13SLC19A2UGT1A9NRG1RXRAPOLKNR0B2ABCC4TranscriptionfactorsDNERSPINK13SMC1AABCG5CBR1NQO1MGST3EPHA3PRDX6ACAA1B3GNT5SERPINA1KAT2BUGT2B4UGT1A3KEAP1SLC2A1ENC1ABCG8NFE2L2HMOX1SCNN1AABCC2PRDX1ANGPTL4PPARDSDPRGSTA2FGF19UGT1A6AKAP13PTGR1ABCB1CYP2A6CYP1B1HSP90AA1TSC22D3MFGE8ADH7NR1H3FASNCPEB4IL11EHHADHMetabolismHSP90AB1EPB41L4BCYP7A1GSTA2CUL1Phase 2metabolismMT1IPIL17BAntioxidantproteinsGSTA5GSRKTN1TXNRD1GSTT1UGT1A3CYP3A5ABCC5MAFFBLVRBCYP8B1NR1I3SLC2A10BHLHE407243635284537363630NR1I373642521281324413628124181236242334283616, 483743375347361283712373837357292837354239729285423633363635436313637365293613LigandDNAJC7HSP90AA1CoregulatorsGenesTATA boxPBREMRXRANR1I3LigandCo-activatorsNCOA1EGFR pathwayEP300UGT1A620, 28, 36AHRRSRC7CDKN1BAIP7CYP1B14, 7, 20, 28, 42UGT1A120, 28, 36ALDH3A142GSTA220, 28AHRJUND27NQO120, 28IGFBP119NFE2L2BAX207JUN17CYP1A2EGFR4, 7, 20, 28, 42HSP90AA1TNFPTGES3IL214HES1ARNT50CDC37CYP1A14, 7, 20, 28, 42AHRARNTAIPSRCSRCCDC37AHRARNTAHRLigandLigandLigandXREGenesTATA boxUGT1A9Hepatocyteproliferation21, 36NR1H321SCP2CPT1A2121APOC321FABP121CCND1PLTP2121DBIAPOA22121CPT221APOA1CYP4A1121ACADM2121CDK4CYP7A12121MYC21mitochondrialomega-oxidationSLC27A121Cholesterolcatabolismperoxisomalbeta-oxidationKLK1521APOA521CDK121CYP8B1PPAR alpha ligand21PPARAGenesTATA boxPPREPPARARXRALigandlipoproteinmetabolismfatty acidtransportmitochondrialbeta-oxidationPXR target genes5, 15SLCO1B115HSP90AA1NR1I2SRPX2NCOA3FOXO111CYP4F12CYP3A41528UGT1A1DNAJC715ABCC415NRIP1UnknownCYP2B6GSTA228PSMC515PPARGC1ANCOA1NCOA2ABCB1NR1I215LigandCoregulatorsGenesTATA boxXRERXRANR1I2LigandAhR LigandCo-activatorsGenesTATA boxNR1I3NR1I2NR3C1RXRA16, 48NR1I3NR1I2NR3C1HSP90AA1GR ligandp23HSP90AA1p23NR3C1HSP90AA126, 33p23NR3C133LigandNR3C133LigandLigandLigandNR3C1NR3C1LigandLigandGREGenesTATA boxNR3C1NR3C1LigandLigandnGRECoregulatorsGR inhibitorytarget genesLXR ligandNR1H3LigandRXRA16, 48PTGES3RXRA16, 48NR1H3CYP2B637CYP2C937GenesTATA boxVDREVDR target genesVDR32, 33LigandRXRACYP3A437VDRVDR ligandRXRAVDRLigandER ligandESR1ESR1LigandLigandGenesTATA boxEREESR1LigandESR1LigandESR138ESR1ESR1LigandLigandCoregulatorsER target genes44GenesTATA boxNR1H3LigandLXRERXRALXR target genes16, 48FXR ligandNR1H423RXRALigandGenesTATA boxNR1H4RXRA23LigandFXREBile aciddetoxification29NR1H423LigandUGT1A4UGT1A636UGT1A936UGT1A33636CYP2C928CYP3A528CYP2C1928SULT2A1ABCC21ABCC337EHHADH37FOXO135Inflammation1125Growth andapoptosis25SignaltransductionOther2525InflammationGrowth andapoptosis25Signaltransduction25Metabolism2525TransportOther25Nuclearreceptors25FXR Target genesOtherGR stimulatorytarget genesMulti-drugresistanceDrug and steroidmetabolismPhase 2metabolismMulti-drugresistanceOtherOtherPhase 2metabolismDrug and steroidmetabolismPhase 2metabolismOtherDrug and steroidmetabolismMulti-drugresistanceTranscriptionfactorsOtherDrug and steroidmetabolismTranscriptionfactorsOtherDrug and steroidmetabolismPPAR alphatarget genesAhR target genesGenesTATA boxRXRALigandARENRF2 targetgenesOther34Phase 1proteinsPhase 2proteins3434GSTM5GSTM1GSTM2GSTM3GSTM4TransportSLC5A234SLC5A1SLC5A4SLC5A10SLC5A9SLC5A6SLC5A11SLC5A12SLC5A3SLC5A7SLC5A8SLC5A5SLC6A2SLC6A1SLC6A4SLC6A11SLC6A9SLC6A6SLC6A13SLC6A14SLC6A3SLC6A7SLC6A8SLC6A5SLC6A16SLC6A15SLC6A18SLC6A20SLC6A17SLC6A19SLC39A2SLC39A1SLC39A4SLC39A10SLC39A9SLC39A6SLC39A11SLC39A12SLC39A3SLC39A7SLC39A8SLC39A5SLC39A13SLC39A14Growth factorsand receptors34NFE2L2NRF2 ligandKEAP1NFE2L2LigandNFE2L2NFE2L2SCD


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Bibliography

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History

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CompareRevisionActionTimeUserComment
126680view16:51, 11 June 2023EgonwFixed character encoding issues
126012view11:37, 26 March 2023EgonwWrong ligand term
125859view10:46, 13 March 2023DeSlFixed last 'ligand' classified as protein
125858view10:44, 13 March 2023DeSlResolved typo in description
125857view10:43, 13 March 2023DeSlRemoved empty comment from Description
125856view10:42, 13 March 2023DeSlConnected unconnected line
125855view10:41, 13 March 2023DeSlConverted textLabels 'ligand; to DataNode Metabolite, with ChEBI annotation; changed two protein datanodes to metaboliute for ligand.
125833view07:00, 13 March 2023EgonwAdded ChEBI identifiers for ligands
120815view15:30, 11 January 2022SusanOntology Term : 'transcription factor mediated signaling pathway' added !
117808view14:40, 22 May 2021EweitzModified title
115341view14:20, 14 February 2021EgonwMade more pathways clickable
103038view11:54, 2 February 2019MaintBotReplaced an outdated Ensembl identifiers with the new one.
97489view13:23, 23 May 2018Fehrhartlayout
97488view13:17, 23 May 2018Fehrhartadded annotations
97487view13:08, 23 May 2018Fehrhartadded annotations
97484view12:58, 23 May 2018FehrhartModified description
97483view12:56, 23 May 2018Fehrhartadded annotations
97481view12:50, 23 May 2018Fehrhartadded annotations
97480view12:42, 23 May 2018Fehrhartadded annotations
97479view12:35, 23 May 2018Fehrhartadded annotations
97478view12:12, 23 May 2018FehrhartModified description
97477view12:11, 23 May 2018FehrhartModified description
97476view12:07, 23 May 2018Fehrhartall connections done (hopefully)
97475view12:04, 23 May 2018Fehrhartconnections
97474view12:02, 23 May 2018Fehrhartconnections...
97473view12:00, 23 May 2018Fehrhartfixed connections
97472view11:58, 23 May 2018Fehrhartfixed connections
97471view11:56, 23 May 2018Fehrhartfixed connections
97470view11:55, 23 May 2018Fehrhartfixed more connections
97469view11:53, 23 May 2018Fehrhartfixed more connections
97467view09:20, 23 May 2018Fehrhartfixed more connections
97463view08:48, 22 May 2018Fehrhartfixed connections
87959view13:12, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
83040view04:29, 18 November 2015Mkutmonfixed issue with references
83016view13:30, 17 November 2015FehrhartUpdate of outdated identifiers
79825view08:28, 17 April 2015EgonwFixed the Ensembl data source.
78569view14:50, 7 January 2015MaintBotadded missing graphIds
78210view14:44, 14 December 2014EgonwChanged schema.
78209view14:42, 14 December 2014MaintBotModified title
78095view11:38, 2 December 2014RiannefijtenNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABCB11GeneProductENSG00000073734 (Ensembl)
ABCB1GeneProductENSG00000085563 (Ensembl)
ABCB4GeneProductENSG00000005471 (Ensembl)
ABCC2GeneProductENSG00000023839 (Ensembl)
ABCC3GeneProductENSG00000108846 (Ensembl)
ABCC4GeneProductENSG00000125257 (Ensembl)
ABCC5GeneProductENSG00000114770 (Ensembl)
ABCG5GeneProductENSG00000138075 (Ensembl)
ABCG8GeneProductENSG00000143921 (Ensembl)
ABHD2GeneProductENSG00000140526 (Ensembl)
ACAA1GeneProductENSG00000060971 (Ensembl)
ACADMGeneProductENSG00000117054 (Ensembl)
ACOX1GeneProductENSG00000161533 (Ensembl)
ADH7GeneProductENSG00000196344 (Ensembl)
AGERGeneProductENSG00000204305 (Ensembl)
AHRGeneProductENSG00000106546 (Ensembl)
AHRRGeneProductENSG00000063438 (Ensembl)
AIPGeneProductENSG00000110711 (Ensembl)
AKAP13GeneProductENSG00000170776 (Ensembl)
ALAS1GeneProductENSG00000023330 (Ensembl)
ALDH3A1GeneProductENSG00000108602 (Ensembl)
ALOX5APGeneProductENSG00000132965 (Ensembl)
AMIGO2GeneProductENSG00000139211 (Ensembl)
ANGPTL4GeneProductENSG00000167772 (Ensembl)
ANKRD1GeneProductENSG00000148677 (Ensembl)
APOA1GeneProductENSG00000118137 (Ensembl)
APOA2GeneProductENSG00000158874 (Ensembl)
APOA5GeneProductENSG00000110243 (Ensembl)
APOC3GeneProductENSG00000110245 (Ensembl)
ARL5BGeneProductENSG00000165997 (Ensembl)
ARNTGeneProduct405 (Entrez Gene)
Antioxidant proteinsPathway
B3GNT5GeneProductENSG00000176597 (Ensembl)
BAATGeneProductENSG00000136881 (Ensembl)
BAX GeneProductENSG00000087088 (Ensembl)
BHLHE40GeneProductENSG00000134107 (Ensembl)
BIRC2GeneProductENSG00000110330 (Ensembl)
BIRC3GeneProductENSG00000023445 (Ensembl)
BLVRBGeneProductENSG00000090013 (Ensembl)
Bile acid detoxificationPathway
Bile acid neosynthesisPathway
Bile acid & xenobiotics transportPathway
CAP2GeneProductENSG00000112186 (Ensembl)
CBR1GeneProductENSG00000159228 (Ensembl)
CBR3GeneProductENSG00000159231 (Ensembl)
CCL20GeneProductENSG00000115009 (Ensembl)
CCL2GeneProductENSG00000108691 (Ensembl)
CCND1GeneProductENSG00000110092 (Ensembl)
CDC37GeneProductENSG00000105401 (Ensembl)
CDC42EP3GeneProductENSG00000163171 (Ensembl)
CDK1GeneProductENSG00000170312 (Ensembl)
CDK4GeneProductENSG00000135446 (Ensembl)
CDKN1BGeneProductENSG00000111276 (Ensembl)
CDKN1CGeneProductENSG00000129757 (Ensembl)
CES1GeneProductENSG00000198848 (Ensembl)
CES2GeneProductENSG00000172831 (Ensembl)
CES3GeneProductENSG00000172828 (Ensembl)
CES4AGeneProductENSG00000172824 (Ensembl)
CES5AGeneProductENSG00000159398 (Ensembl)
CPEB4GeneProductENSG00000113742 (Ensembl)
CPT1AGeneProductENSG00000110090 (Ensembl)
CPT2GeneProductENSG00000157184 (Ensembl)
CUL1GeneProductENSG00000055130 (Ensembl)
CXCR7GeneProductENSG00000144476 (Ensembl)
CYP1A1GeneProductENSG00000140465 (Ensembl)
CYP1A2GeneProductENSG00000140505 (Ensembl)
CYP1B1GeneProductENSG00000138061 (Ensembl)
CYP2A6GeneProductENSG00000255974 (Ensembl)
CYP2B6GeneProductENSG00000197408 (Ensembl)
CYP2C19GeneProductENSG00000165841 (Ensembl)
CYP2C9GeneProductENSG00000138109 (Ensembl)
CYP3A4GeneProductENSG00000160868 (Ensembl)
CYP3A5GeneProductENSG00000106258 (Ensembl)
CYP3A7GeneProductENSG00000160870 (Ensembl)
CYP4A11GeneProductENSG00000187048 (Ensembl)
CYP4F12GeneProductENSG00000186204 (Ensembl)
CYP7A1GeneProductENSG00000167910 (Ensembl)
CYP8B1GeneProductENSG00000180432 (Ensembl)
Cell proliferation and apoptosisPathway
Cell proliferation

and differentiation

Pathway
Cholesterol catabolismPathway
Co-activators
DBIGeneProductENSG00000155368 (Ensembl)
DNAJB1GeneProductENSG00000132002 (Ensembl)
DNAJC15GeneProductENSG00000120675 (Ensembl)
DNAJC7GeneProductENSG00000168259 (Ensembl)
DNERGeneProductENSG00000187957 (Ensembl)
DegradationPathway
Drug and steroid metabolismPathway
EDN2GeneProductENSG00000127129 (Ensembl)
EGFR pathwayPathway
EGFRGeneProductENSG00000146648 (Ensembl)
EGR1GeneProductENSG00000120738 (Ensembl)
EHHADHGeneProductENSG00000113790 (Ensembl)
ENC1GeneProductENSG00000171617 (Ensembl)
EP300GeneProductENSG00000100393 (Ensembl)
EPB41L4BGeneProductENSG00000095203 (Ensembl)
EPHA2GeneProductENSG00000142627 (Ensembl)
EPHA3GeneProductENSG00000044524 (Ensembl)
ESR1GeneProductENSG00000091831 (Ensembl)
ETNK2GeneProductENSG00000143845 (Ensembl)
FABP1GeneProductENSG00000163586 (Ensembl)
FASNGeneProductENSG00000169710 (Ensembl)
FGD4GeneProductENSG00000139132 (Ensembl)
FGF13GeneProductENSG00000129682 (Ensembl)
FGF19GeneProductENSG00000162344 (Ensembl)
FGFBP1GeneProductENSG00000137440 (Ensembl)
FKBP5GeneProductENSG00000096060 (Ensembl)
FOXO1GeneProductENSG00000150907 (Ensembl)
FTH1GeneProductENSG00000167996 (Ensembl)
FTLGeneProductENSG00000087086 (Ensembl)
G6PDGeneProductENSG00000160211 (Ensembl)
GADD45BGeneProductENSG00000099860 (Ensembl)
GCC1GeneProductENSG00000179562 (Ensembl)
GCLCGeneProductENSG00000001084 (Ensembl)
GCLMGeneProductENSG00000023909 (Ensembl)
GGT1GeneProductENSG00000100031 (Ensembl)
GPAMGeneProductENSG00000119927 (Ensembl)
GPR115GeneProductENSG00000153294 (Ensembl)
GPR153GeneProductENSG00000158292 (Ensembl)
GPX2GeneProductENSG00000176153 (Ensembl)
GPX3GeneProductENSG00000211445 (Ensembl)
GSRGeneProductENSG00000104687 (Ensembl)
GSTA1GeneProductENSG00000243955 (Ensembl)
GSTA2GeneProductENSG00000244067 (Ensembl)
GSTA3GeneProductENSG00000174156 (Ensembl)
GSTA4GeneProductENSG00000170899 (Ensembl)
GSTA5GeneProductENSG00000182793 (Ensembl)
GSTM1GeneProductENSG00000134184 (Ensembl)
GSTM2GeneProductENSG00000213366 (Ensembl)
GSTM3GeneProductENSG00000134202 (Ensembl)
GSTM4GeneProductENSG00000168765 (Ensembl)
GSTM5GeneProductENSG00000134201 (Ensembl)
GSTP1GeneProductENSG00000084207 (Ensembl)
GSTT1GeneProductENSG00000277656 (Ensembl)
GSTT2GeneProductENSG00000099984 (Ensembl)
Growth and apoptosisPathway
Growth factors and receptorsPathway
HBEGFGeneProductENSG00000113070 (Ensembl)
HES1GeneProductENSG00000114315 (Ensembl)
HGFGeneProductENSG00000019991 (Ensembl)
HMOX1GeneProductENSG00000100292 (Ensembl)
HSP90AA1 GeneProductENSG00000080824 (Ensembl)
HSP90AA1GeneProductENSG00000080824 (Ensembl)
HSP90AB1GeneProductENSG00000096384 (Ensembl)
HSPA1AGeneProductENSG00000204389 (Ensembl)
Hepatocyte proliferationPathwayin mice (possibly also in humans?)
IFNGGeneProductENSG00000111537 (Ensembl)
IGFBP1 GeneProductENSG00000146678 (Ensembl)
IL11GeneProductENSG00000095752 (Ensembl)
IL12AGeneProductENSG00000168811 (Ensembl)
IL12BGeneProductENSG00000113302 (Ensembl)
IL17BGeneProductENSG00000127743 (Ensembl)
IL1BGeneProductENSG00000125538 (Ensembl)
IL2 GeneProductENSG00000109471 (Ensembl)
IP6K3GeneProductENSG00000161896 (Ensembl)
IRS2GeneProductENSG00000185950 (Ensembl)
InflammationPathway
JUNBGeneProductENSG00000171223 (Ensembl)
JUNDGeneProductENSG00000130522 (Ensembl)
JUNGeneProductENSG00000177606 (Ensembl)
KAT2BGeneProductENSG00000114166 (Ensembl)
KEAP1GeneProductENSG00000079999 (Ensembl)
KLK15GeneProductENSG00000174562 (Ensembl)
KTN1GeneProductENSG00000126777 (Ensembl)
LRRC8AGeneProductENSG00000136802 (Ensembl)
Ligand
Ligand ProteinOmeprazole, TCDD, PCB
MAFFGeneProductENSG00000185022 (Ensembl)
MAFGGeneProductENSG00000197063 (Ensembl)
ME1GeneProductENSG00000065833 (Ensembl)
MFGE8GeneProductENSG00000140545 (Ensembl)
MGAMGeneProductENSG00000179087 (Ensembl)
MGST1GeneProductENSG00000008394 (Ensembl)
MGST2GeneProductENSG00000085871 (Ensembl)
MGST3GeneProductENSG00000143198 (Ensembl)
MT1IPGeneProduct644314 (Entrez Gene)
MYCGeneProductENSG00000136997 (Ensembl)
MYOFGeneProductENSG00000138119 (Ensembl)
MetabolismPathway
Multi-drug resistancePathway
NAV3GeneProductENSG00000067798 (Ensembl)
NCOA1GeneProductENSG00000084676 (Ensembl)
NCOA2GeneProductENSG00000140396 (Ensembl)
NCOA3GeneProductENSG00000124151 (Ensembl)
NCOA6GeneProductENSG00000198646 (Ensembl)
NFE2L2GeneProductENSG00000116044 (Ensembl)
NFKB2GeneProductENSG00000077150 (Ensembl)
NQO1GeneProductENSG00000181019 (Ensembl)
NR0B2GeneProductENSG00000131910 (Ensembl)
NR1H3GeneProductENSG00000025434 (Ensembl)
NR1H4GeneProductENSG00000012504 (Ensembl)
NR1I2GeneProductENSG00000144852 (Ensembl)
NR1I3GeneProductENSG00000143257 (Ensembl)
NR3C1GeneProductENSG00000113580 (Ensembl)
NRG1GeneProductENSG00000157168 (Ensembl)
NRIP1GeneProductENSG00000180530 (Ensembl)
Nuclear receptorsPathway
OtherPathway
PCK1GeneProductENSG00000124253 (Ensembl)
PDE4BGeneProductENSG00000184588 (Ensembl)
PDGFBGeneProductENSG00000100311 (Ensembl)
PDK4GeneProductENSG00000004799 (Ensembl)
PGDGeneProductENSG00000142657 (Ensembl)
PLK2GeneProductENSG00000145632 (Ensembl)
PLTPGeneProductENSG00000100979 (Ensembl)
PMP2GeneProductENSG00000147588 (Ensembl)
POLKGeneProductENSG00000122008 (Ensembl)
POU5F1GeneProductENSG00000204531 (Ensembl)
PPAR alpha ligand
PPARAGeneProductENSG00000186951 (Ensembl)
PPARDGeneProductENSG00000112033 (Ensembl)
PPARGC1AGeneProductENSG00000109819 (Ensembl)
PPP1R14CGeneProductENSG00000198729 (Ensembl)
PPP2R4GeneProductENSG00000119383 (Ensembl) plays a role in translocation of CAR
PRDX1GeneProductENSG00000117450 (Ensembl)
PRDX6GeneProductENSG00000117592 (Ensembl)
PRRG4GeneProductENSG00000135378 (Ensembl)
PSMC5GeneProductENSG00000087191 (Ensembl)
PTGES3GeneProductENSG00000110958 (Ensembl)
PTGR1GeneProductENSG00000106853 (Ensembl)
PTGS2GeneProductENSG00000073756 (Ensembl)
Phase 1

proteins

Pathway
Phase 2 metabolismPathway
Phase 2

proteins

Pathway
RGS2GeneProductENSG00000116741 (Ensembl)
RXRAGeneProductENSG00000186350 (Ensembl)
S100PGeneProductENSG00000163993 (Ensembl)
SCDGeneProductENSG00000099194 (Ensembl)
SCNN1AGeneProductENSG00000111319 (Ensembl)
SCP2GeneProductENSG00000116171 (Ensembl)
SDPRGeneProductENSG00000168497 (Ensembl)
SEC14L1GeneProductENSG00000129657 (Ensembl)
SERPINA1GeneProductENSG00000197249 (Ensembl)
SERPINB2GeneProductENSG00000197632 (Ensembl)
SERPINB9GeneProductENSG00000170542 (Ensembl)
SERTAD2GeneProductENSG00000179833 (Ensembl)
SLC10A1GeneProductENSG00000100652 (Ensembl) inhibition
SLC19A2GeneProductENSG00000117479 (Ensembl)
SLC26A2GeneProductENSG00000155850 (Ensembl)
SLC27A1GeneProductENSG00000130304 (Ensembl)
SLC27A5GeneProductENSG00000083807 (Ensembl)
SLC2A10GeneProductENSG00000197496 (Ensembl)
SLC2A11GeneProductENSG00000133460 (Ensembl)
SLC2A12GeneProductENSG00000146411 (Ensembl)
SLC2A13GeneProductENSG00000151229 (Ensembl)
SLC2A14GeneProductENSG00000173262 (Ensembl)
SLC2A1GeneProductENSG00000117394 (Ensembl)
SLC2A2GeneProductENSG00000163581 (Ensembl)
SLC2A3GeneProductENSG00000059804 (Ensembl)
SLC2A4GeneProductENSG00000181856 (Ensembl)
SLC2A5GeneProductENSG00000142583 (Ensembl)
SLC2A6GeneProductENSG00000160326 (Ensembl)
SLC2A7GeneProductENSG00000197241 (Ensembl)
SLC2A8GeneProductENSG00000136856 (Ensembl)
SLC2A9GeneProductENSG00000109667 (Ensembl)
SLC39A10GeneProductENSG00000196950 (Ensembl)
SLC39A11GeneProductENSG00000133195 (Ensembl)
SLC39A12GeneProductENSG00000148482 (Ensembl)
SLC39A13GeneProductENSG00000165915 (Ensembl)
SLC39A14GeneProductENSG00000104635 (Ensembl)
SLC39A1GeneProductENSG00000143570 (Ensembl)
SLC39A2GeneProductENSG00000165794 (Ensembl)
SLC39A3GeneProductENSG00000141873 (Ensembl)
SLC39A4GeneProductENSG00000147804 (Ensembl)
SLC39A5GeneProductENSG00000139540 (Ensembl)
SLC39A6GeneProductENSG00000141424 (Ensembl)
SLC39A7GeneProductENSG00000112473 (Ensembl)
SLC39A8GeneProductENSG00000138821 (Ensembl)
SLC39A9GeneProductENSG00000029364 (Ensembl)
SLC5A10GeneProductENSG00000154025 (Ensembl)
SLC5A11GeneProductENSG00000158865 (Ensembl)
SLC5A12GeneProductENSG00000148942 (Ensembl)
SLC5A1GeneProductENSG00000100170 (Ensembl)
SLC5A2GeneProductENSG00000140675 (Ensembl)
SLC5A3GeneProductENSG00000198743 (Ensembl)
SLC5A4GeneProductENSG00000100191 (Ensembl)
SLC5A5GeneProductENSG00000105641 (Ensembl)
SLC5A6GeneProductENSG00000138074 (Ensembl)
SLC5A7GeneProductENSG00000115665 (Ensembl)
SLC5A8GeneProductENSG00000256870 (Ensembl)
SLC5A9GeneProductENSG00000117834 (Ensembl)
SLC6A11GeneProductENSG00000132164 (Ensembl)
SLC6A13GeneProductENSG00000010379 (Ensembl)
SLC6A14GeneProductENSG00000268104 (Ensembl)
SLC6A15GeneProductENSG00000072041 (Ensembl)
SLC6A16GeneProductENSG00000063127 (Ensembl)
SLC6A17GeneProductENSG00000197106 (Ensembl)
SLC6A18GeneProductENSG00000164363 (Ensembl)
SLC6A19GeneProductENSG00000174358 (Ensembl)
SLC6A1GeneProductENSG00000157103 (Ensembl)
SLC6A20GeneProductENSG00000163817 (Ensembl)
SLC6A2GeneProductENSG00000103546 (Ensembl)
SLC6A3GeneProductENSG00000142319 (Ensembl)
SLC6A4GeneProductENSG00000108576 (Ensembl)
SLC6A5GeneProductENSG00000165970 (Ensembl)
SLC6A6GeneProductENSG00000131389 (Ensembl)
SLC6A7GeneProductENSG00000011083 (Ensembl)
SLC6A8GeneProductENSG00000130821 (Ensembl)
SLC6A9GeneProductENSG00000196517 (Ensembl)
SLC7A11GeneProductENSG00000151012 (Ensembl)
SLC7A5GeneProductENSG00000103257 (Ensembl)
SLCO1B1GeneProductENSG00000134538 (Ensembl)
SLCO2B1GeneProductENSG00000137491 (Ensembl) inhibition
SMARCA1GeneProductENSG00000102038 (Ensembl)
SMC1AGeneProductENSG00000072501 (Ensembl)
SNAI2GeneProductENSG00000019549 (Ensembl)
SOD3GeneProductENSG00000109610 (Ensembl)
SP1GeneProductENSG00000185591 (Ensembl)
SPINK13GeneProductENSG00000214510 (Ensembl)
SPRY1GeneProductENSG00000164056 (Ensembl)
SQSTM1GeneProductENSG00000161011 (Ensembl)
SRC GeneProductENSG00000197122 (Ensembl)
SRC GeneProductENSG00000197122 (Ensembl)
SRCGeneProductENSG00000197122 (Ensembl)
SREBF1GeneProductENSG00000072310 (Ensembl)
SRGNGeneProductENSG00000122862 (Ensembl)
SRPX2GeneProductENSG00000102359 (Ensembl)
SRXN1GeneProductENSG00000172070 (Ensembl)
STAT3GeneProductENSG00000168610 (Ensembl)
STOMGeneProductENSG00000148175 (Ensembl)
SULT1A1GeneProductENSG00000196502 (Ensembl) during fasting
SULT2A1GeneProductENSG00000105398 (Ensembl)
Signal transductionPathway
TGFAGeneProductENSG00000163235 (Ensembl)
TGFB1GeneProductENSG00000105329 (Ensembl)
TGFB2GeneProductENSG00000092969 (Ensembl)
TGFBR2GeneProductENSG00000163513 (Ensembl)
TGFBR3GeneProductENSG00000069702 (Ensembl)
THBDGeneProductENSG00000178726 (Ensembl)
TNF GeneProductENSG00000232810 (Ensembl)
TNFAIP3GeneProductENSG00000118503 (Ensembl)
TNS4GeneProductENSG00000131746 (Ensembl)
TSC22D3GeneProductENSG00000157514 (Ensembl)
TXNGeneProductENSG00000136810 (Ensembl)
TXNRD1GeneProductENSG00000198431 (Ensembl)
TXNRD3GeneProductENSG00000197763 (Ensembl)
Transcription factorsPathway
TransportPathway
UGT1A1GeneProductENSG00000241635 (Ensembl)
UGT1A3GeneProductENSG00000243135 (Ensembl)
UGT1A4GeneProductENSG00000244474 (Ensembl)
UGT1A6GeneProductENSG00000167165 (Ensembl)
UGT1A7GeneProductENSG00000244122 (Ensembl)
UGT1A9GeneProductENSG00000241119 (Ensembl)
UGT2B4GeneProductENSG00000156096 (Ensembl)
UGT2B7GeneProductENSG00000171234 (Ensembl)
Unknown
VDRGeneProductENSG00000111424 (Ensembl)
ZIC2GeneProductENSG00000043355 (Ensembl)
bile acid conjugationPathway
fatty acid transportPathway
lipoprotein metabolismPathway
mitochondrial beta-oxidationPathway
mitochondrial omega-oxidationPathway
p23GeneProductENSG00000110958 (Ensembl)
peroxisomal beta-oxidationPathway

Annotated Interactions

No annotated interactions
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