Major receptors targeted by epinephrine and norepinephrine (Homo sapiens)
From WikiPathways
Description
The physiologic actions of adrenergic receptors when stimulated by epinephrine/norepinephrine
Quality Tags
Ontology Terms
Bibliography
- Glen D. Lawrence; ''The Fats of Life: Essential Fatty Acids in Health and Disease''; Rutgers University Press; ISBN 978-0-8135-4677-3, 2010
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
AC | Protein | 4.6.1.1 (Enzyme Nomenclature) | "There are ten known isoforms of adenylyl cyclases in mammals" [https://en.wikipedia.org/wiki/Adenylyl_cyclase] |
ADCY10 | Protein | Q96PN6 (Uniprot-TrEMBL) | |
ADCY1 | Protein | Q08828 (Uniprot-TrEMBL) | |
ADCY2 | Protein | Q08462 (Uniprot-TrEMBL) | |
ADCY3 | Protein | O60266 (Uniprot-TrEMBL) | |
ADCY4 | Protein | Q8NFM4 (Uniprot-TrEMBL) | |
ADCY5 | Protein | O95622 (Uniprot-TrEMBL) | |
ADCY6 | Protein | O43306 (Uniprot-TrEMBL) | |
ADCY7 | Protein | P51828 (Uniprot-TrEMBL) | |
ADCY8 | Protein | P40145 (Uniprot-TrEMBL) | |
ADCY9 | Protein | O60503 (Uniprot-TrEMBL) | |
ATP | Metabolite | CHEBI:30616 (ChEBI) | |
DAG | Metabolite | Q161466 (Wikidata) | diacylglycerol |
Epinephrine | Metabolite | Q132621 (Wikidata) | AKA adrenaline |
Glycogen breakdown | Pathway | WP500 (WikiPathways) | |
Glycogen synthesis | Pathway | WP500 (WikiPathways) | |
Glycolysis | Pathway | WP534 (WikiPathways) | |
IP3 | Metabolite | inositol triphosphate | |
Neurotransmitters | Pathway | WP4220 (WikiPathways) | |
Norepinephrine | Metabolite | ||
PIP3 | Metabolite | inositol 4,5-biphosphate | |
PKA | Protein | 2.7.11.11 (Enzyme Nomenclature) | Protein Kinase A |
PKC | Protein | 2.7.11.13 (Enzyme Nomenclature) | Protein Kinase C |
Serine | Metabolite | CHEBI:17115 (ChEBI) | |
Threonine | Metabolite | CHEBI:57926 (ChEBI) | |
cAMP | Metabolite | CHEBI:58165 (ChEBI) | |
calcium | Metabolite | CHEBI:22984 (ChEBI) | |
pyro- phosphate | Metabolite | CHEBI:33019 (ChEBI) | |
α1A receptor | Protein | P3548 (Uniprot-TrEMBL) | |
α1B receptor | Protein | P3568 (Uniprot-TrEMBL) | |
α1D receptor | Protein | P25100 (Uniprot-TrEMBL) | |
α2A receptor | Protein | P08913 (Uniprot-TrEMBL) | |
α2B receptor | Protein | P18089 (Uniprot-TrEMBL) | |
α2C receptor | Protein | P18825 (Uniprot-TrEMBL) | |
β1 receptor | Protein | P08588 (Uniprot-TrEMBL) | G protein–coupled receptor (GPCR) |
β2 receptor | Protein | P07550 (Uniprot-TrEMBL) | G protein–coupled receptor (GPCR) |
Annotated Interactions
Source | Target | Type | Database reference | Comment |
---|---|---|---|---|
ATP | cAMP | mim-conversion | 15390 (Rhea) | |
pyro- phosphate | mim-conversion | 15390 (Rhea) |