Ketogenesis and ketolysis (Homo sapiens)

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1MRCCapillaryOXCT1Mitochondrial LC-Fatty Acid Beta-OxidationATPCPT1CBDH1BHIBBHIBBHIBacetoneacetoneAcetoacetateAcetoacetateAcetoacetateAcetyl-CoAMitochondrial LC-Fatty Acid Beta-OxidationBHIBglucoseglucoseglucoseTCA (Krebs)cycleAcetoacetyl-CoASLC16A1UCP2pyruvatepyruvateAcetyl-CoASLC2A1NeuronHepatocyteBlood Brain BarrierCO2OxaloacetateGluconeogenesisTCA (Krebs)cycleGlialGycolysisKetogenesisACAT2acetone


Description

Ketogenesis and ketolysis

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Quality Tags

Ontology Terms

 

Bibliography

  1. Newman JC, Verdin E; ''β-Hydroxybutyrate: A Signaling Metabolite.''; Annu Rev Nutr, 2017 PubMed Europe PMC Scholia
  2. Noebels JL, Avoli M, Rogawski MA, Olsen R, Delgado-Escueta A; ''Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition.''; https://www.ncbi.nlm.nih.gov/books/NBK98219/figure/masino.f1/; National Center for Biotechnology Information (US), 2012
  3. Olson AL, Pessin JE; ''Structure, function, and regulation of the mammalian facilitative glucose transporter gene family.''; Annu Rev Nutr, 1996 PubMed Europe PMC Scholia
  4. Sharpe AJ, McKenzie M; ''Mitochondrial Fatty Acid Oxidation Disorders Associated with Short-Chain Enoyl-CoA Hydratase (ECHS1) Deficiency.''; Cells, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
122056view13:30, 9 March 2022SamDrabbePathway annotation ketogenesis adjusted
119118view08:48, 18 June 2021FinterlyAdded ISBN for book citation
117768view13:29, 22 May 2021EweitzModified title
108452view13:56, 20 December 2019DeSlOntology Term : 'glial cell' added !
108451view13:55, 20 December 2019DeSlOntology Term : 'PW:0000002' removed !
108450view13:55, 20 December 2019DeSlOntology Term : 'ketone bodies degradation pathway' added !
108449view13:54, 20 December 2019DeSlOntology Term : 'ketone bodies metabolic pathway' added !
108448view13:54, 20 December 2019DeSlModified description
108447view13:49, 20 December 2019DeSlUpdated right side of PW.
108446view13:25, 20 December 2019DeSlUpdated middle part
108445view13:03, 20 December 2019DeSlStarted updating lefthand side of PW
107929view21:23, 11 November 2019Khanspersconnected interaction
107914view10:03, 10 November 2019EgonwMissed one sec ChEBI ID :(
107911view09:14, 10 November 2019EgonwBetter representation for mediated translocations.
107910view09:07, 10 November 2019EgonwFixed two interactions, which are not conversions.
107909view09:03, 10 November 2019EgonwReplaced secondary ChEBI identifiers with a primary identifiers.
107901view19:32, 9 November 2019RGrosmanCOntology Term : 'neuron' added !
107900view19:32, 9 November 2019RGrosmanCOntology Term : 'hepatocyte' added !
107899view19:31, 9 November 2019RGrosmanCOntology Term : 'classic metabolic pathway' added !
107898view19:30, 9 November 2019RGrosmanCNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACAT2GeneProductENSG00000120437 (Ensembl)
ATPMetaboliteCHEBI:15422 (ChEBI)
AcetoacetateMetaboliteCHEBI:15344 (ChEBI)
Acetoacetyl-CoAMetaboliteCHEBI:15345 (ChEBI)
Acetyl-CoAMetaboliteCHEBI:15351 (ChEBI)
Acetyl-CoAMetaboliteCHEBI:2408 (ChEBI)
BDH1GeneProductENSG00000161267 (Ensembl)
BHIBMetaboliteCHEBI:17066 (ChEBI)
CO2MetaboliteCHEBI:16526 (ChEBI)
CPT1CGeneProductENSG00000169169 (Ensembl)
GluconeogenesisPathwayWP4740 (WikiPathways)
GycolysisPathwayWP4277 (WikiPathways)
KetogenesisPathwayWP4741 (WikiPathways)
Mitochondrial LC-Fatty Acid Beta-OxidationPathwayWP368 (WikiPathways)
OXCT1GeneProductENSG00000083720 (Ensembl)
OxaloacetateMetaboliteCHEBI:30744 (ChEBI)
SLC16A1GeneProductENSG00000155380 (Ensembl)
SLC2A1GeneProductENSG00000117394 (Ensembl)
TCA (Krebs)cyclePathwayWP78 (WikiPathways)
UCP2GeneProductENSG00000175567 (Ensembl)
acetoneMetaboliteCHEBI:15347 (ChEBI)
glucoseMetaboliteCHEBI:17234 (ChEBI)
pyruvateMetaboliteCHEBI:15361 (ChEBI)

Annotated Interactions

No annotated interactions

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