Translation factors (Caenorhabditis elegans)

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143S Pre-initiation ComplexRecruitment of 60S subunitPre-initiation ComplexAUG60S SubunitBinds aminoacyl-tRNAand first peptide bondTranslocationm7G40S SubunitTerminationmRNAAAAAAAAAAAAAAAARecruitment of 43SCap Binding ComplexGuanine Nucleotide ExchangescanningElongationInitiationinf-1EIF4G1EIF4Beif-3.BEIF4EBP3pek-1eif-3.DEIF4EBP1EIF4EBP2eft-3ppp-1EIF4G3F11A3.2KIAA0664F17C11.9eif-3.Ieif-6efk-1Y54F10BM.2GSPT2H06H21.3eft-4EIF2AK1pab-1eif-3.FEIF1AYY41E3.10PAIP1C37C3.2eif-3.HT05H4.6Y37E3.10EIF2B5EIF3S1EIF2AK2EIF2B2EIF4A1ZK1098.4F54H12.6SUI1WBSCR1EIF3S8EIF2S3K04G2.1eif-3.Eife-3eif-3.Giff-1SUI1egl-45eft-2


Description

Eukaryotic protein synthesis (aka translation) can be studied in C. elegans, since this species shares many more features to hihgher eukaryptes (as compared to yeast).

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Quality Tags

Ontology Terms

 

Bibliography

  1. Rhoads, R. E. et al.; ''Mechanism and regulation of translation in C. elegans''; WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.63.1, 2006 DOI Scholia

History

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CompareRevisionActionTimeUserComment
125264view12:53, 31 January 2023LarsgwAdd DOI to reference
118540view11:20, 28 May 2021DeSlfixed 2 typos in description
118539view11:19, 28 May 2021DeSlOntology Term : 'regulatory pathway' added !
118538view11:18, 28 May 2021DeSlRemoved comment under GenMAPP notes
118537view11:18, 28 May 2021DeSlModified description
118536view11:17, 28 May 2021DeSlAdded description
118535view11:13, 28 May 2021DeSlAdded lit. ref
118406view14:14, 27 May 2021Fehrhartfixed unconnected line
118208view11:43, 26 May 2021EweitzModified title
97043view15:04, 26 April 2018TimverbruggenConnected lines
78050view12:21, 23 November 2014EgonwRemoved database source when no identifier was given.
68497view21:08, 5 July 2013MaintBotUpdated to 2013 gpml schema
67707view11:52, 26 June 2013DdiglesOntology Term : 'translation pathway' added !
40650view19:58, 1 March 2011MaintBotRemoved redundant pathway information and comments
20915view11:30, 14 November 2008MaintBot[[Pathway:Caenorhabditis elegans:Translation Factors]] moved to [[Pathway:WP110]]: Moved to stable identifier
8504view14:01, 7 January 2008MaintBotAdded to category $category
8502view14:01, 7 January 2008KdahlquistUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
C37C3.2GeneProduct179165 (Entrez Gene)
EIF1AYGeneProduct
EIF2AK1GeneProduct
EIF2AK2GeneProductnow E2K2_HUMAN
EIF2B2GeneProduct
EIF2B5GeneProduct
EIF2S3GeneProduct
EIF3S1GeneProduct
EIF3S8GeneProduct
EIF4A1GeneProduct
EIF4BGeneProduct
EIF4EBP1GeneProduct
EIF4EBP2GeneProduct
EIF4EBP3GeneProduct
EIF4G1GeneProductTrEMBL accession number O43177 refers to same protein.
EIF4G3GeneProduct
F11A3.2GeneProduct179331 (Entrez Gene)
F17C11.9GeneProduct179522 (Entrez Gene)
F54H12.6GeneProduct176120 (Entrez Gene)
GSPT2GeneProduct
H06H21.3GeneProduct177254 (Entrez Gene)
K04G2.1GeneProduct172584 (Entrez Gene)
KIAA0664GeneProduct
PAIP1GeneProduct
SUI1GeneProduct
T05H4.6GeneProduct179028 (Entrez Gene)
WBSCR1GeneProduct
Y37E3.10GeneProduct171769 (Entrez Gene)
Y41E3.10GeneProduct178419 (Entrez Gene)
Y54F10BM.2GeneProduct175353 (Entrez Gene)
ZK1098.4GeneProduct176348 (Entrez Gene)
efk-1GeneProduct175871 (Entrez Gene)
eft-2GeneProduct172743 (Entrez Gene)
eft-3GeneProduct175975 (Entrez Gene)
eft-4GeneProduct181044 (Entrez Gene)
egl-45GeneProduct176094 (Entrez Gene)
eif-3.BGeneProduct175138 (Entrez Gene)
eif-3.DGeneProduct176268 (Entrez Gene)
eif-3.EGeneProduct172959 (Entrez Gene)
eif-3.FGeneProduct174478 (Entrez Gene)
eif-3.GGeneProduct174346 (Entrez Gene)
eif-3.HGeneProduct172044 (Entrez Gene)
eif-3.IGeneProduct171809 (Entrez Gene)
eif-6GeneProduct173169 (Entrez Gene)
ife-3GeneProduct178536 (Entrez Gene)
iff-1GeneProduct176373 (Entrez Gene)
inf-1GeneProduct175966 (Entrez Gene)
pab-1GeneProduct172920 (Entrez Gene)
pek-1GeneProduct181334 (Entrez Gene)
ppp-1GeneProduct174138 (Entrez Gene)

Annotated Interactions

No annotated interactions

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