Monoamine GPCRs (Homo sapiens)
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Description
G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia
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External references
DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| ADRA1A | GeneProduct | 148 (Entrez Gene)  | |
| ADRA1B | GeneProduct | 147 (Entrez Gene) | |
| ADRA1D | GeneProduct | 146 (Entrez Gene) | |
| ADRA2A | GeneProduct | 150 (Entrez Gene) | |
| ADRA2B | GeneProduct | 151 (Entrez Gene) | |
| ADRA2C | GeneProduct | 152 (Entrez Gene) | |
| ADRB1 | GeneProduct | 153 (Entrez Gene) | |
| ADRB2 | GeneProduct | 154 (Entrez Gene) | |
| ADRB3 | GeneProduct | 155 (Entrez Gene) | |
| Acetylcholine | Metabolite | HMDB0000895 (HMDB) | |
| CHRM1 | GeneProduct | 1128 (Entrez Gene) | |
| CHRM2 | GeneProduct | 1129 (Entrez Gene) | |
| CHRM3 | GeneProduct | 1131 (Entrez Gene) | |
| CHRM4 | GeneProduct | 1132 (Entrez Gene) | |
| CHRM5 | GeneProduct | 1133 (Entrez Gene) | |
| DRD1 | GeneProduct | 1812 (Entrez Gene) | |
| DRD2 | GeneProduct | 1813 (Entrez Gene) | |
| DRD3 | GeneProduct | 1814 (Entrez Gene) | |
| DRD4 | GeneProduct | 1815 (Entrez Gene) | |
| DRD5 | GeneProduct | 1816 (Entrez Gene) | |
| Dopamine | Metabolite | 62-31-7 (CAS) | |
| Epinephrine | Metabolite | HMDB0000068 (HMDB) | |
| Gi/Go pathway | Pathway | WP35 (WikiPathways) | |
| Gq/G11 pathway | Pathway | WP35 (WikiPathways) | |
| Gs pathway | Pathway | WP35 (WikiPathways) | |
| HRH1 | GeneProduct | 3269 (Entrez Gene) | |
| HRH2 | GeneProduct | 3274 (Entrez Gene) | |
| HTR1A | GeneProduct | 3350 (Entrez Gene) | |
| HTR1B | GeneProduct | 3351 (Entrez Gene) | |
| HTR1D | GeneProduct | 3352 (Entrez Gene) | |
| HTR1E | GeneProduct | 3354 (Entrez Gene) | |
| HTR1F | GeneProduct | 3355 (Entrez Gene) | |
| HTR2A | GeneProduct | 3356 (Entrez Gene) | |
| HTR2B | GeneProduct | 3357 (Entrez Gene) | |
| HTR2C | GeneProduct | 3358 (Entrez Gene) | |
| HTR4 | GeneProduct | 3360 (Entrez Gene) | |
| HTR5A | GeneProduct | 3361 (Entrez Gene) | |
| HTR5B | GeneProduct | 645694 (Entrez Gene) | |
| HTR6 | GeneProduct | 3362 (Entrez Gene) | |
| HTR7 | GeneProduct | 3363 (Entrez Gene) | |
| Histamine | Metabolite | 51-45-6 (CAS) | |
| Muscarine | Metabolite | CHEBI:7034 (ChEBI) | |
| Norepinephrine | Metabolite | HMDB0000216 (HMDB) | |
| Serotonin | Metabolite | 50-67-9 (CAS) |
Annotated Interactions
No annotated interactions
