T cell receptor signaling pathway (Danio rerio)

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DesumoylationSumoylationMTGolgi apparatusUbiquitinationReceptorAutophosphorylationDeubiquitinationAccession Number: NetPath_11ERPalmitoylationDExtracellularAcetylationGlycosylationMitochondrionProteins in a complex interactionCY->NUCY->NUReaction through unknown mechanisms/moleculesEndosomeNUPlasma membraneCYEnzyme complexDCY->PMPhosphorylationProteolytic cleavage(Protein-protein interaction)RecruitmentDeacetylationGene SymbolNU->CYInhibitionEndoplasmic reticulumNucleusECMethylationLigandDephosphorylationAntigenCytoplasmPMENControlMolecular associationTranslocationActivationMolecule in the pathwayGODemethylationLCKYWHAQgrb2VAV2tuba8l2CD3EPRKCQCD3ECD3Zjunripk2si:dkey-78k11.1ctnnb1ptprjacblbzgc:172250SHBPPP3CBLOC564517zgc:153534STAT5AcrkENAHCH211-67F24.8cd2aplPTPRHoxsr1amapk1KHDRBS1NFAM1wu:fb79a07mapk7STAT5BSTAT5Azgc:112450ptk2.1LNKdnm2lzgc:110844pak1zgc:101809cishCD3GNCK1ptk2bbsla1LOC564899stat1aPTPRCmap2k1LOC100000665CH211-127H20.2creb1CD8Acrebbpbzgc:55557wasbNEDD9brafdlg1plcg1LOC100000720CD3DTRA@TXKFCRL3cebpbARHGEF7pxnNCK1JAK3cdc42lLOC798084ptpn6SH2D2Aarhgdigzgc:92124zgc:110383cblCD2PTPN3CD4zgc:101809LOC558288pik3r2LOC100003365UNC119LIME1sh2d3casrcsykSIT1MAP4K1HDAC7ALOC792354DTX1tubb5LOC557072zgc:63721DOCK2CD3ZPRKD2MUC1SOS1crklLATLAX1LOC796938GRAPptpn11TRB@TRAT1mapk3DKEY-234H16.4LOC557176zgc:158223si:dkey-24l11.5zgc:162320LOC793398LOC571865junRASGRP2nclPTPN12WASF2rap1aHDAC7ALOC796938STAT5Brac2CD5foszgc:171590LOC563639rasa1fynbevlbLIME1skap2LOC100151491zgc:112091VAV1itkLOC100149388wu:fk86g11


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 60% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
116910view11:48, 15 May 2021EweitzModified title
87698view08:59, 25 July 2016MirellaKalafatiOntology Term : 'signaling pathway' added !
87697view08:59, 25 July 2016MirellaKalafatiOntology Term : 'T cell' added !
68678view05:36, 6 July 2013MaintBotUpdated to 2013 gpml schema
40851view22:19, 1 March 2011MaintBotRemoved redundant pathway information and comments
34233view21:38, 9 December 2009MaintBotAutomatic update of empty xrefs
31362view20:34, 13 August 2009MaintBotFixed text labels
31055view01:23, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGEF7GeneProduct
CD2GeneProduct
CD3DGeneProduct
CD3EGeneProduct
CD3GGeneProduct
CD3ZGeneProduct
CD4GeneProduct
CD5GeneProduct
CD8AGeneProduct
CH211-127H20.2GeneProduct558635 (Entrez Gene)
CH211-67F24.8GeneProduct561670 (Entrez Gene)
DKEY-234H16.4GeneProduct793882 (Entrez Gene)
DOCK2GeneProduct
DTX1GeneProduct
ENAHGeneProduct
FCRL3GeneProduct
GRAPGeneProduct
HDAC7AGeneProduct
JAK3GeneProduct
KHDRBS1GeneProduct
LATGeneProduct
LAX1GeneProduct
LCKGeneProduct
LIME1GeneProduct
LNKGeneProduct
LOC100000665GeneProduct100000665 (Entrez Gene)
LOC100000720GeneProduct100000720 (Entrez Gene)
LOC100003365GeneProduct100003365 (Entrez Gene)
LOC100149388GeneProduct100149388 (Entrez Gene)
LOC100151491GeneProduct100151491 (Entrez Gene)
LOC557072GeneProduct557072 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC558288GeneProduct558288 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC564517GeneProduct564517 (Entrez Gene)
LOC564899GeneProduct564899 (Entrez Gene)
LOC571865GeneProduct571865 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
LOC793398GeneProduct793398 (Entrez Gene)
LOC796938GeneProduct796938 (Entrez Gene)
LOC798084GeneProduct798084 (Entrez Gene)
MAP4K1GeneProduct
MUC1GeneProduct
NCK1GeneProduct
NEDD9GeneProduct
NFAM1GeneProduct
PPP3CBGeneProduct
PRKCQGeneProduct
PRKD2GeneProduct
PTPN12GeneProduct
PTPN3GeneProduct
PTPRCGeneProduct
PTPRHGeneProduct
RASGRP2GeneProduct
SH2D2AGeneProduct
SHBGeneProduct
SIT1GeneProduct
SOS1GeneProduct
STAT5AGeneProduct
STAT5BGeneProduct
TRA@GeneProduct
TRAT1GeneProduct
TRB@GeneProduct
TXKGeneProduct
UNC119GeneProduct
VAV1GeneProduct
VAV2GeneProduct
WASF2GeneProduct
YWHAQGeneProduct
arhgdigGeneProduct394132 (Entrez Gene)
brafGeneProduct403065 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
cblbGeneProduct556277 (Entrez Gene)
cd2aplGeneProduct494040 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cebpbGeneProduct140814 (Entrez Gene)
cishGeneProduct767678 (Entrez Gene)
creb1GeneProduct573207 (Entrez Gene)
crebbpbGeneProduct503776 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
crklGeneProduct556443 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
dlg1GeneProduct114446 (Entrez Gene)
dnm2lGeneProduct406525 (Entrez Gene)
evlbGeneProduct402929 (Entrez Gene)
fosGeneProduct394198 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
itkGeneProduct798906 (Entrez Gene)
junGeneProduct335916 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
mapk7GeneProduct541323 (Entrez Gene)
nclGeneProduct767714 (Entrez Gene)
oxsr1aGeneProduct568602 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
plcg1GeneProduct373867 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
ptk2bbGeneProduct245950 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
ptprjaGeneProduct559679 (Entrez Gene)
pxnGeneProduct399546 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
rap1aGeneProduct415242 (Entrez Gene)
rasa1GeneProduct100002155 (Entrez Gene)
ripk2GeneProduct373874 (Entrez Gene)
sh2d3caGeneProduct558860 (Entrez Gene)
si:dkey-24l11.5GeneProduct571331 (Entrez Gene)
si:dkey-78k11.1GeneProduct565606 (Entrez Gene)
skap2GeneProduct368564 (Entrez Gene)
sla1GeneProduct571922 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
sykGeneProduct405769 (Entrez Gene)
tuba8l2GeneProduct393664 (Entrez Gene)
tubb5GeneProduct386701 (Entrez Gene)
wasbGeneProduct335158 (Entrez Gene)
wu:fb79a07GeneProduct571383 (Entrez Gene)
wu:fk86g11GeneProduct559145 (Entrez Gene)
zgc:101809GeneProduct336073 (Entrez Gene)
zgc:110383GeneProduct553615 (Entrez Gene)
zgc:110844GeneProduct541489 (Entrez Gene)
zgc:112091GeneProduct550452 (Entrez Gene)
zgc:112450GeneProduct553729 (Entrez Gene)
zgc:153534GeneProduct767738 (Entrez Gene)
zgc:158223GeneProduct563784 (Entrez Gene)
zgc:162320GeneProduct555805 (Entrez Gene)
zgc:171590GeneProduct568515 (Entrez Gene)
zgc:172250GeneProduct100002225 (Entrez Gene)
zgc:55557GeneProduct394088 (Entrez Gene)
zgc:63721GeneProduct394015 (Entrez Gene)
zgc:92124GeneProduct447804 (Entrez Gene)

Annotated Interactions

No annotated interactions
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