Statin pathway (Mus musculus)
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Revision as of 23:12, 8 December 2009 by
Khanspers
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Cholesterol Ester
IDL
Phospholipid
Liver cell
HDL
Free FA
Cell Membrane
Statin
VLDL
LDL
Tissues
Plasma
Triglycerides
Lipc
Cholesterol
Apoc2
Acetyl-CoA
Scarb1
Cholesterol
Soat1
Lcat
Mttp
Cholic acid
Cetp
Hmgcr
Lrp1
Apoa4
Pltp
Lpl
Dgat1
Apoa1
Apoc1
Ldlr
Apoc3
Apoe
Cyp7a1
Abca1
Description
No description
Comments
GenMAPP notes
http://www.pharmgkb.org/search/pathway/statin.jsp
GenMAPP remarks
Adapted from PharmGKB (right click for info)
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Chen H, Ikeda U, Shimpo M, Shimada K; ''Direct effects of statins on cells primarily involved in atherosclerosis.''; Hypertens Res, 2000
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
134146
view
19:55, 5 July 2024
Eweitz
Economize layout
134145
view
19:44, 5 July 2024
Eweitz
Economize layout
134144
view
19:32, 5 July 2024
Eweitz
Economize layout
134140
view
12:40, 3 July 2024
Eweitz
Standardize font size
134139
view
12:39, 3 July 2024
Eweitz
Ease nomenclature, standardize case
127970
view
15:30, 20 January 2024
Eweitz
Increase node font size, standardize case
127969
view
15:25, 20 January 2024
Eweitz
Ontology Term : 'hepatocyte' added !
117947
view
10:46, 23 May 2021
Eweitz
Modified title
107192
view
14:28, 17 September 2019
MaintBot
ChEBI identifier normalization
106833
view
13:31, 17 September 2019
MaintBot
HMDB identifier normalization
103264
view
07:46, 20 February 2019
Egonw
More specific ChEBI identifier.
102612
view
19:50, 11 January 2019
Khanspers
Ontology Term : 'cardiovascular system disease' added !
102611
view
19:50, 11 January 2019
Khanspers
Ontology Term : 'hypercholesterolemia pathway' added !
102294
view
19:17, 17 December 2018
Khanspers
Modified description
102291
view
19:14, 17 December 2018
Khanspers
Modified description
73346
view
19:53, 22 January 2014
Egonw
Added ChEBI identifiers to three metabolite classes.
69109
view
18:13, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67656
view
11:45, 26 June 2013
Ddigles
Ontology Term : 'statin drug pathway' added !
53530
view
19:14, 8 November 2012
Egonw
Updated the CHEBI id format (see http://www.pathvisio.org/ticket/1439)
53452
view
17:29, 7 November 2012
Andra
Added entrez gene identifier of Cetp after RDF tidy
50199
view
14:21, 9 August 2012
Mkutmon
added new shape forms, added xref for statin and cholesterol ester
41296
view
00:23, 2 March 2011
MaintBot
Removed redundant pathway information and comments
38714
view
19:31, 23 September 2010
AlexanderPico
35542
view
14:19, 12 February 2010
Thomas
removed genmapp remark
35540
view
14:18, 12 February 2010
Thomas
Modified description
35537
view
14:16, 12 February 2010
Thomas
added literature, fixed title
33728
view
23:21, 8 December 2009
Khanspers
Added connectors and metabolites
33727
view
23:12, 8 December 2009
Khanspers
Periodical save, work in progress
29016
view
05:30, 27 March 2009
AlexanderPico
Reverted to version '04:29, 14 November 2008' by
AlexanderPico
29015
view
05:30, 27 March 2009
AlexanderPico
Reverted to version '06:05, 14 November 2008' by
AlexanderPico
22540
view
13:05, 14 November 2008
TestUser
Soap test - 1226667890445
22538
view
13:05, 14 November 2008
TestUser
Soap test - 1226667859184
20671
view
11:29, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Statin Pathway PharmGKB]] moved to [[Pathway:WP1]]: Moved to stable identifier
11887
view
18:21, 8 May 2008
Khanspers
Changed contact info
8404
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Statin Pathway PharmGKB]] moved to [[Pathway:Mus musculus:Statin Pathway PharmGKB]]: Renaming species
7819
view
16:20, 18 December 2007
MaintBot
fixed category names
7396
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
19544
view
22:19, 22 May 2007
BruceConklin
gpml file for [[Mouse:Statin_Pathway_PharmGKB]]
6496
view
22:19, 22 May 2007
Nsalomonis
gpml file for [[Mouse:Statin_Pathway_PharmGKB]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Abca1
GeneProduct
11303 (Entrez Gene)
Acetyl-CoA
Metabolite
HMDB01206 (HMDB)
Apoa1
GeneProduct
11806 (Entrez Gene)
Apoa4
GeneProduct
11808 (Entrez Gene)
Apoc1
GeneProduct
11812 (Entrez Gene)
Apoc2
GeneProduct
11813 (Entrez Gene)
Apoc3
GeneProduct
11814 (Entrez Gene)
Apoe
GeneProduct
11816 (Entrez Gene)
Cetp
GeneProduct
Cetp (Entrez Gene)
Cholesterol
Metabolite
HMDB00067 (HMDB)
Cholic acid
Metabolite
HMDB00619 (HMDB)
Cyp7a1
GeneProduct
13122 (Entrez Gene)
Dgat1
GeneProduct
13350 (Entrez Gene)
Hmgcr
GeneProduct
15357 (Entrez Gene)
Lcat
GeneProduct
16816 (Entrez Gene)
Ldlr
GeneProduct
16835 (Entrez Gene)
Lipc
GeneProduct
15450 (Entrez Gene)
Lpl
GeneProduct
16956 (Entrez Gene)
Lrp1
GeneProduct
16971 (Entrez Gene)
Mttp
GeneProduct
17777 (Entrez Gene)
Pltp
GeneProduct
18830 (Entrez Gene)
Scarb1
GeneProduct
20778 (Entrez Gene)
Soat1
GeneProduct
20652 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Discussion
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Annotated Interactions
No annotated interactions