References: Bard, M., Bruner, D. A., Pierson, C. A., Lees, N. D., Biermann, B., Frye, L., Koegel, C., and Barbuch, R. (1996). Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase. Proc Natl Acad Sci U S A 93, 186-190.
Gaylor, J. L. (2002). Membrane-bound enzymes of cholesterol synthesis from lanosterol. Biochem Biophys Res Commun 292, 1139-1146.
Li, L., and Kaplan, J. (1996). Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue. J Biol Chem 271, 16927-16933.
Liu, X. Y., Dangel, A. W., Kelley, R. I., Zhao, W., Denny, P., Botcherby, M., Cattanach, B., Peters, J., Hunsicker, P. R., Mallon, A. M., et al. (1999). The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase. Nat Genet 22, 182-187.
Ohashi, M., Mizushima, N., Kabeya, Y., and Yoshimori, T. (2003). Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets. J Biol Chem 278, 36819-36829.
Sagami, H., Korenaga, T., and Ogura, K. (1993). Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate. J Biochem (Tokyo) 114, 118-121.
Yoshida, Y., Noshiro, M., Aoyama, Y., Kawamoto, T., Horiuchi, T., and Gotoh, O. (1997). Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: II. Evolutionary analysis of protein and gene structures. J Biochem (Tokyo) 122, 1122-1128.
GenMAPP remarks
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HomologyConvert
This pathway was inferred from Homo sapiens pathway WP197(r21093) with a 88% conversion rate.
Noshiro M, Aoyama Y, Kawamoto T, Gotoh O, Horiuchi T, Yoshida Y; ''Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: I. Structural analyses of the gene and multiple sizes of mRNA.''; J Biochem, 1997 PubMedEurope PMCScholia
Bard M, Bruner DA, Pierson CA, Lees ND, Biermann B, Frye L, Koegel C, Barbuch R; ''Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase.''; Proc Natl Acad Sci U S A, 1996 PubMedEurope PMCScholia
Li L, Kaplan J; ''Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.''; J Biol Chem, 1996 PubMedEurope PMCScholia
Ohashi M, Mizushima N, Kabeya Y, Yoshimori T; ''Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets.''; J Biol Chem, 2003 PubMedEurope PMCScholia
Liu XY, Dangel AW, Kelley RI, Zhao W, Denny P, Botcherby M, Cattanach B, Peters J, Hunsicker PR, Mallon AM, Strivens MA, Bate R, Miller W, Rhodes M, Brown SD, Herman GE; ''The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase.''; Nat Genet, 1999 PubMedEurope PMCScholia
Sagami H, Korenaga T, Ogura K; ''Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate.''; J Biochem, 1993 PubMedEurope PMCScholia
Gaylor JL; ''Membrane-bound enzymes of cholesterol synthesis from lanosterol.''; Biochem Biophys Res Commun, 2002 PubMedEurope PMCScholia
Gaylor, J. L. (2002). Membrane-bound enzymes of cholesterol synthesis from lanosterol. Biochem Biophys Res Commun 292, 1139-1146.
Li, L., and Kaplan, J. (1996). Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue. J Biol Chem 271, 16927-16933.
Liu, X. Y., Dangel, A. W., Kelley, R. I., Zhao, W., Denny, P., Botcherby, M., Cattanach, B., Peters, J., Hunsicker, P. R., Mallon, A. M., et al. (1999). The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase. Nat Genet 22, 182-187.
Ohashi, M., Mizushima, N., Kabeya, Y., and Yoshimori, T. (2003). Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets. J Biol Chem 278, 36819-36829.
Sagami, H., Korenaga, T., and Ogura, K. (1993). Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate. J Biochem (Tokyo) 114, 118-121.
Yoshida, Y., Noshiro, M., Aoyama, Y., Kawamoto, T., Horiuchi, T., and Gotoh, O. (1997). Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: II. Evolutionary analysis of protein and gene structures. J Biochem (Tokyo) 122, 1122-1128.
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