Proteasome degradation (Bos taurus)

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Review changes for Approved Revision 117056 of this pathway was approved for data analysis by Martina Kutmon.

Annotate nodes Comment: 6 out of 67 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Homology Converted Comment: Inferred from another species Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Lasker K, Förster F, Bohn S, Walzthoeni T, Villa E, Unverdorben P, Beck F, Aebersold R, Sali A, Baumeister W; ''Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach.''; Proc Natl Acad Sci U S A, 2012 PubMed Europe PMC Scholia
2. Hershko A, Ciechanover A, Varshavsky A; ''Basic Medical Research Award. The ubiquitin system.''; Nat Med, 2000 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
ATP	Metabolite
H2AFX	GeneProduct	531733 (Entrez Gene)
H2AFZ	GeneProduct	287016 (Entrez Gene)
HIST1H2AB	GeneProduct
HLA-A	GeneProduct	782684 (Entrez Gene)
HLA-B	GeneProduct
HLA-C	GeneProduct
HLA-E	GeneProduct
HLA-F	GeneProduct
HLA-G	GeneProduct
HLA-H	GeneProduct
HLA-J	GeneProduct
IFNG	GeneProduct	281237 (Entrez Gene)
NEDD4	GeneProduct	507781 (Entrez Gene)
PSMA1	GeneProduct	515503 (Entrez Gene)
PSMA2	GeneProduct	539141 (Entrez Gene)
PSMA3	GeneProduct	505176 (Entrez Gene)
PSMA4	GeneProduct	510423 (Entrez Gene)
PSMA5	GeneProduct	510155 (Entrez Gene)
PSMA6	GeneProduct	507213 (Entrez Gene)
PSMA7	GeneProduct	505050 (Entrez Gene)
PSMB10	GeneProduct	282328 (Entrez Gene)
PSMB1	GeneProduct	514237 (Entrez Gene)
PSMB2	GeneProduct	516919 (Entrez Gene)
PSMB3	GeneProduct	533874 (Entrez Gene)
PSMB4	GeneProduct	506203 (Entrez Gene)
PSMB5	GeneProduct	534640 (Entrez Gene)
PSMB6	GeneProduct	510069 (Entrez Gene)	U13393
PSMB7	GeneProduct	511207 (Entrez Gene)
PSMB8	GeneProduct	282013 (Entrez Gene)
PSMB9	GeneProduct	510593 (Entrez Gene)
PSMC1	GeneProduct	506238 (Entrez Gene)
PSMC2	GeneProduct	530186 (Entrez Gene)
PSMC3	GeneProduct	508448 (Entrez Gene)
PSMC4	GeneProduct	510029 (Entrez Gene)	PRS6 HUMAN
PSMC5	GeneProduct	282015 (Entrez Gene)	PRS6 HUMAN
PSMC6	GeneProduct	518637 (Entrez Gene)
PSMD10	GeneProduct	535414 (Entrez Gene)
PSMD11	GeneProduct	513461 (Entrez Gene)
PSMD12	GeneProduct	538204 (Entrez Gene)
PSMD13	GeneProduct	513525 (Entrez Gene)
PSMD1	GeneProduct	511803 (Entrez Gene)
PSMD2	GeneProduct	539784 (Entrez Gene)
PSMD3	GeneProduct	504937 (Entrez Gene)
PSMD4	GeneProduct	282016 (Entrez Gene)
PSMD5	GeneProduct	515021 (Entrez Gene)
PSMD6	GeneProduct	538625 (Entrez Gene)
PSMD7	GeneProduct	512456 (Entrez Gene)
PSMD8	GeneProduct	785653 (Entrez Gene)
PSMD9	GeneProduct	513315 (Entrez Gene)
PSME1	GeneProduct	510041 (Entrez Gene)
PSME2	GeneProduct	509857 (Entrez Gene)
PSME3	GeneProduct
RPN1	GeneProduct	507939 (Entrez Gene)
RPN2	GeneProduct	534231 (Entrez Gene)
UBA1	GeneProduct	282869 (Entrez Gene)
UBA7	GeneProduct	497204 (Entrez Gene)
UBB	GeneProduct
UBC	GeneProduct	444874 (Entrez Gene)
UBE2B	GeneProduct	512207 (Entrez Gene)
UBE2D1	GeneProduct	535287 (Entrez Gene)
UBE2D2	GeneProduct	541003 (Entrez Gene)
UBE2D3	GeneProduct
UCHL1_BOVIN	GeneProduct	ENSBTAG00000005078 (Ensembl Cow)
UCHL3	GeneProduct	520170 (Entrez Gene)
Ubiquitin	Protein

Annotated Interactions