Metapathway biotransformation (Mus musculus)
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Reduction
Hydrolysis
Nucleophiles
N-acetyltransferases
Cytochrome P450
Amino acid conjugation
Electrophiles
Glutathione synthetase
Glutathione transferases
Glucuronidation
Acetylation
Epoxide hydrolases
Oxidation
Glutathione reductase
Glutathione conjugation
Methyltransferases
Glucuronosyltransferases
Sulfotransferases
Methylation
Sulfation
Aldo-keto reductases
Flavin monooxygenases
Glutathione peroxidases
Amino acid acyl transferases
UGT1A10
Kcnab2
Cyp4v3
Hs3st2
CYP2C9
UGT1A6
Nat9
Gstk1
Cyp39a1
CYP4F8
AKR1C3
HS3ST3A1
Cyp26b1
Baat
Chst1
Ndst2
Cyp24a1
Substrate=O
Cyp2s1
Sult4a1
Chst5
Substrate-Ac
CYP11B1
Chst3
UGT2A2
Cyp8b1
Gss
Kcnab1
Gstt2
Gstcd
GSTA2
AC122521.4
Ugt2a2
Gstz1
CYP3A5
GSTA4
Cyp11a1
Hnmt
Mgst1
Gpx2
Fmo3
Hs6st1
GSTA5
Cyp1a1
CYP3A43
Cyp2u1
AC161058.2-1
UGT1A5
Gal3st1
Chst5
Substrate-NH2
NAT1
Fmo2
HS3ST3B1
Hs6st3
CYP4F11
Ephx1
Cyp7a1
Cyp26c1
CYP2C19
Sulfotransferase
GSTM1
Amino acid acyltransferase
Gpx5
SULT1C2
Gstm7
CYP11B2
Gstt1
Gal3st3
Substrate-SO3H
AC140307.3-1
Hs6st2
Nat12
Chst10
Chst7
Ugt1a1
NAT8
CYP27C1
Comt1
UGT2B15
AC154274.1-1
Substrate-SG
Ndst3
GAL3ST2
AKR1C1
Chst4
Mgst3
Chst8
Gpx1
Sult2b1
Sult1a1
GLYATL2
Cyp46a1
Cyp2e1
Cyp21a1
CYP450
Cyp51
Fmo4
GSTA3
CYP2B6
Inmt
NAT2
Substrate-O-R
Xenobiotic substrate
Tpmt
Ugt2a3
Gpx4
Sult1a1
Gstt2
Gal3st4
UGT2B17
Nat6
Mgst2
CYP4F12
CYP2A7
Chst2
Gpx3
Flavin monooxygenase
Substrate-Gl
Glyat
Cyp26a1
Glutathione transferase
GSTM4
Substrate-Aa
CYP2A6
Akr7a5
Sult1a1
Sult1e1
Cyp1b1
Substrate-OH
Chst9
Cyp1a2
SULT1C3
GLYATL1
GSTP1
Cyp4f18
Glucuronosyltransferase
Chst11
UGT2B4
Gsto2
Hs3st4
Hs2st1
Gsr
Cyp2r1
UGT1A7
Hs3st1
Nat5
Cyp27a1
CYP3A4
Chst12
Ephx2
Ugt1a10
Cyp20a1
Hs3st6
CYP2A13
Cyp7b1
Cyp4b1
SULT1C4
Gstm5
Cyp2f2
N-acetyltransferase
Gsto1
Fmo1
Ndst1
Cyp4x1
GSTM5
Substrate-SH
UGT2B7
UGT2B11
Hs3st5
CYP2C18
AKR7A3
CYP2D6
Cyp19a1
Fmo5
Sult1b1
Sult1a1
UGT1A9
CYP2C8
Nat8l
Cyp17a1
Nat14
Ugt1a5
Substrate-CH3
Aldo-keto reductase
Nat10
Chst14
Kcnab3
Akr1b3
CYP4F2
Ndst4
SULT2A1
CYP2J2
AKR1B10
Cyp4f39
AKR1C2
Akr1d1
AKR1C4
GSTA1
CYP3A7
Akr1a4
Sult1c2
CYP4Z1
Cyp27b1
Ugt1a2
Nnmt
UGT2B28
Nat13
Methyltransferase
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 64% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
94721
view
14:08, 5 October 2017
Egonw
Converted two complexes (which they are not) to groups.
94720
view
14:04, 5 October 2017
Egonw
Mim-typed interactions.
69747
view
09:37, 11 July 2013
Egonw
Added ChEBI identifiers for a few compound classes.
69160
view
18:19, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67456
view
11:04, 26 June 2013
Ddigles
Ontology Term : 'cellular detoxification pathway' added !
59060
view
21:01, 21 February 2013
MaintBot
Updated Ensembl and UniProt data source
58513
view
19:13, 14 February 2013
MaintBot
Modified title
41349
view
00:26, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34408
view
23:07, 9 December 2009
MaintBot
Automatic update of empty xrefs
33190
view
18:06, 5 November 2009
Khanspers
Modified categories
32293
view
13:12, 15 August 2009
MaintBot
Fixed text labels
31856
view
12:33, 14 August 2009
MaintBot
Fixed group labels
31321
view
20:17, 13 August 2009
MaintBot
Fixed text labels
30847
view
00:06, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AC122521.4
GeneProduct
ENSMUSG00000056643 (Ensembl Mouse)
AC140307.3-1
GeneProduct
ENSMUSG00000024764 (Ensembl Mouse)
AC154274.1-1
GeneProduct
ENSMUSG00000038045 (Ensembl Mouse)
AC161058.2-1
GeneProduct
ENSMUSG00000029541 (Ensembl Mouse)
AKR1B10
GeneProduct
67861 (Entrez Gene)
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
AKR1C4
GeneProduct
AKR7A3
GeneProduct
Akr1a4
GeneProduct
ENSMUSG00000028692 (Ensembl Mouse)
Akr1b3
GeneProduct
ENSMUSG00000001642 (Ensembl Mouse)
Akr1d1
GeneProduct
ENSMUSG00000038641 (Ensembl Mouse)
Akr7a5
GeneProduct
ENSMUSG00000028743 (Ensembl Mouse)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
Baat
GeneProduct
ENSMUSG00000039653 (Ensembl Mouse)
CYP11B1
GeneProduct
110115 (Entrez Gene)
CYP11B2
GeneProduct
13072 (Entrez Gene)
CYP27C1
GeneProduct
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2B6
GeneProduct
CYP2C18
GeneProduct
CYP2C19
GeneProduct
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
CYP2J2
GeneProduct
CYP3A4
GeneProduct
CYP3A43
GeneProduct
CYP3A5
GeneProduct
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F2
GeneProduct
CYP4F8
GeneProduct
CYP4Z1
GeneProduct
Chst10
GeneProduct
ENSMUSG00000026080 (Ensembl Mouse)
Chst11
GeneProduct
ENSMUSG00000034612 (Ensembl Mouse)
Chst12
GeneProduct
ENSMUSG00000036599 (Ensembl Mouse)
Chst14
GeneProduct
72136 (Entrez Gene)
Chst1
GeneProduct
ENSMUSG00000027221 (Ensembl Mouse)
Chst2
GeneProduct
ENSMUSG00000033350 (Ensembl Mouse)
Chst3
GeneProduct
ENSMUSG00000057337 (Ensembl Mouse)
Chst4
GeneProduct
ENSMUSG00000035930 (Ensembl Mouse)
Chst5
GeneProduct
ENSMUSG00000031952 (Ensembl Mouse)
Chst7
GeneProduct
ENSMUSG00000037347 (Ensembl Mouse)
Chst8
GeneProduct
ENSMUSG00000060402 (Ensembl Mouse)
Chst9
GeneProduct
71367 (Entrez Gene)
Comt1
GeneProduct
ENSMUSG00000000326 (Ensembl Mouse)
Cyp11a1
GeneProduct
ENSMUSG00000032323 (Ensembl Mouse)
Cyp17a1
GeneProduct
ENSMUSG00000003555 (Ensembl Mouse)
Cyp19a1
GeneProduct
ENSMUSG00000032274 (Ensembl Mouse)
Cyp1a1
GeneProduct
ENSMUSG00000032315 (Ensembl Mouse)
Cyp1a2
GeneProduct
ENSMUSG00000032310 (Ensembl Mouse)
Cyp1b1
GeneProduct
ENSMUSG00000024087 (Ensembl Mouse)
Cyp20a1
GeneProduct
ENSMUSG00000049439 (Ensembl Mouse)
Cyp21a1
GeneProduct
13079 (Entrez Gene)
Cyp24a1
GeneProduct
ENSMUSG00000038567 (Ensembl Mouse)
Cyp26a1
GeneProduct
ENSMUSG00000024987 (Ensembl Mouse)
Cyp26b1
GeneProduct
ENSMUSG00000063415 (Ensembl Mouse)
Cyp26c1
GeneProduct
ENSMUSG00000062432 (Ensembl Mouse)
Cyp27a1
GeneProduct
ENSMUSG00000026170 (Ensembl Mouse)
Cyp27b1
GeneProduct
ENSMUSG00000006724 (Ensembl Mouse)
Cyp2e1
GeneProduct
ENSMUSG00000025479 (Ensembl Mouse)
Cyp2f2
GeneProduct
ENSMUSG00000052974 (Ensembl Mouse)
Cyp2r1
GeneProduct
ENSMUSG00000030670 (Ensembl Mouse)
Cyp2s1
GeneProduct
ENSMUSG00000040703 (Ensembl Mouse)
Cyp2u1
GeneProduct
ENSMUSG00000027983 (Ensembl Mouse)
Cyp39a1
GeneProduct
ENSMUSG00000023963 (Ensembl Mouse)
Cyp46a1
GeneProduct
ENSMUSG00000021259 (Ensembl Mouse)
Cyp4b1
GeneProduct
ENSMUSG00000028713 (Ensembl Mouse)
Cyp4f18
GeneProduct
ENSMUSG00000003484 (Ensembl Mouse)
Cyp4f39
GeneProduct
ENSMUSG00000061126 (Ensembl Mouse)
Cyp4v3
GeneProduct
ENSMUSG00000079057 (Ensembl Mouse)
Cyp4x1
GeneProduct
ENSMUSG00000047155 (Ensembl Mouse)
Cyp51
GeneProduct
ENSMUSG00000001467 (Ensembl Mouse)
Cyp7a1
GeneProduct
ENSMUSG00000028240 (Ensembl Mouse)
Cyp7b1
GeneProduct
ENSMUSG00000039519 (Ensembl Mouse)
Cyp8b1
GeneProduct
ENSMUSG00000050445 (Ensembl Mouse)
Ephx1
GeneProduct
ENSMUSG00000038776 (Ensembl Mouse)
Ephx2
GeneProduct
ENSMUSG00000022040 (Ensembl Mouse)
Flavin monooxygenase
GeneProduct
Fmo1
GeneProduct
ENSMUSG00000040181 (Ensembl Mouse)
Fmo2
GeneProduct
ENSMUSG00000040170 (Ensembl Mouse)
Fmo3
GeneProduct
ENSMUSG00000026691 (Ensembl Mouse)
Fmo4
GeneProduct
ENSMUSG00000026692 (Ensembl Mouse)
Fmo5
GeneProduct
ENSMUSG00000028088 (Ensembl Mouse)
GAL3ST2
GeneProduct
381334 (Entrez Gene)
GLYATL1
GeneProduct
GLYATL2
GeneProduct
GSTA1
GeneProduct
14857 (Entrez Gene)
GSTA2
GeneProduct
14858 (Entrez Gene)
GSTA3
GeneProduct
14859 (Entrez Gene)
GSTA4
GeneProduct
14860 (Entrez Gene)
GSTA5
GeneProduct
GSTM1
GeneProduct
14862 (Entrez Gene)
GSTM4
GeneProduct
14865 (Entrez Gene)
GSTM5
GeneProduct
14866 (Entrez Gene)
GSTP1
GeneProduct
14870 (Entrez Gene)
Gal3st1
GeneProduct
ENSMUSG00000049721 (Ensembl Mouse)
Gal3st3
GeneProduct
ENSMUSG00000047658 (Ensembl Mouse)
Gal3st4
GeneProduct
ENSMUSG00000075593 (Ensembl Mouse)
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
Glyat
GeneProduct
ENSMUSG00000063683 (Ensembl Mouse)
Gpx1
GeneProduct
ENSMUSG00000063856 (Ensembl Mouse)
Gpx2
GeneProduct
ENSMUSG00000042808 (Ensembl Mouse)
Gpx3
GeneProduct
ENSMUSG00000018339 (Ensembl Mouse)
Gpx4
GeneProduct
ENSMUSG00000075706 (Ensembl Mouse)
Gpx5
GeneProduct
ENSMUSG00000004344 (Ensembl Mouse)
Gsr
GeneProduct
ENSMUSG00000031584 (Ensembl Mouse)
Gss
GeneProduct
ENSMUSG00000027610 (Ensembl Mouse)
Gstcd
GeneProduct
ENSMUSG00000028018 (Ensembl Mouse)
Gstk1
GeneProduct
ENSMUSG00000029864 (Ensembl Mouse)
Gstm5
GeneProduct
ENSMUSG00000004032 (Ensembl Mouse)
Gstm7
GeneProduct
ENSMUSG00000004035 (Ensembl Mouse)
Gsto1
GeneProduct
ENSMUSG00000025068 (Ensembl Mouse)
Gsto2
GeneProduct
ENSMUSG00000025069 (Ensembl Mouse)
Gstt1
GeneProduct
ENSMUSG00000001663 (Ensembl Mouse)
Gstt2
GeneProduct
ENSMUSG00000033318 (Ensembl Mouse)
Gstz1
GeneProduct
ENSMUSG00000021033 (Ensembl Mouse)
HS3ST3A1
GeneProduct
15478 (Entrez Gene)
HS3ST3B1
GeneProduct
54710 (Entrez Gene)
Hnmt
GeneProduct
ENSMUSG00000026986 (Ensembl Mouse)
Hs2st1
GeneProduct
ENSMUSG00000040151 (Ensembl Mouse)
Hs3st1
GeneProduct
ENSMUSG00000051022 (Ensembl Mouse)
Hs3st2
GeneProduct
ENSMUSG00000046321 (Ensembl Mouse)
Hs3st4
GeneProduct
ENSMUSG00000078591 (Ensembl Mouse)
Hs3st5
GeneProduct
ENSMUSG00000044499 (Ensembl Mouse)
Hs3st6
GeneProduct
ENSMUSG00000039628 (Ensembl Mouse)
Hs6st1
GeneProduct
ENSMUSG00000045216 (Ensembl Mouse)
Hs6st2
GeneProduct
ENSMUSG00000062184 (Ensembl Mouse)
Hs6st3
GeneProduct
ENSMUSG00000053465 (Ensembl Mouse)
Inmt
GeneProduct
ENSMUSG00000003477 (Ensembl Mouse)
Kcnab1
GeneProduct
ENSMUSG00000027827 (Ensembl Mouse)
Kcnab2
GeneProduct
ENSMUSG00000028931 (Ensembl Mouse)
Kcnab3
GeneProduct
ENSMUSG00000018470 (Ensembl Mouse)
Methyltransferase
GeneProduct
Mgst1
GeneProduct
ENSMUSG00000008540 (Ensembl Mouse)
Mgst2
GeneProduct
ENSMUSG00000074604 (Ensembl Mouse)
Mgst3
GeneProduct
ENSMUSG00000026688 (Ensembl Mouse)
N-acetyltransferase
GeneProduct
NAT1
GeneProduct
NAT2
GeneProduct
17961 (Entrez Gene)
NAT8
GeneProduct
68396 (Entrez Gene)
Nat10
GeneProduct
ENSMUSG00000027185 (Ensembl Mouse)
Nat12
GeneProduct
ENSMUSG00000036282 (Ensembl Mouse)
Nat13
GeneProduct
ENSMUSG00000022698 (Ensembl Mouse)
Nat14
GeneProduct
ENSMUSG00000035285 (Ensembl Mouse)
Nat5
GeneProduct
ENSMUSG00000002728 (Ensembl Mouse)
Nat6
GeneProduct
ENSMUSG00000079334 (Ensembl Mouse)
Nat8l
GeneProduct
ENSMUSG00000048142 (Ensembl Mouse)
Nat9
GeneProduct
ENSMUSG00000015542 (Ensembl Mouse)
Ndst1
GeneProduct
ENSMUSG00000054008 (Ensembl Mouse)
Ndst2
GeneProduct
ENSMUSG00000039308 (Ensembl Mouse)
Ndst3
GeneProduct
ENSMUSG00000027977 (Ensembl Mouse)
Ndst4
GeneProduct
ENSMUSG00000027971 (Ensembl Mouse)
Nnmt
GeneProduct
ENSMUSG00000032271 (Ensembl Mouse)
SULT1C2
GeneProduct
69083 (Entrez Gene)
SULT1C3
GeneProduct
SULT1C4
GeneProduct
SULT2A1
GeneProduct
20859 (Entrez Gene)
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
Sult1a1
GeneProduct
ENSMUSG00000030711 (Ensembl Mouse)
Sult1b1
GeneProduct
ENSMUSG00000029269 (Ensembl Mouse)
Sult1c2
GeneProduct
ENSMUSG00000023122 (Ensembl Mouse)
Sult1e1
GeneProduct
ENSMUSG00000029272 (Ensembl Mouse)
Sult2b1
GeneProduct
ENSMUSG00000003271 (Ensembl Mouse)
Sult4a1
GeneProduct
ENSMUSG00000018865 (Ensembl Mouse)
Tpmt
GeneProduct
ENSMUSG00000021376 (Ensembl Mouse)
UGT1A10
GeneProduct
394430 (Entrez Gene)
UGT1A5
GeneProduct
394433 (Entrez Gene)
UGT1A6
GeneProduct
UGT1A7
GeneProduct
UGT1A9
GeneProduct
394434 (Entrez Gene)
UGT2A2
GeneProduct
552899 (Entrez Gene)
UGT2B11
GeneProduct
UGT2B15
GeneProduct
UGT2B17
GeneProduct
UGT2B28
GeneProduct
UGT2B4
GeneProduct
UGT2B7
GeneProduct
Ugt1a10
GeneProduct
ENSMUSG00000054545 (Ensembl Mouse)
Ugt1a1
GeneProduct
394436 (Entrez Gene)
Ugt1a2
GeneProduct
22236 (Entrez Gene)
Ugt1a5
GeneProduct
394433 (Entrez Gene)
Ugt2a2
GeneProduct
ENSMUSG00000029268 (Ensembl Mouse)
Ugt2a3
GeneProduct
ENSMUSG00000035780 (Ensembl Mouse)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions