Phase I biotransformations, non-P450 (Equus caballus)

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1OHOHHydrolysisOHOHcarboxylic acid esterscarboxylic acid estersPhosphoric acid estersPhosphoric acid estersamidesCES7thio estersXP_001490246.1XP_001494227.2A6P3C7_HORSEXP_001493453.2XP_001493507.1thio estersCES1amidesXP_001915822.1


Description

This pathway lists several phase 1 biotransformations and their related enzymes. NOTE: This pathway is incomplete, reduction and oxidation enzymes are missing

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP136(r29886) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Klaassen, C.D., Watkins III, J.B.; ''Casarett & Doull's Essentials of Toxicology''; , 2003

History

View all...
CompareRevisionActionTimeUserComment
128193view00:35, 29 January 2024EweitzModified title
125265view12:56, 31 January 2023LarsgwAdd ISBN to publication
107102view14:18, 17 September 2019MaintBotChEBI identifier normalization
95740view13:30, 19 January 2018Mkutmonupdated homology conversion
88306view15:28, 1 August 2016FehrhartOntology Term : 'cytochrome P450-independent phase I biotransformation pathway' added !
73514view23:19, 29 January 2014KhanspersModified title
68737view22:49, 6 July 2013MaintBotUpdated to 2013 gpml schema
58870view00:33, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
40909view22:41, 1 March 2011MaintBotRemoved redundant pathway information and comments
31822view12:24, 14 August 2009MaintBotFixed group labels
30782view23:32, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A6P3C7_HORSEGeneProductENSECAG00000010840 (Ensembl)
CES1GeneProduct
CES7GeneProductENSECAG00000010588 (Ensembl)
Phosphoric acid estersMetabolite
XP_001490246.1GeneProductENSECAG00000024350 (Ensembl)
XP_001493453.2GeneProductENSECAG00000000344 (Ensembl)
XP_001493507.1GeneProductENSECAG00000009974 (Ensembl)
XP_001494227.2GeneProductENSECAG00000010414 (Ensembl)
XP_001915822.1GeneProductENSECAG00000012061 (Ensembl)
amidesMetabolite32988 (ChEBI)
carboxylic acid estersMetabolite
thio estersMetabolite

Annotated Interactions

No annotated interactions
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