Metapathway biotransformation (Mus musculus)

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Revision as of 11:04, 26 June 2013 by Ddigles (Talk | contribs)
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MethylationMethyltransferasesSulfotransferasesFlavin monooxygenasesReductionHydrolysisGlutathione synthetaseGlucuronidationGlucuronosyltransferasesAmino acid acyl transferasesGlutathione transferasesGlutathione reductaseCytochrome P450NucleophilesElectrophilesAmino acid conjugationAldo-keto reductasesN-acetyltransferasesGlutathione conjugationGlutathione peroxidasesAcetylationOxidationSulfationEpoxide hydrolasesAC122521.4SulfotransferaseEphx1Cyp20a1Comt1GSTA3Substrate-SHUGT2B7Chst9Substrate-CH3Ugt2a3Mgst2Sult1a1Sult1b1Cyp21a1Gpx1UGT2B4Substrate-SGCyp1a2BaatChst3CYP2A7Substrate-AaCyp4f18Gal3st1Akr7a5N-acetyltransferaseChst14Gstm5CYP2C19CYP2A6CYP4F11UGT2B17CYP2J2Substrate-GlGsto2Gpx3Cyp27a1UGT1A5CYP2C9Gpx2CYP3A7Substrate-AcUGT2A2Kcnab3Chst8CYP4F8Ugt1a10CYP2D6Sult1e1Akr1b3Ndst4HS3ST3B1Gsto1UGT2B11AKR1C1Sult4a1CYP11B2Hs3st5Cyp27b1GlucuronosyltransferaseGSTA4Hs6st1CYP3A5AKR1B10AC140307.3-1Cyp24a1GSTM1Hs6st2Cyp1a1GLYATL1TpmtNAT1Sult1a1Cyp8b1Cyp19a1Gstt1Cyp2f2Sult1a1Sult1a1UGT2B15Chst5CYP4F12Hs6st3CYP2B6Hs3st1Ugt1a5Chst4GlyatFmo3UGT1A9Cyp51InmtGstz1CYP2A13Substrate-NH2CYP2C8Cyp26c1Chst2Nat9NnmtMethyltransferaseGstk1CYP4Z1GSTP1Cyp26b1Hs3st4GLYATL2Ndst1Glutathione transferaseSubstrate-SO3HGAL3ST2NAT8AC161058.2-1GSTA1Cyp4x1Hs3st2Cyp7b1CYP3A4NAT2UGT2B28Akr1a4Fmo4Amino acid acyltransferaseSubstrate=OSULT2A1AKR1C2GSTA2GsrNat6Nat14Sult2b1Gpx5Ndst2Cyp7a1UGT1A10Akr1d1Gpx4CYP3A43Nat12HnmtCyp17a1Gal3st3Cyp11a1CYP2C18Chst10SULT1C3Xenobiotic substrateGstm7Chst11Cyp4v3AC154274.1-1UGT1A6Nat13Flavin monooxygenaseGSTM5Cyp4f39Sult1c2Cyp39a1Ephx2Ndst3Cyp4b1Gal3st4Hs2st1GssGSTM4Fmo2Substrate-OHAKR7A3Gstt2Cyp2r1SULT1C2Nat10Substrate-O-RNat5Cyp2s1Kcnab2Chst12GstcdCYP27C1Fmo5Ugt1a1Aldo-keto reductaseCyp2u1Cyp46a1CYP4F2Chst7Ugt2a2Chst1Mgst1Cyp1b1Mgst3AKR1C3UGT1A7Kcnab1Hs3st6Gstt2CYP450Nat8lCYP11B1Cyp26a1Chst5Fmo1HS3ST3A1SULT1C4Ugt1a2GSTA5Cyp2e1AKR1C4


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 64% conversion rate.

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
94721view14:08, 5 October 2017EgonwConverted two complexes (which they are not) to groups.
94720view14:04, 5 October 2017EgonwMim-typed interactions.
69747view09:37, 11 July 2013EgonwAdded ChEBI identifiers for a few compound classes.
69160view18:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67456view11:04, 26 June 2013DdiglesOntology Term : 'cellular detoxification pathway' added !
59060view21:01, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
58513view19:13, 14 February 2013MaintBotModified title
41349view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
34408view23:07, 9 December 2009MaintBotAutomatic update of empty xrefs
33190view18:06, 5 November 2009KhanspersModified categories
32293view13:12, 15 August 2009MaintBotFixed text labels
31856view12:33, 14 August 2009MaintBotFixed group labels
31321view20:17, 13 August 2009MaintBotFixed text labels
30847view00:06, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AC122521.4GeneProductENSMUSG00000056643 (Ensembl)
AC140307.3-1GeneProductENSMUSG00000024764 (Ensembl)
AC154274.1-1GeneProductENSMUSG00000038045 (Ensembl)
AC161058.2-1GeneProductENSMUSG00000029541 (Ensembl)
AKR1B10GeneProduct67861 (Entrez Gene)
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
AKR7A3GeneProduct
Akr1a4GeneProductENSMUSG00000028692 (Ensembl)
Akr1b3GeneProductENSMUSG00000001642 (Ensembl)
Akr1d1GeneProductENSMUSG00000038641 (Ensembl)
Akr7a5GeneProductENSMUSG00000028743 (Ensembl)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
BaatGeneProductENSMUSG00000039653 (Ensembl)
CYP11B1GeneProduct110115 (Entrez Gene)
CYP11B2GeneProduct13072 (Entrez Gene)
CYP27C1GeneProduct
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2B6GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct
CYP2J2GeneProduct
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F8GeneProduct
CYP4Z1GeneProduct
Chst10GeneProductENSMUSG00000026080 (Ensembl)
Chst11GeneProductENSMUSG00000034612 (Ensembl)
Chst12GeneProductENSMUSG00000036599 (Ensembl)
Chst14GeneProduct72136 (Entrez Gene)
Chst1GeneProductENSMUSG00000027221 (Ensembl)
Chst2GeneProductENSMUSG00000033350 (Ensembl)
Chst3GeneProductENSMUSG00000057337 (Ensembl)
Chst4GeneProductENSMUSG00000035930 (Ensembl)
Chst5GeneProductENSMUSG00000031952 (Ensembl)
Chst7GeneProductENSMUSG00000037347 (Ensembl)
Chst8GeneProductENSMUSG00000060402 (Ensembl)
Chst9GeneProduct71367 (Entrez Gene)
Comt1GeneProductENSMUSG00000000326 (Ensembl)
Cyp11a1GeneProductENSMUSG00000032323 (Ensembl)
Cyp17a1GeneProductENSMUSG00000003555 (Ensembl)
Cyp19a1GeneProductENSMUSG00000032274 (Ensembl)
Cyp1a1GeneProductENSMUSG00000032315 (Ensembl)
Cyp1a2GeneProductENSMUSG00000032310 (Ensembl)
Cyp1b1GeneProductENSMUSG00000024087 (Ensembl)
Cyp20a1GeneProductENSMUSG00000049439 (Ensembl)
Cyp21a1GeneProduct13079 (Entrez Gene)
Cyp24a1GeneProductENSMUSG00000038567 (Ensembl)
Cyp26a1GeneProductENSMUSG00000024987 (Ensembl)
Cyp26b1GeneProductENSMUSG00000063415 (Ensembl)
Cyp26c1GeneProductENSMUSG00000062432 (Ensembl)
Cyp27a1GeneProductENSMUSG00000026170 (Ensembl)
Cyp27b1GeneProductENSMUSG00000006724 (Ensembl)
Cyp2e1GeneProductENSMUSG00000025479 (Ensembl)
Cyp2f2GeneProductENSMUSG00000052974 (Ensembl)
Cyp2r1GeneProductENSMUSG00000030670 (Ensembl)
Cyp2s1GeneProductENSMUSG00000040703 (Ensembl)
Cyp2u1GeneProductENSMUSG00000027983 (Ensembl)
Cyp39a1GeneProductENSMUSG00000023963 (Ensembl)
Cyp46a1GeneProductENSMUSG00000021259 (Ensembl)
Cyp4b1GeneProductENSMUSG00000028713 (Ensembl)
Cyp4f18GeneProductENSMUSG00000003484 (Ensembl)
Cyp4f39GeneProductENSMUSG00000061126 (Ensembl)
Cyp4v3GeneProductENSMUSG00000079057 (Ensembl)
Cyp4x1GeneProductENSMUSG00000047155 (Ensembl)
Cyp51GeneProductENSMUSG00000001467 (Ensembl)
Cyp7a1GeneProductENSMUSG00000028240 (Ensembl)
Cyp7b1GeneProductENSMUSG00000039519 (Ensembl)
Cyp8b1GeneProductENSMUSG00000050445 (Ensembl)
Ephx1GeneProductENSMUSG00000038776 (Ensembl)
Ephx2GeneProductENSMUSG00000022040 (Ensembl)
Flavin monooxygenaseGeneProduct
Fmo1GeneProductENSMUSG00000040181 (Ensembl)
Fmo2GeneProductENSMUSG00000040170 (Ensembl)
Fmo3GeneProductENSMUSG00000026691 (Ensembl)
Fmo4GeneProductENSMUSG00000026692 (Ensembl)
Fmo5GeneProductENSMUSG00000028088 (Ensembl)
GAL3ST2GeneProduct381334 (Entrez Gene)
GLYATL1GeneProduct
GLYATL2GeneProduct
GSTA1GeneProduct14857 (Entrez Gene)
GSTA2GeneProduct14858 (Entrez Gene)
GSTA3GeneProduct14859 (Entrez Gene)
GSTA4GeneProduct14860 (Entrez Gene)
GSTA5GeneProduct
GSTM1GeneProduct14862 (Entrez Gene)
GSTM4GeneProduct14865 (Entrez Gene)
GSTM5GeneProduct14866 (Entrez Gene)
GSTP1GeneProduct14870 (Entrez Gene)
Gal3st1GeneProductENSMUSG00000049721 (Ensembl)
Gal3st3GeneProductENSMUSG00000047658 (Ensembl)
Gal3st4GeneProductENSMUSG00000075593 (Ensembl)
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
GlyatGeneProductENSMUSG00000063683 (Ensembl)
Gpx1GeneProductENSMUSG00000063856 (Ensembl)
Gpx2GeneProductENSMUSG00000042808 (Ensembl)
Gpx3GeneProductENSMUSG00000018339 (Ensembl)
Gpx4GeneProductENSMUSG00000075706 (Ensembl)
Gpx5GeneProductENSMUSG00000004344 (Ensembl)
GsrGeneProductENSMUSG00000031584 (Ensembl)
GssGeneProductENSMUSG00000027610 (Ensembl)
GstcdGeneProductENSMUSG00000028018 (Ensembl)
Gstk1GeneProductENSMUSG00000029864 (Ensembl)
Gstm5GeneProductENSMUSG00000004032 (Ensembl)
Gstm7GeneProductENSMUSG00000004035 (Ensembl)
Gsto1GeneProductENSMUSG00000025068 (Ensembl)
Gsto2GeneProductENSMUSG00000025069 (Ensembl)
Gstt1GeneProductENSMUSG00000001663 (Ensembl)
Gstt2GeneProductENSMUSG00000033318 (Ensembl)
Gstz1GeneProductENSMUSG00000021033 (Ensembl)
HS3ST3A1GeneProduct15478 (Entrez Gene)
HS3ST3B1GeneProduct54710 (Entrez Gene)
HnmtGeneProductENSMUSG00000026986 (Ensembl)
Hs2st1GeneProductENSMUSG00000040151 (Ensembl)
Hs3st1GeneProductENSMUSG00000051022 (Ensembl)
Hs3st2GeneProductENSMUSG00000046321 (Ensembl)
Hs3st4GeneProductENSMUSG00000078591 (Ensembl)
Hs3st5GeneProductENSMUSG00000044499 (Ensembl)
Hs3st6GeneProductENSMUSG00000039628 (Ensembl)
Hs6st1GeneProductENSMUSG00000045216 (Ensembl)
Hs6st2GeneProductENSMUSG00000062184 (Ensembl)
Hs6st3GeneProductENSMUSG00000053465 (Ensembl)
InmtGeneProductENSMUSG00000003477 (Ensembl)
Kcnab1GeneProductENSMUSG00000027827 (Ensembl)
Kcnab2GeneProductENSMUSG00000028931 (Ensembl)
Kcnab3GeneProductENSMUSG00000018470 (Ensembl)
MethyltransferaseGeneProduct
Mgst1GeneProductENSMUSG00000008540 (Ensembl)
Mgst2GeneProductENSMUSG00000074604 (Ensembl)
Mgst3GeneProductENSMUSG00000026688 (Ensembl)
N-acetyltransferaseGeneProduct
NAT1GeneProduct
NAT2GeneProduct17961 (Entrez Gene)
NAT8GeneProduct68396 (Entrez Gene)
Nat10GeneProductENSMUSG00000027185 (Ensembl)
Nat12GeneProductENSMUSG00000036282 (Ensembl)
Nat13GeneProductENSMUSG00000022698 (Ensembl)
Nat14GeneProductENSMUSG00000035285 (Ensembl)
Nat5GeneProductENSMUSG00000002728 (Ensembl)
Nat6GeneProductENSMUSG00000079334 (Ensembl)
Nat8lGeneProductENSMUSG00000048142 (Ensembl)
Nat9GeneProductENSMUSG00000015542 (Ensembl)
Ndst1GeneProductENSMUSG00000054008 (Ensembl)
Ndst2GeneProductENSMUSG00000039308 (Ensembl)
Ndst3GeneProductENSMUSG00000027977 (Ensembl)
Ndst4GeneProductENSMUSG00000027971 (Ensembl)
NnmtGeneProductENSMUSG00000032271 (Ensembl)
SULT1C2GeneProduct69083 (Entrez Gene)
SULT1C3GeneProduct
SULT1C4GeneProduct
SULT2A1GeneProduct20859 (Entrez Gene)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
Sult1a1GeneProductENSMUSG00000030711 (Ensembl)
Sult1b1GeneProductENSMUSG00000029269 (Ensembl)
Sult1c2GeneProductENSMUSG00000023122 (Ensembl)
Sult1e1GeneProductENSMUSG00000029272 (Ensembl)
Sult2b1GeneProductENSMUSG00000003271 (Ensembl)
Sult4a1GeneProductENSMUSG00000018865 (Ensembl)
TpmtGeneProductENSMUSG00000021376 (Ensembl)
UGT1A10GeneProduct394430 (Entrez Gene)
UGT1A5GeneProduct394433 (Entrez Gene)
UGT1A6GeneProduct
UGT1A7GeneProduct
UGT1A9GeneProduct394434 (Entrez Gene)
UGT2A2GeneProduct552899 (Entrez Gene)
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
Ugt1a10GeneProductENSMUSG00000054545 (Ensembl)
Ugt1a1GeneProduct394436 (Entrez Gene)
Ugt1a2GeneProduct22236 (Entrez Gene)
Ugt1a5GeneProduct394433 (Entrez Gene)
Ugt2a2GeneProductENSMUSG00000029268 (Ensembl)
Ugt2a3GeneProductENSMUSG00000035780 (Ensembl)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1251"
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