Folic acid biosynthesis (Saccharomyces cerevisiae)
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Christine Chichester
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5,10-methenyl-THF
2-amino-4-hydroxy-6-hydroxymethyl-
formate
THF
7,8-dihydrofolate
7,8-dihydropteridine
AMP
H4PteGlu(n)
2 H2O
7,8-dihydropteroate
NADP
dihydoneopterin triphosphate
H4PteGlu(n+1)
H2O
2-amino-4-hydroxy-6-hydroxymethyl-
pyruvate
NADP
dihydoneopterin triphosphate
7,8-dihydropteridine diphosphate
4-amino-4-deoxychorismate
glycoaldehyde
dyhydro-neo-pterin
p-aminobenzoate
formate
AMP
H2O
phosphate
ADP
ATP
ADP
L-serine
FOL1
MIS1
ATP
MIS1
YMR289W
L-glutamate
phosphate
phosphate
MET7
L-glutamate
SHM1
ABZ1
5,10-methylene-THF
ADE3
FOL1
L-glutamate
FOL2
FOL1
ATP
FOL3
NADPH
ATP
phosphate
SHM2
L-glycine
MIS1
L-glutamine
GTP
pyrophosphate
ADE3
pyrophosphate
NADPH
chorismate
ADE3
10-formyl-THF
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Quality Tags
Ontology Terms
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Bibliography
''folate biosynthesis II''; https://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-45,
History
View all...
Compare
Revision
Action
Time
User
Comment
130580
view
00:26, 29 May 2024
Khanspers
Modified description
130577
view
00:26, 29 May 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
130576
view
00:25, 29 May 2024
Khanspers
overhaul: updated interactions, removed incorrect parts, added xrefs for metabolites and enzymes
107265
view
14:36, 17 September 2019
MaintBot
ChEBI identifier normalization
92970
view
17:38, 21 July 2017
Khanspers
Modified description
92969
view
17:38, 21 July 2017
Khanspers
removed GenMAPP notes
92925
view
14:31, 18 July 2017
DeSl
Changed CAS to correct ChEBI ID.
89693
view
10:12, 26 September 2016
Egonw
Replace the CAS number of the salt with that of just the metabolite.
69957
view
20:52, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69587
view
20:30, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67253
view
10:27, 26 June 2013
Christine Chichester
Ontology Term : 'pathway of folate cycle/metabolism' added !
41813
view
04:49, 2 March 2011
MaintBot
Removed redundant pathway information and comments
21848
view
11:32, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:Folic Acid Biosynthesis]] moved to [[Pathway:WP555]]: Moved to stable identifier
12706
view
07:59, 17 May 2008
MaintBot
automated metabolite conversion
8717
view
14:07, 7 January 2008
MaintBot
Added to category $category
8715
view
14:07, 7 January 2008
J.Heckman
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
10-formyl-THF
2800-34-2 (CAS)
5,10-methylene-THF
31690-11-6 (CAS)
ABZ1
GeneProduct
S000005316 (SGD)
ADE3
GeneProduct
S000003436 (SGD)
ADP
58-64-0 (CAS)
ATP
1927-31-7 (CAS)
FOL1
GeneProduct
S000005200 (SGD)
FOL2
GeneProduct
S000003499 (SGD)
FOL3
GeneProduct
S000004719 (SGD)
GTP
2564-35-4 (CAS)
L-glutamate
56-86-0 (CAS)
L-glutamine
56-85-9 (CAS)
L-glycine
56-40-6 (CAS)
L-serine
56-45-1 (CAS)
MET7
GeneProduct
S000005767 (SGD)
MIS1
GeneProduct
S000000288 (SGD)
NADPH
2646-71-1 (CAS)
SHM1
GeneProduct
S000000467 (SGD)
SHM2
GeneProduct
S000004048 (SGD)
YMR289W
GeneProduct
S000004902 (SGD)
chorismate
55508-12-8 (CAS)
phosphate
14265-44-2 (CAS)
pyrophosphate
2466-09-3 (CAS)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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