De novo NAD biosynthesis (Saccharomyces cerevisiae)
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H2O
AMP
H2O
2-amino-3-carboxymuconate semialdehyde
O2
O2
quinolinate
NAD
deamido-NAD
O2
H2O
nicotinate nucleotide
spontaneous
3-hydroxy-anthranilate
H2O
CO2
H2O
NADP
formate
L-glutamine
ATP
BNA3
BNA6
BNA5
3-hydroxy-L-kynurenine
BNA2
PRPP
NMA2
pyrophosphate
L-Formylkynurenine
NMA1
pyrophosphate
BNA1
QNS1
ATP
BNA4
L-tryptophan
kynurenine
pyrophosphate
L-glutamate
NADPH
L-alanine
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Quality Tags
Ontology Terms
Saving...
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Bibliography
''NAD de novo biosynthesis II (from tryptophan)''; YeastPathways,
History
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Revision
Action
Time
User
Comment
135457
view
22:24, 5 September 2024
Khanspers
Modified description
135456
view
22:21, 5 September 2024
Khanspers
lit ref
135455
view
22:20, 5 September 2024
Khanspers
added lit ref
135305
view
23:46, 15 August 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
135304
view
23:45, 15 August 2024
Khanspers
fix interactions, add metabolite ids, layout
117291
view
11:03, 20 May 2021
Eweitz
Modified title
92995
view
18:21, 21 July 2017
Khanspers
Modified description
92994
view
18:21, 21 July 2017
Khanspers
removed GenMAPP notes
92894
view
19:08, 14 July 2017
Egonw
Replace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
89707
view
06:57, 27 September 2016
Egonw
Replace the CAS number of the salt with that of just the metabolite.
69942
view
20:17, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69623
view
20:34, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67145
view
10:12, 26 June 2013
Christine Chichester
Ontology Term : 'de novo nicotinamide adenine dinucleotide biosynthetic pathway' added !
41858
view
04:51, 2 March 2011
MaintBot
Removed redundant pathway information and comments
21818
view
11:32, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:De Novo NAD Biosynthesis]] moved to [[Pathway:WP541]]: Moved to stable identifier
12688
view
07:58, 17 May 2008
MaintBot
automated metabolite conversion
8693
view
14:06, 7 January 2008
MaintBot
Added to category $category
8691
view
14:06, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
3-hydroxy-L-kynurenine
Metabolite
606-14-4 (CAS)
ATP
Metabolite
1927-31-7 (CAS)
BNA1
GeneProduct
S000003786 (SGD)
BNA2
GeneProduct
S000003839 (SGD)
BNA3
GeneProduct
S000003596 (SGD)
BNA4
GeneProduct
S000000194 (SGD)
BNA5
GeneProduct
S000004221 (SGD)
BNA6
GeneProduct
S000001943 (SGD)
L-Formylkynurenine
Metabolite
1022-31-7 (CAS)
L-alanine
Metabolite
6912-68-1 (CAS)
L-glutamate
Metabolite
56-86-0 (CAS)
L-glutamine
Metabolite
56-85-9 (CAS)
L-tryptophan
Metabolite
73-22-3 (CAS)
NADPH
Metabolite
2646-71-1 (CAS)
NMA1
GeneProduct
S000004320 (SGD)
NMA2
GeneProduct
S000003242 (SGD)
PRPP
Metabolite
97-55-2 (CAS)
QNS1
GeneProduct
S000001116 (SGD)
kynurenine
Metabolite
343-65-7 (CAS)
pyrophosphate
Metabolite
2466-09-3 (CAS)
Annotated Interactions
No annotated interactions
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