Irinotecan pathway (Homo sapiens)

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This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

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CompareRevisionActionTimeUserComment
128658view23:22, 17 February 2024EweitzGive more space
128657view23:21, 17 February 2024EweitzGive more space
128656view23:17, 17 February 2024EweitzMitigate site-PathVisio graphics discrepancy
128655view23:15, 17 February 2024EweitzUpgrade disease nodes
128654view23:08, 17 February 2024EweitzEconomize layout
128274view00:37, 30 January 2024EweitzStandardize case
123644view09:35, 8 August 2022DeSlOntology Term : 'DOID:0070113' removed !
123643view09:34, 8 August 2022DeSlConverted NPC1 protein to NPS (metabolite), updated annotation and releated interactions.
123642view09:28, 8 August 2022DeSlUpdated not UTF-8 encoded ref
123641view09:26, 8 August 2022DeSlUpdated two more arrows to mim-catalysis for protein interactions with mimconversions
123640view09:25, 8 August 2022DeSlUpdate arrows to MIM-translocation or conversion, and connect proteins correctly with mim-catalysis
116612view09:42, 9 May 2021EweitzModified title
115612view16:11, 1 March 2021DeSlOntology Term : 'Niemann-Pick disease type C1' added !
115611view16:10, 1 March 2021DeSlAdded niemann picks disease
106624view20:51, 12 September 2019KhanspersModified description
105631view05:03, 10 August 2019KhanspersModified description
101954view21:30, 20 November 2018EgonwRemoved whitespace in PubMed identifiers.
96294view15:59, 7 March 2018DeSlChanged layout
96094view19:23, 15 February 2018EgonwFixed data node typing.
96057view16:51, 15 February 2018EgonwFixed the APC identifier.
96003view09:23, 15 February 2018DeSlChanged literature ref (couldn't recognize symbol "í"
96002view09:22, 15 February 2018DeSlChanged literature ref (couldn't recognize symbol "é")
96001view09:20, 15 February 2018DeSlRemoved licence number
96000view09:16, 15 February 2018DeSlChnaged visualisation of enzymes, small layout changes.
93199view15:56, 2 August 2017DeSlReplaced NPC1 node, since the appearance was of metabolite, even though the node was a gene...
93196view15:39, 2 August 2017DeSlChamged appaerence of NPC1 gene (looked like metabolite)
93192view15:08, 2 August 2017DeSlAdded ID for SN-38G and added molecular weight for M4 (unknown metabolite)
93188view14:52, 2 August 2017DeSlAdded CHEBI: for IDnumber of SN-38
93187view14:51, 2 August 2017DeSlChanged CheMBL compound IDs for irinotecan+SN-38 to ChEBI's
68389view10:22, 4 July 2013EgonwFixed the DataNode type of two nodes with gene identifiers.
67410view10:58, 26 June 2013DdiglesOntology Term : 'irinotecan drug pathway' added !
63225view21:03, 8 May 2013MaintBotUpdating gpml version
46359view20:12, 19 January 2012KhanspersOntology Term : 'enterocyte' added !
46358view20:11, 19 January 2012KhanspersOntology Term : 'hepatocyte' added !
46357view20:09, 19 January 2012KhanspersOntology Term : 'diarrhea' added !
46356view20:09, 19 January 2012KhanspersOntology Term : 'neutropenia' added !
46355view20:08, 19 January 2012KhanspersOntology Term : 'DOID:0000405' removed !
46354view20:07, 19 January 2012KhanspersFInished references
46353view20:04, 19 January 2012KhanspersCleaned up references
46352view20:00, 19 January 2012KhanspersAdded references
46351view19:37, 19 January 2012KhanspersChanged metaboliote colors, added xrefs
46343view01:07, 19 January 2012Khansperschanged layout and added xrefs
44876view10:03, 6 October 2011MartijnVanIerselOntology Term : 'cancer' added !
41131view23:38, 1 March 2011MaintBotRemoved redundant pathway information and comments
38882view18:57, 24 September 2010Khanspers
38757view22:45, 23 September 2010KhanspersChanged compartments and line types
35492view13:04, 12 February 2010ThomasModified description
35491view13:03, 12 February 2010Thomasadded literature, removed genmapp comments
34493view22:13, 16 December 2009KhanspersAdded connectors
34492view22:08, 16 December 2009Khanspersminor edits

Error details 

exception 'MWException' with message 'Invalid pvjson, so cannot savePvjsonCache.' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1277
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(584): Pathway->savePvjsonCache()
#1 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(295): Pathway->getPvjson()
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(169): PathwayPage->Diagram()
#3 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(24): PathwayPage->render()
#4 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#5 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#6 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#7 /var/www/wikipathways/includes/Article.php(3406): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 7479)
#8 /var/www/wikipathways/includes/Article.php(875): Article->outputWikiText('<?xml version="...', false)
#9 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#10 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#11 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#12 {main}
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