Proteasome degradation (Drosophila melanogaster)

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Ubiquitin/E2 ComplexBeta subunitsE3/ProteinLid subunitsATPAMP Ubiquitin/E1 ComplexAlpha subunitsActivators ofCatalytic Core (p45)20S ComplexProteins to be DegradedPresentation by MHC class 1Intact Proteinsp45 ATPase SubunitCytosolic ProteinsOxidatively DamagedUbiquitin/ProteinDegrades only Peptides(PA700) (ATP dependent)Proteasome 20SUnfolds and DegradesProteasome 26 SPros35PSMD10CG6370Pros25PSMB8PSME1UBE1LH2AFZCG33303Rpn2HLA-BCG12096l(2)05070HLA-ADox-A2Rpn6UBE2BPros26Prosbeta5PSMB10Pros45Prosbeta2PSMA7HIST1H2ABProsMA5Pros26.4UBE2D1HLA-GPSME2HLA-CPros54Uba1Rpn12UBE2D2HLA-JRpn7Rpn9Rpt1H2AFXHLA-HRpn5REGPSMB9CG9588PSMA6effMov34NEDD4Prosalpha7Tbp-1Rpt3Rpt4Prosbeta3HLA-FCG12000CG17331Pros29Rpn1IFNGPros45Ubi-p63EHLA-E


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116929view09:46, 16 May 2021EweitzModified title
79434view02:57, 22 March 2015Khanspersupdate schema
79433view02:56, 22 March 2015KhanspersReverted to version '11:33, 26 June 2013' by Khanspers
77443view20:28, 8 September 2014MaintBotremoved old homology label
71516view19:22, 17 October 2013MaintBotAutomated update of data sources
68725view21:59, 6 July 2013MaintBotUpdated to 2013 gpml schema
67612view11:33, 26 June 2013DdiglesOntology Term : 'ubiquitin/proteasome degradation pathway' added !
40900view22:35, 1 March 2011MaintBotRemoved redundant pathway information and comments
21271view11:31, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Proteasome Degradation]] moved to [[Pathway:WP281]]: Moved to stable identifier
9026view14:15, 7 January 2008MaintBotAdded to category $category
9024view14:14, 7 January 2008NsalomonisUploaded new pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CG12000GeneProduct40639 (Entrez Gene)
CG12096GeneProduct32269 (Entrez Gene)
CG17331GeneProduct34999 (Entrez Gene)
CG33303GeneProduct2768916 (Entrez Gene)
CG6370GeneProduct37029 (Entrez Gene)
CG9588GeneProduct41672 (Entrez Gene)
Dox-A2GeneProduct35176 (Entrez Gene)
H2AFXGeneProduct (Entrez Gene)
H2AFZGeneProduct (Entrez Gene)
HIST1H2ABGeneProduct (Entrez Gene)
HLA-AGeneProduct (Entrez Gene)
HLA-BGeneProduct (Entrez Gene)
HLA-CGeneProduct (Entrez Gene)
HLA-EGeneProduct (Entrez Gene)
HLA-FGeneProduct (Entrez Gene)
HLA-GGeneProduct (Entrez Gene)
HLA-HGeneProduct (Entrez Gene)
HLA-JGeneProduct (Entrez Gene)
IFNGGeneProduct (Entrez Gene)
Mov34GeneProduct37894 (Entrez Gene)
NEDD4GeneProduct (Entrez Gene)
PSMA6GeneProduct (Entrez Gene)
PSMA7GeneProduct (Entrez Gene)
PSMB10GeneProduct (Entrez Gene)
PSMB8GeneProduct (Entrez Gene)
PSMB9GeneProduct (Entrez Gene)
PSMD10GeneProduct (Entrez Gene)
PSME1GeneProduct (Entrez Gene)
PSME2GeneProduct (Entrez Gene)
Pros25GeneProduct41531 (Entrez Gene)
Pros26.4GeneProduct42828 (Entrez Gene)
Pros26GeneProduct39855 (Entrez Gene)
Pros29GeneProduct37378 (Entrez Gene)
Pros35GeneProduct34359 (Entrez Gene)
Pros45GeneProduct33105 (Entrez Gene) PRS6_HUMAN
Pros54GeneProduct40388 (Entrez Gene)
ProsMA5GeneProduct36951 (Entrez Gene)
Prosalpha7GeneProduct36018 (Entrez Gene)
Prosbeta2GeneProduct39628 (Entrez Gene)
Prosbeta3GeneProduct41079 (Entrez Gene)
Prosbeta5GeneProduct45269 (Entrez Gene)
REGGeneProduct32274 (Entrez Gene)
Rpn12GeneProduct39845 (Entrez Gene)
Rpn1GeneProduct40174 (Entrez Gene)
Rpn2GeneProduct43449 (Entrez Gene)
Rpn5GeneProduct40717 (Entrez Gene)
Rpn6GeneProduct36638 (Entrez Gene)
Rpn7GeneProduct42641 (Entrez Gene)
Rpn9GeneProduct42802 (Entrez Gene)
Rpt1GeneProduct35701 (Entrez Gene)
Rpt3GeneProduct32047 (Entrez Gene) PRS6_HUMAN
Rpt4GeneProduct31567 (Entrez Gene)
Tbp-1GeneProduct42805 (Entrez Gene)
UBE1LGeneProduct (Entrez Gene)
UBE2BGeneProduct (Entrez Gene)
UBE2D1GeneProduct (Entrez Gene)
UBE2D2GeneProduct (Entrez Gene)
Uba1GeneProduct35998 (Entrez Gene)
Ubi-p63EGeneProduct38456 (Entrez Gene)
effGeneProduct41785 (Entrez Gene)
l(2)05070GeneProduct46058 (Entrez Gene) U13393

Annotated Interactions

No annotated interactions

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