TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) (Homo sapiens)

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Pyruvate Dehydrogenase ComplexPyruvateIsocitrateFHCSDLATSuccinoyl-CoAACO1Fumarate2-Hydroxy-ethyl-ThPPSuccinateACLYSDHAPDHA1Phosphoenol-pyruvateOGDHMDH1OGDHGlycolysis(S)-MalateDLDSUCLG2ThPPOxaloacetateS-Succinyl-dihydrolipoamide-ECitrateIDH1Lipoamide-EDihydro-lipoamide-EAcetyl-CoAPCBOxalosuccinatePCK1DLSTIDH13-carboxy-1-hydroxypropyl-ThPPIDH3A2-Oxo-glutarateS-Acetyldihydro-lipoamide-EPDHA1ThPPDihydro-lipoamide-ELipoamide-EDLD


Description

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
123103view08:58, 3 July 2022EgonwMade a pathway clickable
117835view15:11, 22 May 2021EweitzModified title
107130view14:21, 17 September 2019MaintBotChEBI identifier normalization
105833view23:08, 15 August 2019KhanspersModified description
96056view16:30, 15 February 2018Mkutmonremoved old pathway attributes
96055view16:28, 15 February 2018MkutmonModified description
96054view16:28, 15 February 2018MkutmonModified description
94220view22:19, 25 August 2017DeSlAdded IDs for 3 missing metabolites
87731view09:25, 25 July 2016MirellaKalafatiOntology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87724view09:20, 25 July 2016MirellaKalafatiOntology Term : 'PW:0000002' removed !
87723view09:19, 25 July 2016MirellaKalafatiOntology Term : 'disease pathway' added !
87722view09:19, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87721view09:19, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
87720view09:18, 25 July 2016MirellaKalafatiModified title
87376view09:56, 22 July 2016MaintBotadded missing graphids
80143view17:16, 14 May 2015Khanspersupdated xrefs
80142view17:11, 14 May 2015Khanspersfixed connections, updated annotations
78495view10:28, 7 January 2015MaintBotadded missing graphIds
72092view21:32, 24 October 2013Mkutmonadded datasource for "Lipoamide-E"
71271view22:16, 16 October 2013MaintBotAutomated update of data sources
69020view17:49, 8 July 2013MaintBotUpdated to 2013 gpml schema
58689view18:30, 19 February 2013MaintBotModified categories
58688view18:29, 19 February 2013MaintBotModified title
58472view20:36, 13 February 2013Maguirre1FINAL v1.0
58471view20:31, 13 February 2013Maguirre1Periodical save, work in progress
58470view20:20, 13 February 2013Maguirre1Periodical save, work in progress
58469view20:10, 13 February 2013Maguirre1Periodical save, work in progress
58468view20:00, 13 February 2013Maguirre1Periodical save, work in progress
58467view19:50, 13 February 2013Maguirre1Periodical save, work in progress
58466view19:40, 13 February 2013Maguirre1Periodical save, work in progress
58465view19:30, 13 February 2013Maguirre1Periodical save, work in progress
58464view19:20, 13 February 2013Maguirre1Periodical save, work in progress
58463view19:10, 13 February 2013Maguirre1Periodical save, work in progress
58461view19:00, 13 February 2013Maguirre1Periodical save, work in progress
58460view18:49, 13 February 2013Maguirre1New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(S)-MalateMetaboliteC00149 (KEGG Compound)
2-Hydroxy-ethyl- ThPPMetaboliteC05125 (KEGG Compound)
2-Oxo-glutarateMetaboliteC00026 (KEGG Compound)
3-carboxy-1- hydroxypropyl-ThPPMetabolite
ACLYGeneProductENSG00000131473 (Ensembl)
ACO1GeneProductENSG00000122729 (Ensembl)
Acetyl-CoAMetaboliteC00024 (KEGG Compound)
CSGeneProductENSG00000062485 (Ensembl)
CitrateMetaboliteC00158 (KEGG Compound)
DLATGeneProductENSG00000150768 (Ensembl)
DLDGeneProductENSG00000091140 (Ensembl)
DLSTGeneProductENSG00000119689 (Ensembl)
Dihydro- lipoamide-EMetabolite
FHGeneProductENSG00000091483 (Ensembl)
FumarateMetaboliteC00122 (KEGG Compound)
GlycolysisPathwayWP534 (WikiPathways)
IDH1GeneProductENSG00000138413 (Ensembl)
IDH3AGeneProductENSG00000166411 (Ensembl)
IsocitrateMetaboliteC00311 (KEGG Compound)
Lipoamide-EMetaboliteC15972 (KEGG Compound)
MDH1GeneProductENSG00000014641 (Ensembl)
OGDHGeneProductENSG00000105953 (Ensembl)
OxaloacetateMetaboliteC00036 (KEGG Compound)
OxalosuccinateMetaboliteC05379 (KEGG Compound)
PCBGeneProduct
PCK1GeneProductENSG00000124253 (Ensembl)
PDHA1GeneProductENSG00000131828 (Ensembl)
Phosphoenol- pyruvateMetaboliteC00074 (KEGG Compound)
PyruvateMetaboliteC00022 (KEGG Compound)
S-Acetyldihydro- lipoamide-EMetaboliteC16255 (KEGG Compound)
S-Succinyl- dihydrolipoamide-EMetabolite
SDHAGeneProductENSG00000073578 (Ensembl)
SUCLG2GeneProductENSG00000172340 (Ensembl)
SuccinateMetaboliteC00042 (KEGG Compound)
Succinoyl-CoAMetaboliteC00091 (KEGG Compound)
ThPPMetaboliteC00068 (KEGG Compound)

Annotated Interactions

No annotated interactions

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