Hepatocyte growth factor receptor signaling (Canis familiaris)
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P
Trancription
Transcription
AP-1
CDC42
pathway
Anoikis
RHO
pathway
RAC1
pathway
Cytoplasm
Changes in Cytoskeleton
and Cell mobility
Actin
Transcription
of Cox2
AKT Pathway
P
Extracellular
Right Click for Comments
P
RAPGEF1
MAP2K2
PIK3CA
RASA1
HGF
PTK2B
ELK1
PXN
MAPK1
PTK2B
SOS1
FOS
PTEN
PAK1
RAF1
ITGB1
Met
HRAS
JUN
PXN
PTK2
PTPN11
STAT3
SRC
SRC
MAPK3
GAB1
RAP1A
MAP4K1
CRK
CRKL
MAP2K1
ITGA1
RAP1B
MAPK8
DOCK1
PTK2
GRB2
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(r21339)
with a 92% conversion rate.
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
118743
view
10:55, 1 June 2021
DeSl
Ontology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
118742
view
10:55, 1 June 2021
DeSl
Ontology Term : 'hepatocyte' added !
118741
view
10:54, 1 June 2021
DeSl
Converted "P" to states
118740
view
10:53, 1 June 2021
DeSl
Converted unconnected lines to Graphical Lines
118739
view
10:53, 1 June 2021
DeSl
Removed textlabel
118737
view
10:52, 1 June 2021
DeSl
Converted ReceptorSquare to MIM binding with lit ref
118736
view
10:51, 1 June 2021
DeSl
Added description from WP313
118036
view
11:49, 23 May 2021
Eweitz
Modified title
87666
view
08:55, 25 July 2016
Lindarieswijk
Ontology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
68535
view
22:20, 5 July 2013
MaintBot
Updated to 2013 gpml schema
40691
view
21:50, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33976
view
18:30, 9 December 2009
MaintBot
Automatic update of empty xrefs
32255
view
12:57, 15 August 2009
MaintBot
Fixed text labels
31776
view
12:10, 14 August 2009
MaintBot
Fixed group labels
31280
view
20:02, 13 August 2009
MaintBot
Fixed text labels
30731
view
22:59, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CRK
GeneProduct
CRKL
GeneProduct
608125 (Entrez Gene)
DOCK1
GeneProduct
486934 (Entrez Gene)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
ELK1
GeneProduct
491860 (Entrez Gene)
FOS
GeneProduct
490792 (Entrez Gene)
GAB1
GeneProduct
483808 (Entrez Gene)
GRB2
GeneProduct
483312 (Entrez Gene)
HGF
GeneProduct
403441 (Entrez Gene)
HRAS
GeneProduct
ITGA1
GeneProduct
489210 (Entrez Gene)
ITGB1
GeneProduct
477956 (Entrez Gene)
JUN
GeneProduct
609429 (Entrez Gene)
MAP2K1
GeneProduct
478347 (Entrez Gene)
MAP2K2
GeneProduct
611939 (Entrez Gene)
MAP4K1
GeneProduct
484527 (Entrez Gene)
MAPK1
GeneProduct
477575 (Entrez Gene)
MAPK3
GeneProduct
486758 (Entrez Gene)
MAPK8
GeneProduct
477746 (Entrez Gene)
Met
GeneProduct
403438 (Entrez Gene)
PAK1
GeneProduct
607885 (Entrez Gene)
PIK3CA
GeneProduct
488084 (Entrez Gene)
PTEN
GeneProduct
403832 (Entrez Gene)
PTK2
GeneProduct
475108 (Entrez Gene)
PTK2B
GeneProduct
486102 (Entrez Gene)
PTPN11
GeneProduct
477488 (Entrez Gene)
PXN
GeneProduct
486299 (Entrez Gene)
RAF1
GeneProduct
484648 (Entrez Gene)
RAP1A
GeneProduct
483225 (Entrez Gene)
RAP1B
GeneProduct
608981 (Entrez Gene)
RAPGEF1
GeneProduct
491286 (Entrez Gene)
RASA1
GeneProduct
479158 (Entrez Gene)
SOS1
GeneProduct
483042 (Entrez Gene)
Son of sevenless homolog 1 (Drosophila) (predicted)
SRC
GeneProduct
485864 (Entrez Gene)
STAT3
GeneProduct
490967 (Entrez Gene)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions