Pentose phosphate pathway (Rattus norvegicus)

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+++NucleotideBiosynthesis6-Phosphonoglucono-delta-lactoneGlucose-6-PhosphatePglsXylulose-5-PhosphateSedoheptulose-7-PhosphateG6pdErythrose-4-PhosphateGlyceraldehyde-3-phosphateTktRpePgdTaldo1Ribulose-5-Phosphate6-PhosphogluconateGlycolysis / GluconeogenesisFructose-6-PhosphateRpiaRibose-5-PhosphateGlyceraldehyde-3-phosphateFructose-6-PhosphateTktGlycolysis / Gluconeogenesis


Description

Pentose phosphate, phosphogluconate, or hexose monophsphate pathway oxidizes glucose-6-phosphate to fructose-6-phosphate and glyceraldehyde-3-P. NADP+ is the electron acceptor. The pathways yields NADPH as well as 5, 4, and 7 carbon intermediaries for synthesis of nucleotides.

Comments

GenMAPP notes 
D. Voet & J.G. Voet (1990) Biochemistry, John Wiley & Sons, New York, pp. 577-583.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP134(r30180) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. D. Voet & J.G. Voet; ''Biochemistry''; John Wiley and sons, 1990

History

View all...
CompareRevisionActionTimeUserComment
125289view17:01, 31 January 2023LarsgwAdd ISBN to reference
116997view10:56, 16 May 2021EweitzModified title
113975view06:40, 14 December 2020EgonwThree more clickable pathways
106974view13:43, 17 September 2019MaintBotHMDB identifier normalization
94902view20:58, 12 October 2017Khanspersremoved GenMAPP notes
94901view20:58, 12 October 2017Khanspersadded lit ref
94900view20:55, 12 October 2017Khanspersconnected final unconnected interactions
94897view13:53, 12 October 2017DeSlConnected lines, changed line type, annotated pathway nodes, changed ribose-5-phosphate to D-ribose...
90523view18:15, 21 November 2016AgustinGVSpecify description
90522view18:08, 21 November 2016AgustinGV
90521view18:02, 21 November 2016AgustinGV
90520view17:46, 21 November 2016AgustinGVModified description
90519view17:37, 21 November 2016AgustinGVUpdate Style. Correct lines
90518view17:33, 21 November 2016AgustinGVPeriodical save, work in progress
90517view17:23, 21 November 2016AgustinGVUpdate Id
88170view08:51, 29 July 2016Mkutmonunconnected line
69328view18:50, 8 July 2013MaintBotUpdated to 2013 gpml schema
67580view11:29, 26 June 2013DdiglesOntology Term : 'pentose phosphate pathway' added !
41639view02:33, 2 March 2011MaintBotRemoved redundant pathway information and comments
34042view18:59, 9 December 2009MaintBotAutomatic update of empty xrefs
32384view16:57, 15 August 2009MaintBotFixed text labels
32027view13:25, 14 August 2009MaintBotFixed group labels
31421view20:58, 13 August 2009MaintBotFixed text labels
30972view00:50, 30 July 2009MaintBotConverted from Homo sapiens
21273view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Pentose Phosphate Pathway]] moved to [[Pathway:WP282]]: Moved to stable identifier
8334view13:46, 7 January 2008MaintBot[[Pathway:Rat:Pentose Phosphate Pathway]] moved to [[Pathway:Rattus norvegicus:Pentose Phosphate Pathway]]: Renaming species
7785view16:17, 18 December 2007MaintBotfixed category names
7391view12:42, 4 November 2007MaintBotAdded categories to GPML
19535view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Pentose_Phosphate_Pathway]]
6585view22:20, 22 May 2007Kdahlquistgpml file for [[Rat:Pentose_Phosphate_Pathway]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
6-PhosphogluconateMetaboliteHMDB01316 (HMDB)
6-Phosphonoglucono-delta-lactoneMetaboliteHMDB01127 (HMDB)
Erythrose-4-PhosphateMetaboliteHMDB01321 (HMDB)
Fructose-6-PhosphateMetabolite643-13-0 (CAS)
Fructose-6-PhosphateMetaboliteHMDB00124 (HMDB)
G6pdGeneProduct24377 (Entrez Gene)
Glucose-6-PhosphateMetabolite59-56-3 (CAS)
Glyceraldehyde-3-phosphateMetaboliteHMDB01112 (HMDB)
Glycolysis / GluconeogenesisPathway
Nucleotide BiosynthesisPathway
PgdGeneProduct100360180 (Entrez Gene)
PglsGeneProduct290636 (Entrez Gene)
Ribose-5-PhosphateMetabolite3615-55-2 (CAS)
Ribulose-5-PhosphateMetabolite4151-19-3 (CAS)
RpeGeneProduct501157 (Entrez Gene)
RpiaGeneProduct362383 (Entrez Gene)
Sedoheptulose-7-PhosphateMetabolite2646-35-7 (CAS)
Taldo1GeneProduct83688 (Entrez Gene)
TktGeneProduct64524 (Entrez Gene)
Xylulose-5-PhosphateMetabolite60802-29-1 (CAS)

Annotated Interactions

No annotated interactions
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