Phase I biotransformations, non-P450 (Equus caballus)

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1HydrolysisOHOHOHOHcarboxylic acid estersESDamidesamidesLIPAPON1Phosphoric acid estersCES1thio estersthio estersPON2CES2Phosphoric acid esterscarboxylic acid estersCES5APON3


Description

This pathway lists several phase 1 biotransformations and their related enzymes.

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP136 (r95126) with a 100.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Klaassen, C.D., Watkins III, J.B.; ''Casarett & Doull's Essentials of Toxicology''; , 2003

History

View all...
CompareRevisionActionTimeUserComment
128193view00:35, 29 January 2024EweitzModified title
125265view12:56, 31 January 2023LarsgwAdd ISBN to publication
107102view14:18, 17 September 2019MaintBotChEBI identifier normalization
95740view13:30, 19 January 2018Mkutmonupdated homology conversion
88306view15:28, 1 August 2016FehrhartOntology Term : 'cytochrome P450-independent phase I biotransformation pathway' added !
73514view23:19, 29 January 2014KhanspersModified title
68737view22:49, 6 July 2013MaintBotUpdated to 2013 gpml schema
58870view00:33, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
40909view22:41, 1 March 2011MaintBotRemoved redundant pathway information and comments
31822view12:24, 14 August 2009MaintBotFixed group labels
30782view23:32, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CES1GeneProductENSECAG00000015451 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000198848
CES2GeneProductENSECAG00000012061 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000172831
CES5AGeneProductENSECAG00000010588 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000159398
ESDGeneProductENSECAG00000024350 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000139684
LIPAGeneProductENSECAG00000010840 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000107798
PON1GeneProductENSECAG00000000344 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000005421
PON2GeneProductENSECAG00000010414 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000105854
PON3GeneProductENSECAG00000009974 (Ensembl) Homology Mapping from Homo sapiens to Equus caballus: Original ID = En:ENSG00000105852
Phosphoric acid estersMetaboliteCHEBI:37734 (ChEBI)
amidesMetabolite32988 (ChEBI)
carboxylic acid estersMetaboliteCHEBI:33308 (ChEBI)
thio estersMetaboliteCHEBI:51277 (ChEBI)

Annotated Interactions

No annotated interactions
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