Platelet-mediated interactions with vascular and circulating cells (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Endothelial cellPlateletMonocyteDendritic cellEosinophilCD40LGNeutrophilPSGL1PSGL1Increased endothelialpermeabilityActivation, differentiationIgG productionInflammatory SignalsInfectionGranule contentreleaseDengue, flu, CMVRecruitment of leukocytesDCs become antigen presenting cellsFormation of Heterotypic Aggregates (HAGs)P-selectinIL1BSELEVCAM1ICAM1TLR2TLR4CD40TLR7CD40PF4SerotoninCCL5TGFB1TGFB2TGFB3B cellT cellNK cellEndothelial cellPSGL1P-selectinCD40-LTLR4IL1BCCL2Name: Platelet-mediated interactions with vascular and circulating cellsOrganism: Homo sapiens


Description

draft

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Quality Tags

Ontology Terms

 

Bibliography

  1. Koupenova M, Clancy L, Corkrey HA, Freedman JE; ''Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis.''; Circ Res, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
139061view05:01, 17 May 2025Khansperscell size
137761view18:46, 7 March 2025KhanspersModified description
134790view02:34, 27 July 2024EweitzMitigate graphical discrepancy between PathVisio and Kaavio / Pvjs
134789view01:34, 27 July 2024EweitzStandardize case, tailor node widths
134788view01:02, 27 July 2024EweitzOntology Term : 'B cell' added !
134787view01:02, 27 July 2024EweitzOntology Term : 'T cell' added !
134786view01:02, 27 July 2024EweitzOntology Term : 'natural killer cell' added !
134785view01:01, 27 July 2024EweitzOntology Term : 'professional antigen presenting cell' added !
134784view01:01, 27 July 2024EweitzOntology Term : 'endothelial cell' added !
134783view01:00, 27 July 2024EweitzOntology Term : 'leukocyte' added !
134782view01:00, 27 July 2024EweitzOntology Term : 'dendritic cell' added !
134781view01:00, 27 July 2024EweitzOntology Term : 'monocyte' added !
134780view00:59, 27 July 2024EweitzOntology Term : 'eosinophil' added !
134779view00:59, 27 July 2024EweitzOntology Term : 'neutrophil' added !
102079view19:26, 28 November 2018EgonwReplaced old Uniprot data sources with the new ones.
102059view21:41, 27 November 2018KhanspersModified description
102058view21:26, 27 November 2018Khanspersfinalized endothelial cell
102047view23:34, 26 November 2018Khanspersmoved PSGL1 to endothelial cell
102046view22:54, 26 November 2018Khanspersupdates based on feedback from original author
101971view14:01, 21 November 2018DeSlChanged secondary to primary ChEBI ID for serotonin.
101846view00:18, 13 November 2018KhanspersOntology Term : 'hemostasis pathway' added !
101845view00:18, 13 November 2018KhanspersOntology Term : 'platelet' added !
101844view00:18, 13 November 2018KhanspersOntology Term : 'thrombosis' added !
101843view00:17, 13 November 2018KhanspersNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
CCL2GeneProductENSG00000108691 (Ensembl)
CCL5GeneProductENSG00000271503 (Ensembl)
CD40-LProteinP29965 (Uniprot-TrEMBL)
CD40GeneProductENSG00000101017 (Ensembl)
CD40LGGeneProductENSG00000102245 (Ensembl)
CD40ProteinP25942 (Uniprot-TrEMBL)
ICAM1GeneProductENSG00000090339 (Ensembl)
IL1BGeneProductENSG00000125538 (Ensembl)
P-selectinProteinP16109 (Uniprot-TrEMBL)
PF4GeneProductENSG00000163737 (Ensembl)
PSGL1ProteinQ14242 (Uniprot-SwissProt)
SELEGeneProductENSG00000007908 (Ensembl)
SerotoninMetaboliteCHEBI:28790 (ChEBI)
TGFB1GeneProductENSG00000105329 (Ensembl)
TGFB2GeneProductENSG00000092969 (Ensembl)
TGFB3GeneProductENSG00000119699 (Ensembl)
TLR2ProteinO60603 (Uniprot-TrEMBL)
TLR4ProteinO00206 (Uniprot-TrEMBL)
TLR7ProteinB2R9N9 (Uniprot-TrEMBL)
VCAM1GeneProductENSG00000162692 (Ensembl)

Annotated Interactions

No annotated interactions

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