Role of carnosine in muscle contraction (Homo sapiens)

Revision as of 15:41, 20 December 2018 by DeSl (Talk | contribs)

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Boldyrev AA, Severin SE; ''The histidine-containing dipeptides, carnosine and anserine: distribution, properties and biological significance.''; Adv Enzyme Regul, 1990 PubMed Europe PMC Scholia
Begum G, Cunliffe A, Leveritt M; ''Physiological role of carnosine in contracting muscle.''; Int J Sport Nutr Exerc Metab, 2005 PubMed Europe PMC Scholia
J.J. O'Dowd, D.J. Robins, D.J. Miller; ''Detection, characterization and quantification of carnosine and other histidyl derivatives in cardiac and skeletal muscle''; https://doi.org/10.1016/0304-4165(88)90015-3, 1988 DOI Scholia
Dobrynina OV, Gorbunova AV; ''[Intensity of biosynthesis of anserine and carnosine by intact and denervated muscles in chickens].''; Biokhimiia, 1968 PubMed Europe PMC Scholia
JF Lenney; ''Carnosinase and homocarnosinosis''; J. Oslo City Hospitals, 35, pp. 27-40, 1985 PubMed Europe PMC Scholia
Ferraris RP, Diamond J, Kwan WW; ''Dietary regulation of intestinal transport of the dipeptide carnosine.''; Am J Physiol, 1988 PubMed Europe PMC Scholia
Nagai K, Suda T; ''Realization of spontaneous healing function by carnosine.''; Methods Find Exp Clin Pharmacol, 1988 PubMed Europe PMC Scholia
Pegova A, Abe H, Boldyrev A; ''Hydrolysis of carnosine and related compounds by mammalian carnosinases.''; Comp Biochem Physiol B Biochem Mol Biol, 2000 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
119317	view	13:22, 23 June 2021	Finterly	Added DOI and PMID for Biopax
116500	view	10:36, 7 May 2021	Eweitz	Modified title
115684	view	19:20, 3 March 2021	AlexanderPico	Modified title
103721	view	15:59, 29 March 2019	DeSl	Modified title
103134	view	19:36, 14 February 2019	Khanspers	Modified description
102351	view	18:27, 20 December 2018	Egonw	Fixed the data source.
102347	view	15:49, 20 December 2018	DeSl	Added last ID for carnosine
102346	view	15:48, 20 December 2018	DeSl	Ontology Term : 'muscle cell' added !
102345	view	15:47, 20 December 2018	DeSl	Ontology Term : 'histidine degradation pathway' added !
102344	view	15:46, 20 December 2018	DeSl	Modified description
102343	view	15:41, 20 December 2018	DeSl	Added more lit. refs and transport of carnosine
102342	view	15:11, 20 December 2018	DeSl	Annotated nodes, added reference for specific compounds location etc.
102341	view	14:55, 20 December 2018	DeSl	New pathway

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Name	Type	Database reference	Comment
AcetylAnserine	Metabolite		Found in Myocardial tissue
Acetylcarnosine	Metabolite	Q4673297 (Wikidata)	Found in Myocardial tissue
Anserine	Metabolite	Q415335 (Wikidata)
Carcinine	Metabolite	Q27892933 (PubChem-compound)
Carnosinase	Protein		"present in many tissues (kidney, liver, plasma) with the exceptions of skeletal musculature"
Carnosine	Metabolite
Carnosine	Metabolite	Q413822 (Wikidata)
Histidine	Metabolite	Q485277 (Wikidata)
Homoanserine	Metabolite	20849429 (PubChem-compound)
Homocarnosine	Metabolite	Q27158831 (Wikidata)
Ophidine	Metabolite	90658938 (PubChem-compound)	aka beta-alanyl-3-N-methylhistidine
beta-alanine	Metabolite	Q310919 (Wikidata)	"Indispensable component of coenzyme A" "Product of pyrimidine base degradation" "Factor which stimulates collagen synthesis in tissues"
carnosinase	Protein	3.4.13.3 (Enzyme Nomenclature)	Specific enzyme for carnosine breakdown (not specified in literature for which reaction). "This enzyme is present in considerable quantity in many tissues (with the exception of skeletal musculature) and is especially abundant in the kidney, liver and blood plasma "
carnosine synthetase	Protein	6.3.2.11 (Enzyme Nomenclature)
gamma-aminobutyric acid	Metabolite	Q210021 (Wikidata)
histamine	Metabolite	Q61233 (Wikidata)

No annotated interactions