Chicken limb development (Gallus gallus)

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12526424624244Limb bud initiation and outgrowthMesodermEctodermProximal-Distal PatterningLimb/Neck Muscle DevelopmentPharyngeal Arch Muscle PrecursorsTermination of limb bud outgrowthEctodermLateral Plate Mesoderm4TBX4RETINOIC ACIDFGF9FGF8BMPFgfRetinoic AcidHOXA11MyodGREM1Fgf17TBX5MEIS1ShhMyf5PITX1WNT3ATBX1FGF4HOXA13Wnt8cPax3Hox proteinsMyoRFgf8NogginHoxc10FGF10Wnt2bSHHPITX2Shh


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

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  1. Verheyden JM, Sun X; ''An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth.''; Nature, 2008 PubMed Europe PMC Scholia
  2. Cooper KL, Hu JK, ten Berge D, Fernandez-Teran M, Ros MA, Tabin CJ; ''Initiation of proximal-distal patterning in the vertebrate limb by signals and growth.''; Science, 2011 PubMed Europe PMC Scholia
  3. Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG; ''Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.''; Development, 2003 PubMed Europe PMC Scholia
  4. Ericsson R, Knight R, Johanson Z; ''Evolution and development of the vertebrate neck.''; J Anat, 2013 PubMed Europe PMC Scholia
  5. Duboc V, Logan MP; ''Regulation of limb bud initiation and limb-type morphology.''; Dev Dyn, 2011 PubMed Europe PMC Scholia
  6. Bouldin CM, Gritli-Linde A, Ahn S, Harfe BD; ''Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning.''; Proc Natl Acad Sci U S A, 2010 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
117081view14:50, 16 May 2021EweitzModified title
102500view13:06, 30 December 2018DeSlOntology Term : 'signaling pathway pertinent to development' added !
102499view13:05, 30 December 2018DeSlModified description
102498view13:04, 30 December 2018DeSlModified description
102497view12:58, 30 December 2018DeSlAnnotated 2 more nodes (for which I previously couldn't find an ID).
102471view08:32, 24 December 2018EgonwReplaced a secondary ChEBI ID with primary ID.
102456view15:03, 23 December 2018DeSlAnnotated right bottom side.
102455view15:00, 23 December 2018DeSlAnnotated left bottom part
102454view14:53, 23 December 2018DeSlAnnotated right top side
102453view14:49, 23 December 2018DeSlAdded ID for left top side; connected unconnected lines
89172view03:44, 23 August 2016AriuttaOntology Term : 'regulatory pathway' added !
78400view10:25, 7 January 2015MaintBotadded missing graphIds
72933view19:31, 16 December 2013JoshloebsSeparated mesoderm and ectoderm
72921view21:46, 15 December 2013JoshloebsSpecify description
72918view18:33, 15 December 2013JoshloebsSpecify description
72917view18:26, 15 December 2013JoshloebsPeriodical save, work in progress
72916view18:16, 15 December 2013JoshloebsPeriodical save, work in progress
72812view19:36, 9 December 2013JoshloebsSpecify description
72811view19:02, 9 December 2013JoshloebsPeriodical save, work in progress
72810view18:56, 9 December 2013JoshloebsSplit Tbx4 and 5
72809view18:51, 9 December 2013JoshloebsSpecify description
72807view18:10, 9 December 2013JoshloebsPeriodical save, work in progress
72806view18:00, 9 December 2013JoshloebsPeriodical save, work in progress
72804view17:34, 9 December 2013JoshloebsAdded limb bud initiation
72803view17:31, 9 December 2013JoshloebsPeriodical save, work in progress
72802view17:20, 9 December 2013JoshloebsPeriodical save, work in progress
72710view19:45, 2 December 2013JoshloebsSpecify description
72706view19:18, 2 December 2013JoshloebsSpecify description
72705view19:17, 2 December 2013JoshloebsAdded Hoxa13
72704view18:45, 2 December 2013JoshloebsSpecify description
72703view18:41, 2 December 2013JoshloebsAnnotation
72702view18:38, 2 December 2013JoshloebsSpecify description
72701view18:29, 2 December 2013JoshloebsSpecify description
72698view18:17, 2 December 2013JoshloebsSpecify description
72676view03:15, 2 December 2013JoshloebsPeriodical save, work in progress
72675view03:05, 2 December 2013JoshloebsPeriodical save, work in progress
72674view02:55, 2 December 2013JoshloebsPeriodical save, work in progress
72673view02:41, 2 December 2013JoshloebsPeriodical save, work in progress
72672view02:31, 2 December 2013JoshloebsPeriodical save, work in progress
72671view02:21, 2 December 2013JoshloebsPeriodical save, work in progress
72670view02:11, 2 December 2013JoshloebsPeriodical save, work in progress
72669view01:28, 2 December 2013JoshloebsPeriodical save, work in progress
72668view01:18, 2 December 2013JoshloebsPeriodical save, work in progress
72510view18:04, 18 November 2013JoshloebsSpecify description
72509view18:01, 18 November 2013JoshloebsSpecify description
72508view17:45, 18 November 2013Joshloebs
72402view18:33, 13 November 2013JoshloebsNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
BMPGeneProduct
FGF10GeneProductENSGALG00000014872 (Ensembl) Lateral Plate Mesoderm
FGF4GeneProductENSGALG00000007562 (Ensembl)
FGF8GeneProductENSGALG00000007706 (Ensembl) Ectoderm
FGF9GeneProductENSGALG00000025748 (Ensembl)
FgfGeneProduct
Fgf17GeneProduct
Fgf8GeneProductENSGALG00000007706 (Ensembl)
GREM1GeneProductENSGALG00000009724 (Ensembl)
HOXA11GeneProductENSGALG00000040021 (Ensembl)
HOXA13GeneProductENSGALG00000027234 (Ensembl)
Hox proteinsGeneProductLateral Plate Mesoderm
Hoxc10GeneProductENSGALG00000029393 (Ensembl)
MEIS1GeneProductENSGALG00000041626 (Ensembl)
Myf5GeneProductENSGALG00000028091 (Ensembl)
MyoRGeneProduct
MyodGeneProductENSGALG00000006216 (Ensembl)
NogginProteinF1NAM3 (Uniprot-TrEMBL)
PITX1GeneProductENSGALG00000030237 (Ensembl) Hindlimb-specific
PITX2GeneProductENSGALG00000042492 (Ensembl)
Pax3GeneProductENSGALG00000005246 (Ensembl)
RETINOIC ACIDMetaboliteCHEBI:15367 (ChEBI) Lateral Plate Mesoderm
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductENSGALG00000006379 (Ensembl)
ShhGeneProductENSGALG00000006379 (Ensembl)
TBX1GeneProductENSGALG00000041182 (Ensembl)
TBX4GeneProductENSGALG00000005285 (Ensembl) Tbx4 in hindlimb. Lateral Plate Mesoderm
TBX5GeneProductENSGALG00000008253 (Ensembl) Tbx5 in forelimb. Lateral Plate Mesoderm
WNT3AGeneProductENSGALG00000042657 (Ensembl)
Wnt2bGeneProductENSGALG00000029570 (Ensembl)
  • Ectoderm
  • Forelimb
Wnt8cGeneProductENSGALG00000037494 (Ensembl)
  • Ectoderm
  • Hindlimb

Annotated Interactions

No annotated interactions

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