IL10 anti-inflammatory signaling (Homo sapiens)

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+LPS induced pathwayBiliverdinBilirubinP38 pathwayMacrophage cytoplasmMAPK pathwayJAK/STAT inducedgenesCOHemeDNAInflammatory cytokinegenesNucleusTNFIL1AIL10IL10RBBLVRASTAT2STAT1HMOX1IL6IL10RASTAT3JAK1BLVRBHMOX1DNA


Description

IL-10 Anti-inflammatory Signaling Pathway.

Pathway based on Biocarta pathway (M6778).

https://cgap.nci.nih.gov/Pathways/BioCarta/h_il10Pathway

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Quality Tags

Ontology Terms

 

Bibliography

  1. Verma R, Balakrishnan L, Sharma K, Khan AA, Advani J, Gowda H, Tripathy SP, Suar M, Pandey A, Gandotra S, Prasad TS, Shankar S; ''A network map of Interleukin-10 signaling pathway.''; J Cell Commun Signal, 2016 PubMed Europe PMC Scholia
  2. Hutchins AP, Diez D, Miranda-Saavedra D; ''The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges.''; Brief Funct Genomics, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
142054view22:48, 30 November 2025EweitzClear deprecated metadata rendering
136674view13:47, 19 February 2025EweitzRefine cell type and organelle label styles
136673view13:46, 19 February 2025EweitzEconomize layout
136672view13:43, 19 February 2025EweitzEconomize layout
129721view01:33, 22 May 2024EweitzModified title
128412view13:01, 4 February 2024EweitzRefine cell type name, expand uncommon abbreviation, tailor pathway node heights
128411view12:54, 4 February 2024EweitzOntology Term : 'macrophage' added !
125654view15:55, 6 March 2023DeSlOntology Term : 'Interleukin-10 signaling pathway' added !
125652view15:53, 6 March 2023DeSlConnected unconnected line
125634view02:03, 6 March 2023AlexanderPicoModified description
123501view04:58, 29 July 2022EgonwMade a pathway clickable
117759view12:53, 22 May 2021EweitzModified title
102692view15:42, 19 January 2019FehrhartOntology Term : 'signaling pathway' added !
102664view12:53, 16 January 2019LaurentModified description
102649view09:19, 16 January 2019LaurentUpdated literature
102648view09:12, 16 January 2019LaurentAdded metabolite and pathway nodes. Fixed interactions
102621view13:54, 14 January 2019LaurentNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BLVRAGeneProduct644 (Entrez Gene)
BLVRBGeneProduct645 (Entrez Gene)
HMOX1GeneProduct3162 (Entrez Gene)
IL10GeneProduct3586 (Entrez Gene)
IL10RAGeneProduct3587 (Entrez Gene)
IL10RBGeneProduct3588 (Entrez Gene)
IL1AGeneProduct3552 (Entrez Gene)
IL6GeneProduct3569 (Entrez Gene)
JAK1GeneProduct3716 (Entrez Gene)
STAT1GeneProduct6772 (Entrez Gene)
STAT2GeneProduct6773 (Entrez Gene)
STAT3GeneProduct6774 (Entrez Gene)
TNFGeneProduct7214 (Entrez Gene)

Annotated Interactions

No annotated interactions

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