Sphingolipid metabolism overview (Mus musculus)
From WikiPathways
Description
This pathway is inspired by the Lipidmaps>Sphingolipids pathway [1].
Quality Tags
Ontology Terms
Bibliography
- Merrill AH Jr; ''De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
- Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH Jr, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S; ''''; , PubMed Europe PMC Scholia
- Le Stunff H, Peterson C, Thornton R, Milstien S, Mandala SM, Spiegel S; ''Characterization of murine sphingosine-1-phosphate phosphohydrolase.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
1-Hexadecenal | Metabolite | LMFA06000088 (LIPID MAPS) | |
3-keto-sphinganine | Metabolite | LMSP01020002 (LIPID MAPS) | |
Asah1 | GeneProduct | ||
Cer-1-P | Metabolite | LMSP02050000 (LIPID MAPS) | |
CerS1 | GeneProduct | P27545 (Uniprot-TrEMBL) | |
CerS4 | GeneProduct | 67260 (Entrez Gene) | |
CerS5 | GeneProduct | 67260 (Entrez Gene) | |
CerS6 | GeneProduct | 241447 (Entrez Gene) | |
Ceramide | Metabolite | LMSP02010000 (LIPID MAPS) | |
Cerk | GeneProduct | 223753 (Entrez Gene) | |
Cers2 | GeneProduct | 76893 (Entrez Gene) | |
Cers3 | GeneProduct | Q1A3B0 (Uniprot-TrEMBL) | |
CoA(16:0) | Metabolite | ||
CoA(18:0) | Metabolite | ||
CoA(20:0) | Metabolite | ||
CoA(22:0) | Metabolite | ||
CoA(24:0) | Metabolite | ||
CoA(24:1) | Metabolite | ||
CoA(26:0) | Metabolite | ||
CoA(26:1) | Metabolite | ||
DH-Cer-1-P | Metabolite | LMSP020500A0 (LIPID MAPS) | |
DH-Ceramide | Metabolite | LMSP02020000 (LIPID MAPS) | |
DH-Gal-Cer | Metabolite | ||
DH-Glc-Cer | Metabolite | ||
DH-SM | Metabolite | LMSP030100A0 (LIPID MAPS) | |
Degs1 | GeneProduct | 13244 (Entrez Gene) | |
Degs2 | GeneProduct | 70059 (Entrez Gene) | |
Ethanolamine-phosphate | Metabolite | 1015 (PubChem-compound) | |
Gal-Cer | Metabolite | LMSP0501AC00 (LIPID MAPS) | |
Glc-Cer | Metabolite | LMSP0501AA00 (LIPID MAPS) | |
Hexadecanal | Metabolite | LMFA06000088 (LIPID MAPS) | |
Kdsr | GeneProduct | 70750 (Entrez Gene) | |
Palmitoyl-CoA | Metabolite | LMFA07050360 (LIPID MAPS) | aka CoA(16:0) |
Ppap2a | GeneProduct | 19012 (Entrez Gene) | |
Ppap2b | GeneProduct | 67916 (Entrez Gene) | |
Ppap2c | GeneProduct | 50784 (NCBI Protein) | |
SM | Metabolite | LMSP03010000 (LIPID MAPS) | |
Serine | Metabolite | 5951 (PubChem-compound) | |
Sgms1 | GeneProduct | 208449 (Entrez Gene) | |
Sgms2 | GeneProduct | 74442 (Entrez Gene) | |
Sgpl1 | GeneProduct | 20397 (Entrez Gene) | |
Smpd1 | GeneProduct | 20597 (Entrez Gene) | |
Sphinganine-1-phosphate | Metabolite | LMSP01050002 (LIPID MAPS) | |
Sphinganine | Metabolite | LMSP01020001 (LIPID MAPS) | |
Sphingosine-1-phosphate | Metabolite | LMSP01050001 (LIPID MAPS) | |
Sphingosine | Metabolite | LMSP01010001 (LIPID MAPS) | |
Sphk1 | GeneProduct | 20698 (Entrez Gene) | |
Sphk2 | GeneProduct | 56632 (Entrez Gene) | |
Sptlc1 | GeneProduct | 268656 (Entrez Gene) | |
Sptlc2 | GeneProduct | ||
Ugcg | GeneProduct | 22234 (Entrez Gene) | |
Ugt8a | GeneProduct | 22239 (Entrez Gene) |
Annotated Interactions
No annotated interactions