Pentose phosphate metabolism (Homo sapiens)

From WikiPathways

Revision as of 19:44, 15 August 2019 by Khanspers (Talk | contribs)
Jump to: navigation, search
1Phosphogluconate Pathway++++G6PDSedoheptulose-7-PhosphateFructose-6-PhosphateXylulose-5-PhosphateGlyceraldehyde-3-phosphateNucleotide BiosynthesisHexose Monophosphosphate ShuntD-Ribose-5-Phosphate6-PhosphogluconatePGLSRPEErythrose-4-PhosphateRibulose-5-PhosphateGlucose-6-PhosphateTALDO1RPIATKTGlyceraldehyde-3-phosphate6-Phosphonoglucono-delta-lactonePGDTKTFructose-6-PhosphateGlycolysis/Gluconeogenesis


Description

Pentose phosphate, phosphogluconate, or hexose monophsphate pathway oxidizes glucose-6-phosphate to fructose-6-phosphate and glyceraldehyde-3-P. NADP+ is the electron acceptor. The pathways yields NADPH as well as 5, 4, and 7 carbon intermediaries for synthesis of nucleotides. This pathway is part the CPTAC Assay Portal.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. D. Voet, J.G. Voet; ''Biochemistry''; 0307-4412(90)90145-E, 1990 DOI Scholia

History

View all...
CompareRevisionActionTimeUserComment
135344view20:19, 27 August 2024Khanspersupdate lit ref
135338view18:47, 26 August 2024Khansperstypo
135336view20:47, 23 August 2024Khanspersupdated lit ref
126271view16:19, 19 April 2023EgonwLicense is CCZero
118339view13:21, 27 May 2021Marvin M2correcting isbn
118338view13:15, 27 May 2021Marvin M2added ref link
117816view14:48, 22 May 2021EweitzModified title
114260view13:56, 2 January 2021EgonwTwo more pathways clickable
106687view12:58, 17 September 2019MaintBotHMDB identifier normalization
106545view00:09, 6 September 2019KhanspersModified description
105782view19:44, 15 August 2019KhanspersModified description
102320view08:15, 20 December 2018FehrhartChanged title due to overlap with other pathway
94935view16:25, 15 October 2017Khanspersconnected line
94922view10:59, 13 October 2017DeSlConnected lines, changed complexes for metabolites to groups, changed textlabel to 2 PW nodes
94920view09:28, 13 October 2017DeSlModified description
94659view11:22, 4 October 2017DeSlchanged label of ribose-5-phosphate to D-ribose-5-phosphate
88600view20:02, 11 August 2016Mkutmonfix unconnected lines
82700view18:54, 22 October 2015EgonwFixed the CAS number; the one that was given was for Glu-1-phosphate.
68931view17:34, 8 July 2013MaintBotUpdated to 2013 gpml schema
67579view11:28, 26 June 2013DdiglesOntology Term : 'pentose phosphate pathway' added !
45148view01:20, 7 October 2011AlexanderPico
45147view01:19, 7 October 2011AlexanderPicoadded pub ref
45146view01:18, 7 October 2011AlexanderPicofixed reactions and pathway ref
43479view08:22, 23 June 2011AdrienDefayadd wikiPathways for the database of Glycolysis/Gluconeogenesis
41079view23:20, 1 March 2011MaintBotRemoved redundant pathway information and comments
38860view18:14, 24 September 2010Khanspers
38773view23:47, 23 September 2010KhanspersAdded pathway links
32324view13:26, 15 August 2009MaintBotFixed text labels
31929view12:55, 14 August 2009MaintBotFixed group labels
30180view20:53, 7 July 2009KhanspersAdded metabolite xrefs
20963view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Pentose Phosphate Pathway]] moved to [[Pathway:WP134]]: Moved to stable identifier
14088view11:35, 21 May 2008MartijnVanIerselLinked up, added metabolites
13102view11:15, 17 May 2008MaintBotautomated metabolite conversion
8330view13:46, 7 January 2008MaintBot[[Pathway:Human:Pentose Phosphate Pathway]] moved to [[Pathway:Homo sapiens:Pentose Phosphate Pathway]]: Renaming species
7783view16:17, 18 December 2007MaintBotfixed category names
7389view12:42, 4 November 2007MaintBotAdded categories to GPML
6361view22:18, 22 May 2007Kdahlquistgpml file for [[Human:Pentose_Phosphate_Pathway]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
6-PhosphogluconateMetaboliteHMDB01316 (HMDB)
6-Phosphonoglucono-delta-lactoneMetaboliteHMDB01127 (HMDB)
D-Ribose-5-PhosphateMetabolite3615-55-2 (CAS)
Erythrose-4-PhosphateMetaboliteHMDB01321 (HMDB)
Fructose-6-PhosphateMetabolite643-13-0 (CAS)
Fructose-6-PhosphateMetaboliteHMDB00124 (HMDB)
G6PDGeneProduct2539 (Entrez Gene)
Glucose-6-PhosphateMetabolite56-73-5 (CAS)
Glyceraldehyde-3-phosphateMetaboliteHMDB01112 (HMDB)
Glycolysis/GluconeogenesisPathwayWP534 (WikiPathways)
Hexose Monophosphosphate ShuntPathway
Nucleotide BiosynthesisPathwayWP404 (WikiPathways)
PGDGeneProduct5226 (Entrez Gene)
PGLSGeneProduct25796 (Entrez Gene)
Phosphogluconate PathwayPathway
RPEGeneProduct6120 (Entrez Gene)
RPIAGeneProduct22934 (Entrez Gene)
Ribulose-5-PhosphateMetabolite4151-19-3 (CAS)
Sedoheptulose-7-PhosphateMetabolite2646-35-7 (CAS)
TALDO1GeneProduct6888 (Entrez Gene)
TKTGeneProduct7086 (Entrez Gene)
Xylulose-5-PhosphateMetabolite60802-29-1 (CAS)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP134"
Personal tools