Vanillin and isovanillin metabolism (Rattus norvegicus)

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1Vanilloylglycineisovanillinisovanilloylglycinevanillic acidAO4-methylguaiacolProtocatechuic acid isovanillyl alcohol4-methylcatecholvanillinvanillyl alcoholIsovanillic acidAldehyde dehydrogenasesGuaiacolvanillic acidCatecholCatechol4-methylcatecholProtocatechuic acid


Description

Proposed metabolic pathways of vanillin and isovanillin in rat.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Strand LP, Scheline RR; ''The metabolism of vanillin and isovanillin in the rat.''; Xenobiotica, 1975 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
107729view13:33, 31 October 2019DeSlOntology Term : 'benzoate degradation pathway' added !
107728view13:31, 31 October 2019DeSlOntology Term : 'exogenous pathway' added !
107727view13:28, 31 October 2019DeSlModified description
107726view13:27, 31 October 2019DeSlAdded some enzyme info for isovanillin
107725view13:15, 31 October 2019DeSlAnnotated part of reactions with Rhea IDs (no enzymes for species known).
107724view12:57, 31 October 2019DeSlSmall layout changes.
107723view12:56, 31 October 2019DeSlUpdated PW with correct interactions between compounds
106993view13:45, 17 September 2019MaintBotHMDB identifier normalization
102687view13:25, 19 January 2019EgonwReplaced secondary ChEBI IDs with primary IDs.
102686view08:53, 19 January 2019AndraAdded protocatechuic acids
102683view08:32, 19 January 2019AndraCreated new vanillin metabolism pathway
102682view07:58, 19 January 2019AndraNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
isovanillyl alcoholMetaboliteQ984208 (Wikidata)
4-methylcatecholMetaboliteQ15303189 (Wikidata)
4-methylguaiacolMetaboliteQ403037 (Wikidata) AKA creosol
AOProtein1.2.3.1 (Enzyme Nomenclature) AKA Aldehyde oxidase
Aldehyde dehydrogenasesProtein1.2.1.3 (Enzyme Nomenclature)
CatecholMetaboliteCHEBI:18135 (ChEBI)
GuaiacolMetaboliteQ412403 (Wikidata)
Isovanillic acidMetaboliteCHEBI:63798 (ChEBI)
Protocatechuic acidMetaboliteCHEBI:36062 (ChEBI)
VanilloylglycineMetaboliteHMDB0060026 (HMDB)
isovanillinMetaboliteQ412986 (Wikidata)
isovanilloylglycineMetabolite
vanillic acidMetaboliteQ419672 (Wikidata)
vanillinMetaboliteQ33495 (Wikidata)
vanillyl alcoholMetaboliteQ2510417 (Wikidata)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
GuaiacolCatecholmim-conversion57425 (Rhea)
Protocatechuic acidCatecholmim-conversion22417 (Rhea)
vanillic acidGuaiacolmim-conversion51529 (Rhea)
vanillinvanillic acidmim-conversion58973 (Rhea)
vanillinvanillyl alcoholmim-conversion10038 (Rhea)
vanillyl alcoholvanillinmim-conversion10037 (Rhea)
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