Globo sphingolipid metabolism (Homo sapiens)

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1Forssman AntigenType IV A AntigenPara-Forssman AntigenType IV B AntigenMetaboliteMetaboliteGb4FUT1ST6GAL1ST8SIA1MetaboliteGb3ST6GALNAC1Globo HMetaboliteABOGloboside SynthaseST6GALNAC6SSEA-4ST6GAL2GALNT2ST6GALNAC3FUT2B3GALT5ST6GALNAC4ST3GAL1ST6GALNAC5A3GALT2SSEA-3A4GALTHexosyltransferasesMetaboliteST3GAL2LacCerABOMetaboliteST6GALNAC2Forssman Antigen SynthaseFUT9GCNT1Metabolite


Description

Globosides are a type of sphingolipids where a ceramide is linked to at least two sugars, however not to sialic acid.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Hannun YA, Obeid LM; ''Sphingolipids and their metabolism in physiology and disease.''; Nat Rev Mol Cell Biol, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117733view12:37, 22 May 2021EweitzModified title
115205view20:53, 4 February 2021Khansperscleaned up layout
110180view14:18, 23 April 2020EgonwOntology Term : 'globoside metabolic pathway' added !
108809view15:53, 30 January 2020DeSlRemoved last modified item.
108808view15:51, 30 January 2020DeSlReconnected last proteins.
108806view15:43, 30 January 2020DeSlConnected proteins in correct manner
108805view15:40, 30 January 2020DeSlAdded lit. ref.
108803view15:34, 30 January 2020DeSlModified description
106691view13:00, 17 September 2019MaintBotHMDB identifier normalization
97521view13:54, 24 May 2018DeSlChanged name for GeneNode.
96291view15:47, 7 March 2018Fehrhartfixed connections
94290view13:04, 31 August 2017DeSlI connected the nodes where I could... don't know what to do with the rest of this PW...
87539view02:06, 25 July 2016AlexanderPicoOntology Term : 'classic metabolic pathway' added !
87538view02:06, 25 July 2016AlexanderPicoOntology Term : 'sphingolipid metabolic pathway' added !
83526view16:40, 20 November 2015JmeliusCorrect outdated id
71392view18:43, 17 October 2013MaintBotAutomated update of data sources
69411view19:01, 8 July 2013EgonwReplaced an outdated HMDB identifier with the 3.5 one.
63195view20:52, 8 May 2013MaintBotUpdating gpml version
62368view00:18, 28 April 2013AlexanderPicoRemoved phantom object
62367view00:17, 28 April 2013AlexanderPicoFixed annotations
59222view20:14, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
41234view23:46, 1 March 2011MaintBotRemoved redundant pathway information and comments
34582view22:21, 21 December 2009KhanspersModified categories
33069view20:53, 11 October 2009MaintBotSpecify description
33068view20:52, 11 October 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A3GALT2GeneProductENSG00000128274 (Ensembl)
A4GALTGeneProductENSG00000128274 (Ensembl) 2.4.1.228
ABOGeneProductENSG00000175164 (Ensembl)
B3GALT5GeneProductENSG00000183778 (Ensembl)
FUT1GeneProductENSG00000174951 (Ensembl)
FUT2GeneProductENSG00000176920 (Ensembl) 2.4.1.69
FUT9GeneProductENSG00000172461 (Ensembl) 2.4.1.152
Forssman Antigen SynthaseGeneProductQ8N5D6 (Uniprot-TrEMBL) 2.4.1.88
GALNT2GeneProductENSG00000143641 (Ensembl)
GCNT1GeneProductENSG00000187210 (Ensembl)
Gb3MetaboliteHMDB0004879 (HMDB)
Gb4MetaboliteHMDB0004960 (HMDB)
Globo HMetaboliteHMDB0004963 (HMDB)
Globoside SynthaseProteinO75752 (Uniprot-TrEMBL)
HexosyltransferasesGeneProduct2.4.1.- (Enzyme Nomenclature) 2.4.1.-
LacCerMetaboliteHMDB0006750 (HMDB)
MetaboliteMetabolite
SSEA-3MetaboliteHMDB0004962 (HMDB)
SSEA-4Metabolite
ST3GAL1GeneProductENSG00000008513 (Ensembl)
ST3GAL2GeneProductENSG00000157350 (Ensembl) 2.4.99.4
ST6GAL1GeneProductENSG00000073849 (Ensembl)
ST6GAL2GeneProductENSG00000144057 (Ensembl)
ST6GALNAC1GeneProductENSG00000070526 (Ensembl)
ST6GALNAC2GeneProductENSG00000070731 (Ensembl)
ST6GALNAC3GeneProductENSG00000184005 (Ensembl)
ST6GALNAC4GeneProductENSG00000136840 (Ensembl)
ST6GALNAC5GeneProductENSG00000117069 (Ensembl)
ST6GALNAC6GeneProductENSG00000160408 (Ensembl)
ST8SIA1GeneProductENSG00000111728 (Ensembl) 2.4.99.8

Annotated Interactions

No annotated interactions

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