VEGFA-VEGFR2 signaling (Homo sapiens)

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27STAT3PROCK2PRKD2535327, 102MAPK3Y204T202MAPK1T185Y18758126, 129MAPK1Y187T185155214, 2712301236, 22, 2452544758, 234MAP2K3MAP2K6P24939MAPK9MAPK8Y185T183STAT3PMAPK3T183228MAPK3T202Y20418645, 123, 146, 173MAPK1Y185127PRKCZ128, 238PIK3R2ACACBNCF2MAPK12RAP1B33VEGFR2Y951Y996MeK1041Y1059Y1175Y1214Y105489201188, 214149AP1complexSoluble andcleaved FLT1may sequesterVEGFA fromVEGFR2PKC delta/ZetadependentEpoxyeicosatrienoicacid regioisomersEC proliferation,migration,tube formationand angiogenesisCYCell motilityand tube formationEC Migration andTube FormationABCF233, 11418FADDTCEB3FAF1FASBIN1BMXHDAC1TNFRSF10CHSPA1ASMARCA257DOK1PGAB1PReceptorPROTEINLigandProtein translocation LEGENDMultiple colored edges are introduced to distinguish the connecting nodesPhosphorylated form with/without site & residueEndosomeNucleusMitochondrionCytoplasmPlasma membraneMTEndoplasmic reticulumCYPMNUERENVEGFR2Y1054Y951Y1214Y801Y1059Y117530VEGFA259MAPK14P117, 190117F-actinreorganization117, 162117Stress fibreformationFocal adhesionassembly andcell migration117NCK1PFYNPPAK2P33STAT1PSTAT6P105, 137STAT1PSTAT6P137NUFRS2PCRKPPRKCI1515151533SRCY530Y4192087RAPGEF1186186RAP1AGTP186ITGAVITGB3Y773186BCAR1P17630, 187PLCG1Y783Ub16SHC1187, 213SHC218733, 127PTK2Y861Y576Y397S732Y407168IQGAP1PRAC1GTP133, 207149149Directed Cell migration135, 149, 215ITGB5ITGB1ITGAV1717, 811717222SH2D2A175175223VascularpermeabilityNAADP65TPCN2Ca2+Ca2+Ca2+Ca2+Ca2+Ca2+6565H+H+H+ATPADP656565Endolysosomalcalcium storeMAPKAPK2T33469, 190190190190PLAUPIP2IP3DAG274274274CAPN2138Ca2+Ca2+Ca2+166MYL2S20T19168Endothelial cellcontraction athigh VEGFA levels16851ROCK1P51, 75RHOAGTP35, 50, 51, 75, 119...207RHOCGTP3, 228Endothelial cellProliferationand migration228228MAP2K1S222S218188, 22822820, 163CBL163163163ITPR1274228PRKCBPRKCAS65790RAF1P6, 90, 254SPHK1PHRASGTP1927410PRKD1S738S742S9101551018, 155HDAC5S259S498155HDAC5S259S498PRKCDPRKCEPLA2G4AP66, 22PGI2HSPB1S78S82S1592150NRP1130, 201CAV1Y14878787CDH5106PTPN11106CSK10610610674PTK2BY402132128, 185HSP90AA1464646, 185267MLLT4210210FHL214014038PLCB3S1105S5372626CDC42GTP26WASF1NCF1PPAK1P140152152PTPN988PTPRZ160606060NCLMYH9NCL122122122122109AKT1T308S473109FOXO1S256AKT1T308S47323, 109, 202109FOXO1S256109, 249109106, 109, 250RELANFKBIA268P919163, 91, 165, 26191PLA2G5RPS6KA5P767676136, 154PIK3R1P73154, 202NOS3S1179S1141692, 138, 154NO154LIMK1S323CFL1S392162162150, 162VAV2Y1725050, 100FLNB9898, 20498PFN1Y12944G-actin bindingand actinpolymerization4At cellleadingedge1142, 234ATF2T71T69Promotes endothelial-leukocyte interactions23423458Endothelialcell survival58, 134GRB2P2020, 10046, 238PXNpY9, 128, 20336GJA1S279S368S255S282S262184ClathrinmediatedGap junctioninternalization123GJA1S262S282S368S255S279Stress fibreformation11PTPRJ250, 251250, 251250SHBP129129129129114, 235114, 235114185185ROCK1P185RPS6KB1T41256TXNIPACP1S-glutathionylation56, 131TXN5656, 131ONOO-5656109, 273Cysteineoxidationof VEGFR2and SRCPTPN6216216GRB10P5531, 152PRKAA1T183ROSMitochondrial21531CytosolicROS79Angiogenesis7979, 8549, 121, 246cGMP121, 164Angiogenesis49, 121, 246CREB1P68CAMKK285, 217ACACAP85, 20085, 217PRKAA2215ARHGEF156464RHOJGTP2576464126SHC1S36126, 213PDPK1S241214PIP2PIP3R1CTORMLST8MAPKAP1MTORS2481S2448199199MTORRAPTORMLST8214214214NRDG1T345mTORC2mTORC1142134, 227GSK3BS9202169, 214214AKT1S1T266271271271RPS6S236S235169, 271136RAPTORMTORMLST8mTORC1169ER stress-independentVEGF-UPR machinerymediated pathwayEIF2AK3ERN1PATF6EIF2AS51169169169GeneexpressionATF4169169DNAJB9HERPUD1169AKT1S4731693311CAPN2166EZR138138138TRPC1ITPR1171KL161161Ca2+Ca2+Ca2+Ca2+Ca2+161171Calciumreleasefrom ERPIK3CA210TXNIPVEGFR256PLCG1Y783RAB5ACDH5S665CTNND1S268S252CTNNB1CTNNA1S453MAP2K1S218S222MAP2K2243243VEGFR2Y1214Y1175Ub192Lysosomemediatedpartialproteosomaldegradation230 kDa160 kDaFBXW11192EEA12525SLC8A1Ca2+Ca2+Ca2+Ca2+232Na+Na+232232232232Mostlyclathrindependentinternalization25HGSY334VEGFR2UbY1214Y1175STAM8484GIPC1MYO6236PTPN1151, 236132272NRP1272272ClathrindependentinternalizationNRP1RAB11VEGFR2NRP1174VEGFR2recycling174239SRCY416Y527VAV2Y172RAC1133, 207GTPPAK2PARRB250, 23923950, 207, 239239239239239239CDH5S655CTNND1CTNNB1ARRB2239239239VE CadherinrecyclingEarly endosomes115115115115Regulation ofcell survivalRegulation ofchromatinremodellingRNA elongationby RNA Pol II115115115VCLS346464646, 18546, 185465Regulation ofendothelial cellsproutingCLTC192Involvedin the activationof VEGFR224MAPKAPK5T1822424NRP2MAP3K5S83MAP2K7PMAP2K4T261JUNS63393939AKT1T308S473CAV1Y1487ARF6275ARF6275ANXA1P265265208NFATC2dePNFATC2deP8, 16, 167, 225167NFATC1NFATC144, 86PTGS216EC Migration83RND1838, 237, 253EGR144, 77, 19844, 77, 198SRF44, 77, 198NR4A2NR4A344PPP3CACREB1P686, 228, 16, 167, 225, 237...Ca2+Ca2+Ca2+JAG1DKK1CCL2CXCL8AMOTBMP10237TEAD493, 1242, 82, 23712422554PKC delta/betadependentTEAD412454269EndosomeRegulation of receptor endocytosis and recyclingCYNUCYNUCYNUCYNUCYNUCYNUCYNUCYNUNUCYNFKB1RELANFKB1ICAM1SELE63Promotes endothelial-leukocyte interactions63165Endothelialcell survival105105FOXO4S197FOXO3249FOXO4FOXO3249249CYNUCYNU249Decreasedexpressionby nuclearexport ofFOXO1/3/4Endothelialcell survival249VEGFR2EndosomeRAB4A113RAB4A113ENPMHGSEPS15EPN1OCLNUbS490ITCHGap junctiondisruptionNa+Na+264156, 180, 264264264Tight junctiondisruption264Occludininternalizationand proteosomaldegradationHDAC7S397S194S479FLNBK1147204204YWHAE256HDAC7S397S479S194HDAC9S245S254HDAC4S467S 246CY196, 204, 256NUMEF2CCCND1228196, 204, 25654, 196, 204, 256RCAN2MMP10MMP14Activationof MEF2 by nuclearexport ofHDACsEC proliferation,migration,tube formationand angiogenesis196, 204, 25654MKNK1PMKNK1P254NUCYEIF4EP254ELK1160OCLNS490Ub45, 264PMENITGAVStimulationof tip cellfilopodiaPLAURPLAU141PLAUProActiveMMP224024012, 141, 252ITGAVITGB1PLAURPLAUCell migrationand invasion141PMENClathrinmediatedF3172NR4A1VCAM1BCL2L1CYP2C8SOD2ADAMTS1ACKR3EGR3172HBEGFRCAN1CDKN1BNUR4A1MEF2C172VCAM1172CCL2BCL2CTNNB1VEGFA SIGNALING PATHWAY IN ENDOTHELIAL CELLSCTNNB1Y142230230112, 230Adherensjunctiondisassembly230ATF2T69T71BCL2L158ERGS21510227NOTCH487ETS1AcT38S41177AA6, 22, 245245PTGS2S-nitrosylPTGS2242NOS3242T172PRKG1164121, 164ProteinComplexSmallmoleculesTranscriptional regulation of gene expression (multiple colours)Unique solid edges between receptor and other proteinsDirect protein-protein interactions associated with VEGFR2 phospho-Y1175Direct protein-protein interactions associated with VEGFR2 phospho-Y801Direct protein-protein interactions associated with VEGFR2 phospho-Y1214Direct protein-protein interactions associated with VEGFR2 phospho-Y951Direct protein interactions of VEGFR2 for which a specific VEGFR2 phosphosite involvement isnot reported AND also represents direct protein-protein interactions between other proteinsDirect phosphorylations by VEGFR2 AND also represents otherdirect kinase-substrate phosphorylation eventsGeneric edges between proteinsSolid edges Dashed edgesDirect protein-protein interactions or enzyme-substrate reactionsLeads to, through unknown or not reported intermediatesDirect dephosphorylation of substrates by phosphatasesDirect ubiquitination of substrates by E3 ubiquitin ligasesDirect protein cleavage of substrates by proteasesDirect inhibition of protein activityDissociation of direct protein-protein interactionsLeads to, through unknown ornot reported/studied intermediatesUbiquitinated form with/without site & residueMethylated form with/without site & residueGlutathionilated form with/without site & residuePTMsProtein transport across multiple cell compartmentsPIP2 PtdIns(4,5)P2PIP3 PtdIns(3,4,5)P3DAG DiacylglycerolIP3 Inositol triphosphateROS Reactive oxygen speciesONOO- PeroxynitriteNAADP Nicotinic acid adenine dinucleotide phosphateATP Adenosine triphosphateGTP Guanosine triphosphateADP Adenosine diphosphateNO Nitric OxidecGMP Cyclic GMPAA Arachidonic AcidPGI2 Prostaglandin I2S-nitrosilated formPROTEINmRNASmallmoleculesmRNAPROTEINModifiedformIncreasedexpressionDecreasedexpressionPI3K-AKT-MTOR ModuleP38 MAPKModuleJNKModulePLC-PKCModuleERKModuleNFKBModuleFAKModuleRACModuleSTATModuleRHOAModuleADAMTS121VEGFA-165aFGAMMRN2TNXBIGFBP7GPC1CTGF671111104144183PGF34FGBFGGVEGFA-145aVEGFA-145bVEGFA-111VEGFA-148VEGFA-165aVEGFA-165bVEGFA-121aVEGFA-121bVEGFA-183aVEGFA-183bVEGFA-162VEGFA-206VEGFA-189aVEGFA-189bMultiple VEGFA isoforms178178FLT1Y1213Y794Y1333Y116972, 9718218218218240, 95220RACK16161Direct protein-protein interactions associated with FLT1 phospho -Y794, -Y1169, -Y1213 & -Y1333VEGFAVEGFA-165a25914852BIRC5MDM2P52ADAM952ADAM10201S1PR1201AFDN21046, 21046, 21035, 50, 51, 75, 229SCUBE2195195ENGCDH5241PFGD5118147, 181181LMO2TAL1GATA2LDB2DLL4179GPX1GJA1159270CYCSMAP2K3CHAC1C15ORF39RAB37ADRB2TRAF3IP2DUSP5EPHA2FJX1TMEM170ASDF2L1SLC2A14IER5SLC39A14ZNF555HLXNRARPSLC25A25CCRL2PNPAPOLD1PIK3R1NDRG1FUT1DLL4SIAH2CASC10TRPC32828SLC7A1212212ArginineIntakeBRD4acetylated form103LARP7CREBBPMEF2C103CXCL8BMP2SEMA6DNR4A2ADAMTS9EGR3NR4A1IGFBP3103CYBBNOX4EPHB2SDCBPPromotesendocytosis120ABL114PRCAN1TNFRSF25255PTPN62247ACOT9ACTG1AKAP2ALBALDOAANXA1AP2A1AP2S1ARF4ARMCX1ARPC5LASCC3ATP6V0D1CSRP2CYR61DECR1DHX29DHX36DNAJA1DNAJB4DPM1DSC1EIF3DEIF3FEIF3HEIF4G1EIF4G2GRSF1HBDHMGB1HSP90AA1HSP90AB2PHTRA1HYOU1IDH2INPP5KIQGAP1KANK1KATNAL2LDHALMAN1P4HBPABPC1PBXIP1PDE4DIPPDIA6PFN1PGDPGK1PLOD3PPM1GPPP1CAPPP2CAPRDX2PRDX6PRKRARPL7RPLP2RPS11SARSSETSH3BGRL3SHROOM2SLC25A11SND1SPIRE1SRP54SRPK1SSR3SSR4STIP1ATP6V1E1BSGCACNA2D1CALRCALUCAPZBCCDC124CCT7CDC42BPBCGNL1CLIC1CNPCOPG1CRIP2CSRP1EPB41EPRSEWSR1FAM120AFARSBFGD5FHOD1FLIIFMNL3FN1FSCN1FXR2GAPDHGIGYF2GLUD1LRRC59LRRFIP2LUC7LMICAL2MOV10MYH11MYO1CMYO6NAP1L1NAPANCLNEXNNUMBOCRLP4HA2PRRC2CPSMD11PSMD4PTMAPTPN14QKIRBM39RCN1RPL10ARPL13ARPL18ARPL26RPL27RPL39P5RPL5SYNJ1TAOK2TBCATCEB1TFAMTFCP2TKTTMOD1TMOD3TMSB10TMSB4XTPM3TPP1TRIP4TUBA1CTUBB8TXNDC5UBAP2LUSP10VPS39YWHAEZC3H1577BCAR1interactome(10', 30', 60')


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89246view16:01, 25 August 2016KhanspersReverted to version '06:50, 25 August 2016' by Khanspers
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89242view06:50, 25 August 2016PrslabOntology Term : 'vascular endothelial growth factor signaling pathway' added !
89241view06:38, 25 August 2016PrslabModified title
89240view06:34, 25 August 2016PrslabNew pathway

External references

DataNodes

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INPP5KGeneProduct51763 (Entrez Gene)
IQGAP1GeneProduct8826 (Entrez Gene)
ITCHProtein83737 (Entrez Gene)
ITGAVProtein3685 (Entrez Gene)
ITGB1Protein3688 (Entrez Gene)
ITGB3Protein3690 (Entrez Gene)
ITGB5Protein3693 (Entrez Gene)
ITPR1Protein3748 (Entrez Gene)
JAG1Protein182 (Entrez Gene)
JUNProtein3725 (Entrez Gene)
KANK1GeneProduct23189 (Entrez Gene)
KATNAL2GeneProduct83473 (Entrez Gene)
KLProtein9365 (Entrez Gene)
LARP7Protein51574 (Entrez Gene)
LDB2Protein9079 (Entrez Gene)
LDHAGeneProduct3939 (Entrez Gene)
LIMK1Protein3984 (Entrez Gene)
LMAN1GeneProduct3998 (Entrez Gene)
LMO2Protein405 (Entrez Gene)
LRRC59GeneProduct55379 (Entrez Gene)
LRRFIP2GeneProduct9209 (Entrez Gene)
LUC7LGeneProduct55692 (Entrez Gene)
MAP2K1Protein5604 (Entrez Gene)
MAP2K2Protein5605 (Entrez Gene)
MAP2K3Protein5606 (Entrez Gene)
MAP2K4Protein6416 (Entrez Gene)
MAP2K6Protein5608 (Entrez Gene)
MAP2K7Protein5609 (Entrez Gene)
MAP3K5Protein4217 (Entrez Gene)
MAPK12Protein6300 (Entrez Gene)
MAPK14Protein1432 (Entrez Gene)
MAPK1Protein5594 (Entrez Gene)
MAPK3Protein5595 (Entrez Gene)
MAPK8Protein5599 (Entrez Gene)
MAPK9Protein5601 (Entrez Gene)
MAPKAP1Protein79109 (Entrez Gene)
MAPKAPK2Protein9261 (Entrez Gene)
MAPKAPK5Protein8550 (Entrez Gene)
MDM2Protein4193 (Entrez Gene)
MEF2CProtein4208 (Entrez Gene)
MICAL2GeneProduct9645 (Entrez Gene)
MKNK1Protein8569 (Entrez Gene)
MLLT4Protein4301 (Entrez Gene)
MLST8Protein64223 (Entrez Gene)
MMP10Protein4319 (Entrez Gene)
MMP14Protein4323 (Entrez Gene)
MMP2Protein4313 (Entrez Gene)
MMRN2Protein79812 (Entrez Gene)
MOV10GeneProduct4343 (Entrez Gene)
MTORProtein2475 (Entrez Gene)
MYH11GeneProduct4629 (Entrez Gene)
MYH9Protein4627 (Entrez Gene)
MYL2Protein4633 (Entrez Gene)
MYO1CGeneProduct4641 (Entrez Gene)
MYO6GeneProduct4646 (Entrez Gene)
NAP1L1GeneProduct4673 (Entrez Gene)
NAPAGeneProduct8775 (Entrez Gene)
NCF1Protein653361 (Entrez Gene)
NCF2Protein4688 (Entrez Gene)
NCK1Protein4690 (Entrez Gene)
NCLGeneProduct4691 (Entrez Gene)
NDRG1Protein10397 (Entrez Gene)
NEXNGeneProduct91624 (Entrez Gene)
NFATC1Protein4772 (Entrez Gene)
NFATC2Protein4773 (Entrez Gene)
NFKB1Protein4790 (Entrez Gene)
NFKBIAProtein4792 (Entrez Gene)
NOS3Protein4846 (Entrez Gene)
NOTCH4Protein4855 (Entrez Gene)
NOX4Protein50507 (Entrez Gene)
NR4A1Protein3164 (Entrez Gene)
NR4A2Protein4929 (Entrez Gene)
NR4A3Protein8013 (Entrez Gene)
NRARPProtein441478 (Entrez Gene)
NRDG1Protein10397 (Entrez Gene)
NRP1Protein8821 (Entrez Gene)
NRP2Protein8828 (Entrez Gene)
NUMBGeneProduct8650 (Entrez Gene)
NUR4A1Protein3164 (Entrez Gene)
OCLNProtein100506658 (Entrez Gene)
OCRLGeneProduct4952 (Entrez Gene)
P4HA2GeneProduct8974 (Entrez Gene)
P4HBGeneProduct5034 (Entrez Gene)
PABPC1GeneProduct26986 (Entrez Gene)
PAK1Protein5058 (Entrez Gene)
PAK2Protein5062 (Entrez Gene)
PBXIP1GeneProduct57326 (Entrez Gene)
PDE4DIPGeneProduct9659 (Entrez Gene)
PDIA6GeneProduct10130 (Entrez Gene)
PDPK1Protein5170 (Entrez Gene)
PFN1GeneProduct5216 (Entrez Gene)
PGDGeneProduct5226 (Entrez Gene)
PGFProtein5228 (Entrez Gene)
PGK1GeneProduct5230 (Entrez Gene)
PIK3CAProtein5290 (Entrez Gene)
PIK3R1Protein5295 (Entrez Gene)
PIK3R2Protein5296 (Entrez Gene)
PLA2G4AProtein5321 (Entrez Gene)
PLA2G5Protein5322 (Entrez Gene)
PLAUProtein5328 (Entrez Gene)
PLAURProtein5329 (Entrez Gene)
PLCB3Protein5331 (Entrez Gene)
PLCG1Protein5335 (Entrez Gene)
PLOD3GeneProduct8985 (Entrez Gene)
PNPProtein4860 (Entrez Gene)
PPM1GGeneProduct5496 (Entrez Gene)
PPP1CAGeneProduct5499 (Entrez Gene)
PPP2CAGeneProduct5515 (Entrez Gene)
PPP3CAProtein5530 (Entrez Gene)
PRDX2GeneProduct7001 (Entrez Gene)
PRDX6GeneProduct9588 (Entrez Gene)
PRKAA1Protein5562 (Entrez Gene)
PRKAA2Protein5563 (Entrez Gene)
PRKCAProtein5578 (Entrez Gene)
PRKCBProtein5579 (Entrez Gene)
PRKCDProtein5580 (Entrez Gene)
PRKCEProtein5581 (Entrez Gene)
PRKCIProtein5584 (Entrez Gene)
PRKCZProtein5590 (Entrez Gene)
PRKD1Protein5587 (Entrez Gene)
PRKD2Protein25865 (Entrez Gene)
PRKG1Protein5592 (Entrez Gene)
PRKRAGeneProduct8575 (Entrez Gene)
PRRC2CGeneProduct23215 (Entrez Gene)
PSMD11GeneProduct5717 (Entrez Gene)
PSMD4GeneProduct5710 (Entrez Gene)
PTGS2Protein5743 (Entrez Gene)
PTK2Protein5747 (Entrez Gene)
PTK2BProtein2185 (Entrez Gene)
PTMAGeneProduct5757 (Entrez Gene)
PTPN11Protein5781 (Entrez Gene)
PTPN14GeneProduct5784 (Entrez Gene)
PTPN1Protein5770 (Entrez Gene)
PTPN6Protein5777 (Entrez Gene)
PTPN9Protein5780 (Entrez Gene)
PTPRJProtein5795 (Entrez Gene)
PTPRZ1Protein5803 (Entrez Gene)
PXNProtein5829 (Entrez Gene)
QKIGeneProduct9444 (Entrez Gene)
R1CTOR Protein253260 (Entrez Gene)
RAB11Protein8766 (Entrez Gene)
RAB37Protein326624 (Entrez Gene)
RAB4AProtein5867 (Entrez Gene)
RAB5AProtein5868 (Entrez Gene)
RAC1Protein5879 (Entrez Gene)
RACK1Protein10399 (Entrez Gene)
RAF1Protein5894 (Entrez Gene)
RAP1AProtein5906 (Entrez Gene)
RAP1BProtein5908 (Entrez Gene)
RAPGEF1Protein2889 (Entrez Gene)
RAPTORProtein253260 (Entrez Gene)
RBM39GeneProduct9584 (Entrez Gene)
RCAN1Protein1827 (Entrez Gene)
RCAN2Protein10231 (Entrez Gene)
RCN1GeneProduct5954 (Entrez Gene)
RELAProtein5970 (Entrez Gene)
RHOAProtein387 (Entrez Gene)
RHOCProtein389 (Entrez Gene)
RHOJProtein57381 (Entrez Gene)
RND1Protein27289 (Entrez Gene)
ROCK1Protein6093 (Entrez Gene)
ROCK2Protein9475 (Entrez Gene)
RPL10AGeneProduct4736 (Entrez Gene)
RPL13AGeneProduct23521 (Entrez Gene)
RPL18AGeneProduct6142 (Entrez Gene)
RPL26GeneProduct6154 (Entrez Gene)
RPL27GeneProduct6155 (Entrez Gene)
RPL39P5GeneProduct553117 (Entrez Gene)
RPL5GeneProduct6125 (Entrez Gene)
RPL7GeneProduct6129 (Entrez Gene)
RPLP2GeneProduct6181 (Entrez Gene)
RPS11GeneProduct6205 (Entrez Gene)
RPS6Protein6194 (Entrez Gene)
RPS6KA5Protein9252 (Entrez Gene)
RPS6KB1Protein6198 (Entrez Gene)
S1PR1Protein1901 (Entrez Gene)
SARSGeneProduct6301 (Entrez Gene)
SCUBE2Protein57758 (Entrez Gene)
SDCBPProtein6386 (Entrez Gene)
SDF2L1Protein23753 (Entrez Gene)
SELEProtein6401 (Entrez Gene)
SEMA6DProtein80031 (Entrez Gene)
SETGeneProduct6418 (Entrez Gene)
SH2D2AProtein9047 (Entrez Gene)
SH3BGRL3GeneProduct83442 (Entrez Gene)
SHBProtein6461 (Entrez Gene)
SHC1Protein6464 (Entrez Gene)
SHC2Protein25759 (Entrez Gene)
SHROOM2GeneProduct357 (Entrez Gene)
SIAH2Protein6478 (Entrez Gene)
SLC25A11GeneProduct8402 (Entrez Gene)
SLC25A25Protein114789 (Entrez Gene)
SLC2A14Protein144195 (Entrez Gene)
SLC39A14Protein21356 (Entrez Gene)
SLC7A1Protein6541 (Entrez Gene)
SLC8A1Protein6546 (Entrez Gene)
SMARCA2Protein6595 (Entrez Gene)
SND1GeneProduct27044 (Entrez Gene)
SOD2Protein6648 (Entrez Gene)
SPHK1Protein55872 (Entrez Gene)
SPIRE1GeneProduct56907 (Entrez Gene)
SRCProtein6714 (Entrez Gene)
SRFProtein6722 (Entrez Gene)
SRP54GeneProduct6729 (Entrez Gene)
SRPK1GeneProduct6732 (Entrez Gene)
SSR3GeneProduct6747 (Entrez Gene)
SSR4GeneProduct6748 (Entrez Gene)
STAMProtein8027 (Entrez Gene)
STAT1Protein6772 (Entrez Gene)
STAT3Protein6774 (Entrez Gene)
STAT6Protein6778 (Entrez Gene)
STIP1GeneProduct10963 (Entrez Gene)
SYNJ1GeneProduct8867 (Entrez Gene)
TAL1Protein6886 (Entrez Gene)
TAOK2GeneProduct9344 (Entrez Gene)
TBCAGeneProduct6902 (Entrez Gene)
TCEB1GeneProduct6921 (Entrez Gene)
TCEB3Protein6924 (Entrez Gene)
TEAD4Protein7004 (Entrez Gene)
TFAMGeneProduct7019 (Entrez Gene)
TFCP2GeneProduct7024 (Entrez Gene)
TKTGeneProduct7086 (Entrez Gene)
TMEM170AProtein124491 (Entrez Gene)
TMOD1GeneProduct7111 (Entrez Gene)
TMOD3GeneProduct29766 (Entrez Gene)
TMSB10GeneProduct9168 (Entrez Gene)
TMSB4XGeneProduct7114 (Entrez Gene)
TNFRSF10CProtein8794 (Entrez Gene)
TNFRSF25Protein8718 (Entrez Gene)
TNXBProtein7148 (Entrez Gene)
TPCN2Protein219931 (Entrez Gene)
TPM3GeneProduct7170 (Entrez Gene)
TPP1GeneProduct1200 (Entrez Gene)
TRAF3IP2Protein10758 (Entrez Gene)
TRIP4GeneProduct9325 (Entrez Gene)
TRPC1Protein7220 (Entrez Gene)
TRPC3Protein7222 (Entrez Gene)
TUBA1CGeneProduct84790 (Entrez Gene)
TUBB8GeneProduct347688 (Entrez Gene)
TXNProtein7295 (Entrez Gene)
TXNDC5GeneProduct81567 (Entrez Gene)
TXNIPProtein10628 (Entrez Gene)
UBAP2LGeneProduct9898 (Entrez Gene)
USP10GeneProduct9100 (Entrez Gene)
VAV2Protein7410 (Entrez Gene)
VCAM1Protein5328 (Entrez Gene)
VCLProtein7414 (Entrez Gene)
VEGFAProtein7422 (Entrez Gene)
VEGFR2Protein3791 (Entrez Gene)
VPS39GeneProduct23339 (Entrez Gene)
WASF1Protein8936 (Entrez Gene)
YWHAEGeneProduct7531 (Entrez Gene)
ZC3H15GeneProduct55854 (Entrez Gene)
ZNF555Protein148254 (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3888"
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