Glycosaminoglycan degradation (Homo sapiens)

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Chondroitin sulfate biosynthesisHyaluronanChondroitin sulfateGlcAbetaGUSBGUSBHYAL4(GalNAc)2 (GlcA)1 (LIdoA)1 (S)3GNSHPSE2GALNSGeneProductGeneProduct(GalNAc)2 (GlcA)1 (LIdoA)1 (S)2(GlcA)1 (GlcNAc)1 (S)1GALNSHEXA(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)4Keratan sulfateGNSNAGLU(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)3HYAL4HYAL1(GlcA)2 (GlcNAc)2GeneProduct(GalNAc)2 (GlcA)1 (S)2(GalNAc)1 (GlcA)1 (S)1IDS(GalNAc)2 (GlcA)1 (S)1hyaluronanGLB1HPSE(GlcA)1 (GlcNAc)1Heparan sulfateARSBDermatan sulfateSGSHGUSBIDUA(GlcA)1 (GlcNAc)2(GlcA)2 (GlcNAc)1 (S)1HGSNATHYAL2Chondroitin sulfateHeparan sulfate biosynthesisHYAL4(GlcA)2 (GlcN)1 (GlcNAc)1 (S)3(GlcA)2 (GlcN)1 (GlcNAc)1 (S)2(GlcA)2 (GlcNAc)2 (S)2(GlcA)2 (GlcNAc)1 (S)2(GlcA)1 (GlcNAc)1Keratan sulfate biosynthesis(Gal)2 (GlcNAc)2 (S)3(Gal)2 (GlcNAc)2 (S)2(Gal)1 (GlcNAc)2 (S)2(Gal)1 (GlcNAc)2 (S)1(Gal)1 (GlcNAc)1 (S)1IDUAIDSHEXBHEXAHEXBGlcNAcbetaGlcAbetaGlcNAcGeneProductGUSBGUSBGlcNAcbetaGlcAbetaGalNAcSSDermatan sulfateSSGalNAcbetaIdoAbetaGlcAbetaGalNAcHeparan sulfateSSSIdoAbetaGlcNalphaGlcAbetaGlcNAcalphaGlcAalphaSSKeratan sulfateSSGalbetaGalbetaGlcNAcbetaGalbetaGlcNAcalphaSARSBIDUAIDSHYAL4HYAL4GUSBARSBGNSHPSEGUSBSGSHHPSE2NAGLUNAGLUIDUAIDSGNSGALNSHEXAHEXBGNSHEXAHEXBGLB1GLB1OMIM:252920Mucopolysaccharidosis, Type IIIBOMIM:253200Mucopolysaccharidosis, Type VIOMIM:230500Gm1-Gangliosidosis, Type IOMIM:252900Mucopolysaccharidosis, Type IIIAOMIM:309900Mucopolysaccharidosis, Type IIOMIM:253200Mucopolysaccharidosis, Type VIOMIM:230500Gm1-Gangliosidosis, Type IOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:253000Mucopolysaccharidosis, Type IVAOMIM:252920Mucopolysaccharidosis, Type IIIBOMIM:607014Hurler SyndromeOMIM:253010Mucopolysaccharidosis, Type IVBOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:252940Mucopolysaccharidosis, Type IIIDOMIM:309900Mucopolysaccharidosis, Type IIOMIM:252900Mucopolysaccharidosis, Type IIIAOMIM:253010Mucopolysaccharidosis, Type IVBOMIM:607014Hurler SyndromeOMIM:252940Mucopolysaccharidosis, Type IIIDOMIM:607014Hurler SyndromeOMIM:253000Mucopolysaccharidosis, Type IVAOMIM:607014Hurler SyndromeOMIM:309900Mucopolysaccharidosis, Type IIOMIM:252940Mucopolysaccharidosis, Type IIIDOMIM:253200Mucopolysaccharidosis, Type VIOMIM:252920Mucopolysaccharidosis, Type IIIBOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:230500Gm1-Gangliosidosis, Type IOMIM:252940Mucopolysaccharidosis, Type IIIDOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:253220Mucopolysaccharidosis, Type VIIOMIM:253010Mucopolysaccharidosis, Type IVBOMIM:309900Mucopolysaccharidosis, Type IIOMIM:252940Mucopolysaccharidosis, Type IIIDOMIM:253000Mucopolysaccharidosis, Type IVA


Description

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Quality Tags

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Bibliography

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History

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CompareRevisionActionTimeUserComment
110276view07:07, 2 May 2020EgonwReplaced secondary ChEBI identifiers with a primary identifiers.
109331view23:23, 13 March 2020KhanspersOntology Term : 'classic metabolic pathway' added !
109330view23:22, 13 March 2020KhanspersOntology Term : 'glycosaminoglycan degradation pathway' added !
109128view06:06, 18 February 2020RleeModified description
109127view06:04, 18 February 2020RleeModified description
109124view05:59, 18 February 2020RleeNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(Gal)1 (GlcNAc)1 (S)1MetaboliteG01391 (KEGG Glycan)
(Gal)1 (GlcNAc)2 (S)1MetaboliteG13074 (KEGG Glycan)
(Gal)1 (GlcNAc)2 (S)2MetaboliteG13073 (KEGG Glycan)
(Gal)2 (GlcNAc)2 (S)2MetaboliteG01977 (KEGG Glycan)
(Gal)2 (GlcNAc)2 (S)3MetaboliteG01945 (KEGG Glycan)
(GalNAc)1 (GlcA)1 (S)1MetaboliteG00872 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (LIdoA)1 (S)2MetaboliteG13042 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (LIdoA)1 (S)3MetaboliteG13041 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (S)1MetaboliteG13043 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (S)2MetaboliteG12336 (KEGG Glycan)
(GlcA)1 (GlcNAc)1 (S)1MetaboliteG09660 (KEGG Glycan)
(GlcA)1 (GlcNAc)1MetaboliteG02632 (KEGG Glycan)
(GlcA)1 (GlcNAc)1MetaboliteG10008 (KEGG Glycan)
(GlcA)1 (GlcNAc)2MetaboliteG00711 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)3MetaboliteG13035 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)4MetaboliteG13034 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (S)2MetaboliteG13037 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (S)3MetaboliteG13036 (KEGG Glycan)
(GlcA)2 (GlcNAc)1 (S)1MetaboliteG13040 (KEGG Glycan)
(GlcA)2 (GlcNAc)1 (S)2MetaboliteG13039 (KEGG Glycan)
(GlcA)2 (GlcNAc)2 (S)2MetaboliteG13038 (KEGG Glycan)
(GlcA)2 (GlcNAc)2MetaboliteG00526 (KEGG Glycan)
ARSBGeneProductENSG00000113273 (Ensembl)
Chondroitin sulfateMetaboliteCHEBI:3676 (ChEBI)
Dermatan sulfateMetaboliteCHEBI:4440 (ChEBI)
GALNSGeneProductENSG00000141012 (Ensembl)
GLB1GeneProductENSG00000170266 (Ensembl)
GNSGeneProductENSG00000135677 (Ensembl)
GUSBGeneProductENSG00000169919 (Ensembl)
GeneProductGeneProduct
HEXAGeneProductENSG00000213614 (Ensembl)
HEXBGeneProductENSG00000049860 (Ensembl)
HGSNATGeneProductENSG00000165102 (Ensembl)
HPSE2GeneProductENSG00000172987 (Ensembl)
HPSEGeneProductENSG00000173083 (Ensembl)
HYAL1GeneProductENSG00000114378 (Ensembl)
HYAL2GeneProductENSG00000068001 (Ensembl)
HYAL4GeneProductENSG00000106302 (Ensembl)
Heparan sulfateMetaboliteCHEBI:5661 (ChEBI)
IDSGeneProductENSG00000010404 (Ensembl)
IDUAGeneProductENSG00000127415 (Ensembl)
Keratan sulfateMetaboliteCHEBI:6119 (ChEBI)
NAGLUGeneProductENSG00000108784 (Ensembl)
SGSHGeneProductENSG00000181523 (Ensembl)
hyaluronanMetaboliteCHEBI:132153 (ChEBI)

Annotated Interactions

No annotated interactions

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