Prostaglandin synthesis and regulation (Mus musculus)

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Cell MembranePhospholipidsCytoplasmPG SynthasesInactive MetabolitesprolactinreleaseCortisoneGq signalingpathwayEdnraPtger4Ptgs2Pla2g4aProstaglandin H2Arachidonic acidAnxa4Cyp11a1TXA2Scgb1a1Hsd11b1CortisolAnxa8CortisolPGF2aPtger1Tbxas1Anxa6Hsd11b2Ptger2PGE2CalciumPGF2aEdnrbPtgirEdn1S100a6Ptgs1PrlAnxa1ProgesteroneAnxa2Anxa5CalciumPtger3PtgdsPGI2S100a10Anxa3HpgdPtgdrPtgfrPtgis


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 83% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Gross G, Imamura T, Muglia LJ; ''Gene knockout mice in the study of parturition.''; J Soc Gynecol Investig, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117938view10:44, 23 May 2021EweitzModified title
114013view15:00, 17 December 2020Fehrhartadded reference mentioned in description
114012view14:59, 17 December 2020Fehrhartconnected line
109402view17:28, 16 March 2020L DupuisConverted interactions to graphical lines
106885view13:36, 17 September 2019MaintBotHMDB identifier normalization
69204view18:24, 8 July 2013MaintBotUpdated to 2013 gpml schema
67608view11:32, 26 June 2013DdiglesOntology Term : 'prostaglandin metabolic pathway' added !
41394view00:29, 2 March 2011MaintBotRemoved redundant pathway information and comments
33046view21:44, 7 October 2009MaintBotAdded xrefs
32411view17:05, 15 August 2009MaintBotFixed text labels
32068view13:35, 14 August 2009MaintBotFixed group labels
31443view21:07, 13 August 2009MaintBotFixed text labels
30835view00:02, 30 July 2009MaintBotConverted from Homo sapiens
21465view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:Prostaglandin synthesis regulation]] moved to [[Pathway:WP374]]: Moved to stable identifier
8344view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Prostaglandin synthesis regulation]] moved to [[Pathway:Mus musculus:Prostaglandin synthesis regulation]]: Renaming species
7790view16:17, 18 December 2007MaintBotfixed category names
7393view12:42, 4 November 2007MaintBotAdded categories to GPML
6487view22:19, 22 May 2007Nsalomonisgpml file for [[Mouse:Prostaglandin_synthesis_regulation]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Anxa1GeneProduct16952 (Entrez Gene)
Anxa2GeneProduct12306 (Entrez Gene)
Anxa3GeneProduct11745 (Entrez Gene)
Anxa4GeneProduct11746 (Entrez Gene)
Anxa5GeneProduct11747 (Entrez Gene)
Anxa6GeneProduct11749 (Entrez Gene)
Anxa8GeneProduct11752 (Entrez Gene)
Arachidonic acidMetaboliteHMDB0001043 (HMDB)
CalciumMetaboliteHMDB0000464 (HMDB)
CortisolMetaboliteHMDB0000063 (HMDB)
Cyp11a1GeneProduct13070 (Entrez Gene)
Edn1GeneProduct13614 (Entrez Gene) PMID: 1474344
EdnraGeneProduct13617 (Entrez Gene)
EdnrbGeneProduct13618 (Entrez Gene)
HpgdGeneProduct15446 (Entrez Gene)
Hsd11b1GeneProduct15483 (Entrez Gene)
Hsd11b2GeneProduct15484 (Entrez Gene)
PGE2MetaboliteHMDB0003175 (HMDB)
PGF2aMetaboliteHMDB0001139 (HMDB)
PGI2MetaboliteHMDB0001335 (HMDB)
Pla2g4aGeneProduct18783 (Entrez Gene)
PrlGeneProduct19109 (Entrez Gene)
ProgesteroneMetaboliteHMDB0001830 (HMDB)
Prostaglandin H2MetaboliteHMDB0001381 (HMDB)
PtgdrGeneProduct19214 (Entrez Gene)
PtgdsGeneProduct19215 (Entrez Gene)
Ptger1GeneProduct19216 (Entrez Gene)
Ptger2GeneProduct19217 (Entrez Gene)
Ptger3GeneProduct19218 (Entrez Gene)
Ptger4GeneProduct19219 (Entrez Gene)
PtgfrGeneProduct19220 (Entrez Gene)
PtgirGeneProduct19222 (Entrez Gene)
PtgisGeneProduct19223 (Entrez Gene)
Ptgs1GeneProduct19224 (Entrez Gene)
Ptgs2GeneProduct19225 (Entrez Gene)
S100a10GeneProduct20194 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
S100a6GeneProduct20200 (Entrez Gene)
Scgb1a1GeneProduct22287 (Entrez Gene) PMID: 7615804, PMID: 3292559
TXA2MetaboliteHMDB0001452 (HMDB)
Tbxas1GeneProduct21391 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP374"
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