Host-pathogen interaction of human coronaviruses - apoptosis (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none SARSApoptosomedeath receptorsApoptosisOC43infectionBIDFADDMBAXAKT1CASP9tBIDAPAF1Cytochrome CCASP8FASLGTNFBADBBC3BCL2L11CASP3CASP7BCL2MCL1BCL2L1E7aMAPK11MAPK12MAPK13MAPK14BAXOC43 infectionSARS3ap38SARSSEN3b68a9bSARSName: Host-pathogen interaction of human corona viruses - apoptosisOrganism: Homo sapiens


Description

Apoptosis induction by human corona virus infection.

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Quality Tags

Image:Curated.pngReview changes for Approved
Image:Featured.pngCurrent Highlight
Image:PLoS_OpenAccess.pngOpen Access
Image:MissingXref.pngAnnotate nodes
Image:Wplogo_31.pngCommunity: COVID-19

Ontology Terms

Bibliography

  1. Li H, Zhu H, Xu CJ, Yuan J; ''Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.''; Cell, 1998 PubMed Europe PMC Scholia
  2. Fung TS, Liu DX; ''Human Coronavirus: Host-Pathogen Interaction.''; Annu Rev Microbiol, 2019 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
124634
Approved
COVID
view12:40, 18 November 2022NhungPupdate viral protein shapes
124632view12:33, 18 November 2022NhungPchange viral proteins shapes
116596view19:12, 8 May 2021EweitzModified title
113801view09:33, 25 November 2020NhungPAnnotated protein 8a and updated protein S and N identifiers
111622view18:17, 30 August 2020Egonw
111365view05:33, 3 August 2020EgonwConverted two interacting Label's to DataNode's.
110821view07:59, 10 June 2020FehrhartModified description
110242view17:35, 29 April 2020EgonwReplaced a secondary ChEBI identifiers with a primary identifier.
110205view10:49, 24 April 2020Fehrhartupdated legend and labels
110200view20:39, 23 April 2020EgonwTyped proteins as Type="Protein"
109973view18:18, 8 April 2020AlexanderPicoupdated sars nodes per #covidpathways guidelines
109950view18:21, 7 April 2020MaintBotAdded two more identifiers.
109876view10:08, 3 April 2020Fehrhartadded information about tBID
109849view11:36, 2 April 2020Fehrhartchanged virus protein visualization
109819view14:57, 1 April 2020Fehrhartadded protein ID for M
109818view14:56, 1 April 2020Fehrhartadded some virus protein IDs
109639view19:00, 27 March 2020FehrhartOntology Term : 'apoptotic cell death pathway' added !
109638view18:59, 27 March 2020FehrhartOntology Term : 'disease pathway' added !
109637view18:59, 27 March 2020FehrhartOntology Term : 'viral infectious disease' added !
109636view18:59, 27 March 2020FehrhartOntology Term : 'severe acute respiratory syndrome' added !
109635view18:56, 27 March 2020FehrhartNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
3aGeneProductP59632 (Uniprot-TrEMBL)
3bGeneProductP59633 (Uniprot-TrEMBL)
6GeneProductP59634 (Uniprot-TrEMBL)
7aGeneProductP59635 (Uniprot-TrEMBL)
8aGeneProduct
9bGeneProductP59636 (Uniprot-TrEMBL)
AKT1GeneProduct207 (Entrez Gene)
APAF1GeneProductENSG00000120868 (Ensembl)
BADGeneProductENSG00000002330 (Ensembl)
BAXGeneProductENSG00000087088 (Ensembl)
BBC3GeneProductENSG00000105327 (Ensembl) PUMA
BCL2GeneProductENSG00000171791 (Ensembl)
BCL2L11GeneProductENSG00000153094 (Ensembl) BIM
BCL2L1GeneProductENSG00000171552 (Ensembl)
BIDGeneProductENSG00000015475 (Ensembl)
CASP3GeneProductENSG00000164305 (Ensembl)
CASP7GeneProductENSG00000165806 (Ensembl)
CASP8GeneProductENSG00000064012 (Ensembl)
CASP9GeneProductENSG00000132906 (Ensembl)
Cytochrome CMetaboliteCHEBI:4062 (ChEBI)
EGeneProductP59637 (Uniprot-TrEMBL)
FADDGeneProductENSG00000168040 (Ensembl)
FASLGGeneProductENSG00000117560 (Ensembl)
MGeneProduct
MAPK11GeneProductENSG00000185386 (Ensembl)
MAPK12GeneProductENSG00000188130 (Ensembl)
MAPK13GeneProductENSG00000156711 (Ensembl)
MAPK14GeneProductENSG00000112062 (Ensembl)
MCL1GeneProductENSG00000143384 (Ensembl)
NGeneProduct
SGeneProduct
TNFGeneProductENSG00000232810 (Ensembl)
tBIDGeneProductENSG00000015475 (Ensembl) truncated BID

Annotated Interactions

No annotated interactions

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