Omega-3 / omega-6 fatty acid synthesis (Mus musculus)
From WikiPathways
Description
This pathway is inspired by the Lipidmaps>Omega-3 and omega-6 fatty acids) [1].
Omega-3 and omega-6 FAs (Fatty acids) are important fats obtained from diet, and are both polyunsaturated (indicating many double bonds in the lipid tail).The position of the double bond is given in the name of the lipid, for example 22:2(13Z,16Z) means a tail length of 22 carbons, with 2 double bond. One double bond is at the 13 Carbon, the second on the 16th.This number is counted from the tail end of the lipid chain (indicating that the example lipid is a 22 - 16 = omega-6 FA).
Quality Tags
Ontology Terms
Saving...Bibliography
- Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH Jr, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S; ''A mouse macrophage lipidome.''; J Biol Chem, 2010 PubMed Europe PMC Scholia
History
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External references
DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| 20:2(11Z,14Z) | Metabolite | LMFA07050036 (LIPID MAPS)  | aka 11,14-eicosadienoic acid |
| 20:3(11Z,14Z,17Z) | Metabolite | LMFA01030378 (LIPID MAPS) | AKA 11,14,17-eicosatrienoic acid |
| 20:4(8Z,11Z,14Z,17Z) | Metabolite | LMFA01030818 (LIPID MAPS) | |
| 20:5(5Z,8Z,11Z,14Z,17Z) | Metabolite | LMFA01030759 (LIPID MAPS) | |
| 22:2(13Z,16Z) | Metabolite | LMFA01030405 (LIPID MAPS) | aka 13,16-docodadienoic acid |
| 22:4(7Z,10Z,13Z,16Z) | Metabolite | LMFA01030178 (LIPID MAPS) | |
| 22:5(4Z,7Z,10Z,13Z,16Z) | Metabolite | LMFA04000064 (LIPID MAPS) | |
| 22:5(7Z,10Z,13Z,16Z,19Z) | Metabolite | LMFA04000044 (LIPID MAPS) | |
| 24:4(9Z,12Z,15Z,18Z) | Metabolite | LMFA01030819 (LIPID MAPS) | |
| 24:5(6Z,9Z,12Z,15Z,18Z) | Metabolite | LMFA01030820 (LIPID MAPS) | |
| 24:5(9Z,12Z,15Z,18Z,21Z) | Metabolite | LMFA01030821 (LIPID MAPS) | |
| 24:6(6Z,9Z,12Z,15Z,18Z,21Z) | Metabolite | LMFA01030822 (LIPID MAPS) | |
| Acls3 | GeneProduct | 74205 (Entrez Gene) | |
| Acls4 | GeneProduct | 50790 (Entrez Gene) | |
| Acot1 | GeneProduct | 26897 (Entrez Gene) | |
| Acot2 | GeneProduct | 171210 (Entrez Gene) | |
| Acox1 | GeneProduct | 11430 (Entrez Gene) | |
| Acox3 | GeneProduct | 80911 (Entrez Gene) | |
| Acsl1 | GeneProduct | 14081 (Entrez Gene) | |
| Acsl3 | GeneProduct | 74205 (Entrez Gene) | |
| Acsl4 | GeneProduct | 50790 (Entrez Gene) | |
| Arachidonic acid | Metabolite | LMFA01030001 (LIPID MAPS) | |
| Arachidonoyl-CoA | Metabolite | LMFA07050288 (LIPID MAPS) | aka CoA(20:4) |
| Bishomo-gamma-linolenic acid | Metabolite | LMFA01030158 (LIPID MAPS) | |
| CoA(18:2(9Z,12Z)) | Metabolite | LMFA07050343 (LIPID MAPS) | |
| CoA(18:3(6Z,9Z,12Z)) | Metabolite | LMFA07050322 (LIPID MAPS) | |
| CoA(18:3(9Z,12Z,15Z)) | Metabolite | LMFA07050286 (LIPID MAPS) | |
| CoA(18:4(6Z,9Z,12Z,15Z)) | Metabolite | LMFA07050123 (LIPID MAPS) | |
| CoA(20:2(11Z,14Z)) | Metabolite | LMFA07050036 (LIPID MAPS) | |
| CoA(20:3(11Z,14Z,17Z)) | Metabolite | LMFA07050044 (LIPID MAPS) | |
| CoA(20:3(8Z,11Z,14Z)) | Metabolite | LMFA07050278 (LIPID MAPS) | |
| CoA(20:4(8Z,11Z,14Z,17Z)) | Metabolite | LMFA07050134 (LIPID MAPS) | |
| CoA(20:5) | Metabolite | LMFA07050122 (LIPID MAPS) | |
| CoA(22:2) | Metabolite | LMFA07050037 (LIPID MAPS) | |
| CoA(22:4) | Metabolite | LMFA07050129 (LIPID MAPS) | |
| CoA(22:5(4Z,7Z,10Z,13Z,16Z)) | Metabolite | LMFA07050043 (LIPID MAPS) | |
| CoA(22:5(7Z,10Z,13Z,16Z,19Z)) | Metabolite | LMFA07050131 (LIPID MAPS) | |
| CoA(22:6) | Metabolite | LMFA07050121 (LIPID MAPS) | |
| CoA(24:4) | Metabolite | LMFA07050139 (LIPID MAPS) | |
| CoA(24:5(6Z,9Z,12Z,15Z,18Z)) | Metabolite | LMFA07050042 (LIPID MAPS) | |
| CoA(24:5(9Z,12Z,15Z,18Z,21Z)) | Metabolite | LMFA07050141 (LIPID MAPS) | |
| CoA(24:6) | Metabolite | LMFA07050127 (LIPID MAPS) | |
| DHA | Metabolite | LMFA01030185 (LIPID MAPS) | |
| Elovl2 | GeneProduct | 54326 (Entrez Gene) | |
| Elovl5 | GeneProduct | 68801 (Entrez Gene) | |
| Fads1 | GeneProduct | 76267 (Entrez Gene) | |
| Fads2 | GeneProduct | 56473 (Entrez Gene) | |
| Glycerophospholipids | Metabolite | CHEBI:37739 (ChEBI) | |
| Linoleic acid | Metabolite | LMFA01030120 (LIPID MAPS) | |
| Pla2g4a | Protein | 18783 (Entrez Gene) | |
| Pla2g4b | Protein | 211429 (Entrez Gene) | |
| Pla2g5 | Protein | 18784 (Entrez Gene) | |
| Pla2g6 | Protein | 53357 (Entrez Gene) | |
| Stearidonic acid | Metabolite | LMFA01030357 (LIPID MAPS) | aka 5,8,11,14,17-eicosapentaenoic acid |
| alpha-Linolenic acid | Metabolite | LMFA01030152 (LIPID MAPS) | |
| gamma-Linolenic acid | Metabolite | LMFA01030141 (LIPID MAPS) |
Annotated Interactions
No annotated interactions
