Adverse outcome pathway for mitochondrial complex 1 (C1) inhibition (Homo sapiens)
From WikiPathways
Description
AOP for C1 inhibition
Quality Tags
Ontology Terms
Bibliography
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History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Apoptosis | Pathway | WP1772 (WikiPathways) | |
Autophagy | Pathway | WP4923 (WikiPathways) | |
Decreased mitochondrial oxidative phosphorylation | Pathway | WP111 (WikiPathways) | |
Decreased proximal tubule vectorial transport | Pathway | WP4917 (WikiPathways) | |
Degeneration of DA neurons of nigrostratial pathway | Pathway | WP2855 (WikiPathways) | |
Deguelin | Metabolite | CHEBI:4357 (ChEBI) | |
Ferroptosis | Pathway | WP4313 (WikiPathways) | |
Impaired proteostasis | Pathway | WP4918 (WikiPathways) | |
Increased ROS | Pathway | WP3941 (WikiPathways) | |
Inhibition of mitochondrial Complex I | Pathway | WP4324 (WikiPathways) | |
Necrosis | Pathway | WP3383 (WikiPathways) | |
Neuroinflammation | Pathway | WP4919 (WikiPathways) | |
Parkinsonian motor deficits | Pathway | WP2371 (WikiPathways) | |
Rotenone | Metabolite | CHEBI:28201 (ChEBI) | |
UPR | Pathway | WP4925 (WikiPathways) |
Annotated Interactions
No annotated interactions