Butyrate-induced histone acetylation (Bos taurus)

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21ButyrateAcetylated HistoneTCAcycleCitrateBeta oxidationLipidbiosynthesisAKT1HDACsAcetyl CoACitrateButyrateAcetyl CoAACLYButyrateGlucoseButyrate


Description

Metabolism of butyrate is suggested to be an energy source for histone acetylation.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2366(73980) with a 66.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Davie JR; ''Inhibition of histone deacetylase activity by butyrate.''; J Nutr, 2003 PubMed Europe PMC Scholia
  2. Donohoe DR, Collins LB, Wali A, Bigler R, Sun W, Bultman SJ; ''The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation.''; Mol Cell, 2012 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
115748view11:19, 9 March 2021EgonwReplaced the WP id of a human pathways with the matching cow pathway
102130view21:15, 1 December 2018EgonwReplaced Wikipedia with Wikidata identifiers.
89151view03:06, 23 August 2016AriuttaOntology Term : 'classic metabolic pathway' added !
80881view15:29, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACLYProteinENSBTAG00000016740 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P53396
AKT1ProteinENSBTAG00000017636 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P31749
Acetyl CoAMetaboliteCHEBI:15351 (ChEBI)
Acetylated HistoneComplexQ36293 (Wikidata)
ButyrateMetaboliteCHEBI:17968 (ChEBI)
CitrateMetaboliteCHEBI:35808 (ChEBI)
GlucoseMetaboliteCHEBI:17634 (ChEBI)
HDACsProtein
Lipid biosynthesisPathwayWP1020 (WikiPathways)
TCA cyclePathwayWP78 (WikiPathways)

Annotated Interactions

No annotated interactions
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