Central carbon metabolism (Escherichia coli)

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View approved pathways at the new wikipathways.org.

Haverkorn van Rijsewijk BR, Nanchen A, Nallet S, Kleijn RJ, Sauer U; ''Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli.''; Mol Syst Biol, 2011 PubMed Europe PMC Scholia

Revision	Action	Time	User	Comment
117433	view	10:50, 21 May 2021	Eweitz	Modified title
89169	view	03:42, 23 August 2016	Ariutta	Ontology Term : 'classic metabolic pathway' added !
83523	view	08:34, 20 November 2015	Anwesha	New pathway

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Name	Type	Database reference
2-OG	Metabolite	C00026 (KEGG Compound)
6PG	Metabolite	C00345 (KEGG Compound)
Ace-CoA	Metabolite	C00024 (KEGG Compound)
Ace	Metabolite	C00033 (KEGG Compound)
CIT	Metabolite	C00158 (KEGG Compound)
F6P	Metabolite	C05345 (KEGG Compound)
FBP	Metabolite	C05378 (KEGG Compound)
FUM	Metabolite	C00122 (KEGG Compound)
G6P	Metabolite	C00668 (KEGG Compound)
GOX	Metabolite
Galactose	Metabolite	C00124 (KEGG Compound)
Glucose	Metabolite	C00221 (KEGG Compound)
ICT	Metabolite	C00311 (KEGG Compound)
MAL	Metabolite	C00149 (KEGG Compound)
OAA	Metabolite	C00036 (KEGG Compound)
P5P	Metabolite
PEP	Metabolite	C00074 (KEGG Compound)
PYR	Metabolite	C00022 (KEGG Compound)
SUC-CoA	Metabolite	C00091 (KEGG Compound)
SUC	Metabolite	C00042 (KEGG Compound)
T3P	Metabolite	C00197 (KEGG Compound)

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Source	Target	Type	Database reference	Comment
2-OG	SUC-CoA	Arrow	R01197 (KEGG Reaction)
6PG		Arrow	WpR4 (WikiPathways)
6PG	P5P	Arrow	WpR11 (WikiPathways)
Ace-CoA	Ace	Arrow	R00227 (KEGG Reaction)
Ace-CoA			R00351 (KEGG Reaction)
Ace-CoA			WpR12 (WikiPathways)
		Arrow	WpR13 (WikiPathways)
		Arrow	WpR4 (WikiPathways)
CIT	ICT	Arrow	WpR2 (WikiPathways)	R01325 : Citrate <=> cis-Aconitate + H2O R01900 : Isocitrate <=> cis-Aconitate + H2O
F6P	FBP	Arrow	WpR6 (WikiPathways)
FBP	T3P	Arrow	WpR5 (WikiPathways)
FUM	MAL	Arrow	R01082 (KEGG Reaction)
G6P	6PG	Arrow	WpR3 (WikiPathways)	R02035 : D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate R02736 : beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+
G6P	F6P	Arrow	R03321 (KEGG Reaction)
GOX	MAL	Arrow	WpR12 (WikiPathways)
Galactose	G6P	Arrow	WpR7 (WikiPathways)
Glucose	G6P	Arrow	R01600 (KEGG Reaction)
ICT	2-OG	Arrow	R00709 (KEGG Reaction)
ICT	GOX	Arrow	WpR13 (WikiPathways)
MAL	OAA	Arrow	R00361 (KEGG Reaction)
MAL	PYR	Arrow	WpR9 (WikiPathways)
OAA		Arrow	WpR10 (WikiPathways)
OAA	CIT	Arrow	R00352 (KEGG Reaction)
PEP		Arrow	R00431 (KEGG Reaction)
PEP	PYR	Arrow	WpR8 (WikiPathways)
PYR	Ace-CoA	Arrow	R00209 (KEGG Reaction)
SUC-CoA	SUC	Arrow	R00432 (KEGG Reaction)
SUC	FUM	Arrow	R02164 (KEGG Reaction)
T3P	PEP	Arrow	WpR1 (WikiPathways)	R00658 : 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O R01518 : 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate