Serotonin receptor 4/6/7 and NR3C signaling (Homo sapiens)

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81, 10416, 10340, 822, 5, 35, 39, 47...1, 41688777, 834, 9, 14, 20, 24...12, 38603619, 21, 28, 29, 42...34, 6436, 8017, 9930, 453722587, 33, 49, 61, 78...6, 8, 50, 74, 9862, 973, 23, 31, 46, 51...56, 637910, 22, 25, 65, 72...86, 10213, 43, 67, 69, 71...15, 52, 8489, 905511, 26, 57, 9227, 4453, 70856818, 32, 59, 75, 93ADCYATF1GNASHTR6CREB1NR3C1EGR1MAP2K1RAP1AserotoninMAPK1HTR7BRAFHTR4MAP2K2PKAELK1RPS6KMAPKAPK2RPS6KA5MAPK3SRFCyclic AMPELK4


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This pathway is courtesy of Ariadne Genomics Pathway Studio. Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

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Bibliography

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125660view16:05, 6 March 2023DeSlAdded legend from WP722
125626view01:53, 6 March 2023AlexanderPicoModified description
117826view15:06, 22 May 2021EweitzModified title
106485view21:40, 4 September 2019KhanspersModified description
105811view22:54, 15 August 2019KhanspersModified description
101930view12:33, 18 November 2018EgonwRemoved whitespace in one more PubMed identifier.
101925view17:08, 17 November 2018EgonwRemoved whitespace in PubMed identifiers.
74438view06:47, 20 April 2014EgonwRemoved brackets and text from PubMed IDs, e.g. "10542136 The " changed to "10542136".
70102view18:49, 12 July 2013MaintBotupdated to 2013 schema
49544view10:12, 20 July 2012AndraWp tidy
46089view02:26, 15 December 2011AllanKuchinskyupdated HGNC IDs
45037view18:51, 6 October 2011ThomasOntology Term : 'neuron' added !
45028view18:45, 6 October 2011ThomasOntology Term : 'serotonin signaling pathway' added !
41156view23:41, 1 March 2011MaintBotRemoved redundant pathway information and comments
39769view07:55, 17 January 2011AlexanderPico
34438view18:16, 10 December 2009MaintBotAutomatic update of empty xrefs
33188view18:03, 5 November 2009KhanspersModified categories
31152view04:06, 5 August 2009ArukeModified description
30237view22:53, 16 July 2009ArukeUpdated all interactions and references
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30232view21:32, 16 July 2009ArukePeriodical save, work in progress
30231view21:22, 16 July 2009ArukePeriodical save, work in progress
30230view21:12, 16 July 2009ArukePeriodical save, work in progress
30229view21:01, 16 July 2009ArukePeriodical save, work in progress
30228view20:51, 16 July 2009ArukePeriodical save, work in progress
30227view20:41, 16 July 2009ArukePeriodical save, work in progress
30226view20:31, 16 July 2009ArukePeriodical save, work in progress
30225view17:24, 16 July 2009ArukeUpdated all nodes
30224view17:16, 16 July 2009ArukePeriodical save, work in progress
30223view17:06, 16 July 2009ArukePeriodical save, work in progress
30222view16:55, 16 July 2009ArukeNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADCYGeneProductAdenylate cyclase
ATF1GeneProduct466 (Entrez Gene) activating transcription factor 1
BRAFGeneProduct673 (Entrez Gene) v-raf murine sarcoma viral oncogene homolog B1
CREB1GeneProduct1385 (Entrez Gene) cAMP response element-binding protein 1
Cyclic AMPMetabolite60-92-4 (CAS)
EGR1GeneProduct1958 (Entrez Gene) early growth response protein
ELK1GeneProduct2002 (Entrez Gene) ELK1, member of ETS oncogene family
ELK4GeneProduct2005 (Entrez Gene) ETS domain-containing protein Elk-4 (SRF accessory protein 1)
GNASGeneProduct2778 (Entrez Gene) GNAS (guanine nucleotide binding protein, alpha stimulating)
HTR4GeneProduct3360 (Entrez Gene) 5 hydroxytryptamine (serotonin) receptor 4
HTR6GeneProduct3362 (Entrez Gene) 5-hydroxytryptamine (serotonin) receptor 6
HTR7GeneProduct3363 (Entrez Gene) 5-hydroxytryptamine (serotonin) receptor 7
MAP2K1GeneProduct5604 (Entrez Gene) mitogen activated protein kinase kinase 1
MAP2K2GeneProduct5605 (Entrez Gene) mitogen activated protein kinase kinase 2
MAPK1GeneProductMAPK1 (HGNC) mitogen activated protein kinase 1
MAPK3GeneProduct5595 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK2GeneProduct9261 (Entrez Gene) MAP kinase-activated protein kinase 2
NR3C1GeneProduct2908 (Entrez Gene) nuclear receptor, subfamily 3, group C, member 1
PKAGeneProductcAMP-dependent protein kinase, protein kinase A
RAP1AGeneProduct5906 (Entrez Gene) RAS-related protein-1a
RPS6KGeneProductribosomal protein S6 kinase
RPS6KA5GeneProduct9252 (Entrez Gene) ribosomal protein S6 kinase, polypeptide 5
SRFGeneProduct6722 (Entrez Gene) serum response factor
serotoninMetabolite50-67-9 (CAS)

Annotated Interactions

No annotated interactions

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