Hepatocyte growth factor receptor signaling (Rattus norvegicus)
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DeSl
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Changes in Cytoskeleton
and Cell mobility
AP-1
Trancription
Transcription
of Cox2
Extracellular
Transcription
Cytoplasm
P
Actin
RAC1
pathway
P
CDC42
pathway
Anoikis
AKT Pathway
P
RHO
pathway
Elk1
Sos1
Hgf
Pten
Pxn
Crkl
Crk
Mapk3
Jun
Gab1
Met
Itgb1
Ptk2
Dock1
RAPGEF1
Stat3
Ptpn11
Pak1
Grb2
Raf1
Rap1b
Rasa1
Map4k1
Src
Pxn
Ptk2
Map2k2
Fos
Rap1a
PIK3CA
Src
Map2k1
Hras
Mapk1
Mapk8
Itga1
Ptk2b
Ptk2b
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(r21339)
with a 92% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
118829
view
09:00, 2 June 2021
DeSl
Added description from WP313
118828
view
08:59, 2 June 2021
DeSl
Converted "P" to States
118827
view
08:58, 2 June 2021
DeSl
Converted ReceptorSquare to MIM binding with lit. ref.
118826
view
08:57, 2 June 2021
DeSl
Removed textlabel
118825
view
08:56, 2 June 2021
DeSl
Ontology Term : 'hepatocyte' added !
118824
view
08:56, 2 June 2021
DeSl
Ontology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
117011
view
11:22, 16 May 2021
Eweitz
Modified title
109393
view
16:05, 16 March 2020
L Dupuis
Converted interactions to graphical lines
69363
view
18:54, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67647
view
11:44, 26 June 2013
Ddigles
Ontology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
41677
view
02:35, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34067
view
19:08, 9 December 2009
MaintBot
Automatic update of empty xrefs
33589
view
09:53, 1 December 2009
MaintBot
Removed group label
31612
view
22:15, 13 August 2009
MaintBot
Fixed text labels
30988
view
00:55, 30 July 2009
MaintBot
Converted from Homo sapiens
20879
view
11:30, 14 November 2008
MaintBot
[[Pathway:Rattus norvegicus:Signaling of Hepatocyte Growth Factor Receptor Biocarta]] moved to [[Pathway:WP94]]: Moved to stable identifier
8388
view
13:46, 7 January 2008
MaintBot
[[Pathway:Rat:Signaling of Hepatocyte Growth Factor Receptor Biocarta]] moved to [[Pathway:Rattus norvegicus:Signaling of Hepatocyte Growth Factor Receptor Biocarta]]: Renaming species
7811
view
16:19, 18 December 2007
MaintBot
fixed category names
7297
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6593
view
22:20, 22 May 2007
169.230.77.174
gpml file for [[Rat:Signaling_of_Hepatocyte_Growth_Factor_Receptor_Biocarta]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Crk
GeneProduct
54245 (Entrez Gene)
Crkl
GeneProduct
287942 (Entrez Gene)
Dock1
GeneProduct
309081 (Entrez Gene)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
Elk1
GeneProduct
314436 (Entrez Gene)
Fos
GeneProduct
314322 (Entrez Gene)
Gab1
GeneProduct
361388 (Entrez Gene)
Grb2
GeneProduct
81504 (Entrez Gene)
Hgf
GeneProduct
24446 (Entrez Gene)
Hras
GeneProduct
293621 (Entrez Gene)
Itga1
GeneProduct
25118 (Entrez Gene)
Itgb1
GeneProduct
24511 (Entrez Gene)
Jun
GeneProduct
24516 (Entrez Gene)
Map2k1
GeneProduct
170851 (Entrez Gene)
Map2k2
GeneProduct
58960 (Entrez Gene)
Map4k1
GeneProduct
292763 (Entrez Gene)
Mapk1
GeneProduct
116590 (Entrez Gene)
Mapk3
GeneProduct
50689 (Entrez Gene)
Mapk8
GeneProduct
116554 (Entrez Gene)
Met
GeneProduct
24553 (Entrez Gene)
PIK3CA
GeneProduct
170911 (Entrez Gene)
Pak1
GeneProduct
29431 (Entrez Gene)
Pten
GeneProduct
50557 (Entrez Gene)
Ptk2
GeneProduct
25614 (Entrez Gene)
Ptk2b
GeneProduct
50646 (Entrez Gene)
Ptpn11
GeneProduct
25622 (Entrez Gene)
Pxn
GeneProduct
360820 (Entrez Gene)
RAPGEF1
GeneProduct
63881 (Entrez Gene)
Raf1
GeneProduct
24703 (Entrez Gene)
Rap1a
GeneProduct
295347 (Entrez Gene)
Rap1b
GeneProduct
171337 (Entrez Gene)
Rasa1
GeneProduct
25676 (Entrez Gene)
Sos1
GeneProduct
313845 (Entrez Gene)
Son of sevenless homolog 1 (Drosophila) (predicted)
Src
GeneProduct
83805 (Entrez Gene)
Stat3
GeneProduct
25125 (Entrez Gene)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions