Lipid metabolism in senescent cells (Homo sapiens)

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1Plasma membraneSASPSenescence-Associated Secretory PhenotypeCell cyclearrestCDKN1AHRASTP53ALOX5PUFAsPTGS2Lipid dropletsOxylipinSLCO2A1PLA2G1BFree PUFAsCytosolPTGS2Oxylipinbiosynthesis


Description

Description of the affected lipid metabolism in senecent cells.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wiley CD, Campisi J; ''The metabolic roots of senescence: mechanisms and opportunities for intervention.''; Nat Metab, 2021 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134714view12:29, 26 July 2024EweitzStandardize case, use singular
120374view20:35, 29 November 2021MkutmonOntology Term : 'cellular senescence pathway' added !
120372view20:34, 29 November 2021MkutmonOntology Term : 'lipid metabolic pathway' added !
120371view20:29, 29 November 2021Mkutmonadded subset PLA2 isozymes
120369view20:20, 29 November 2021MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ALOX5GeneProductENSG00000012779 (Ensembl)
CDKN1AGeneProductENSG00000124762 (Ensembl)
Cell cycle arrestPathway
Free PUFAsMetaboliteCHEBI:26208 (ChEBI)
HRASGeneProductENSG00000174775 (Ensembl)
Lipid dropletsQ573950 (Wikidata)
Oxylipin biosynthesisPathway
OxylipinMetaboliteCHEBI:61121 (ChEBI)
PLA2G1BGeneProductENSG00000170890 (Ensembl)
PTGS2GeneProductENSG00000073756 (Ensembl)
PUFAsMetaboliteCHEBI:26208 (ChEBI)
SLCO2A1GeneProductENSG00000174640 (Ensembl)
TP53GeneProductENSG00000141510 (Ensembl)

Annotated Interactions

No annotated interactions

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