N-glycan biosynthesis (Homo sapiens)

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2-411ER LumenMOGSMan-GDPDAD1PP-DolALG10STT3BFruc-6-PPolyprenolDOLPP1GlcNAc2Man6-PP-DolMPDU1RFT1ManB-P-DolDolicholGANABMAN1B1MGAT1MAN1A1MAN2A1MAN1A2MAN1C1MAN2A2MGAT2MGAT3FUT8B4GALT1B4GALT2B4GALT3ST6GAL1ST6GAL2Glc2GlcNAc2Man9-AsnGlcGlcNAc2Man9-AsnGlcNAc2Man9-AsnGlcNAc2Man8-AsnGlcNAc2Man5-AsnGlcNAc3Man5-AsnGlcNAc3Man3-AsnGlcNAc4Man3-AsnGlcNAc5Man3-AsnGlcNAc5Man3-AsnGlcNAc4LFucMan3-AsnMGAT5GlcNAc6Man3-AsnGlcNAc7Man3-AsnMGAT4CGal2GlcNAc4LFucMan3-AsnGal2GlcNAc4LFucMan3Neu5Ac2-AsnMGAT3ALG8ALG6ALG9ALG12ALG3GlcNAc2Man7-PP-DolGlcNAc2Man9-PP-DolGlcNAc2Man-PP-DolGlc2GlcNAc2Man9-PP-DolGlc2GlcNAc2Man9-PP-DolGlc3GlcNAc2Man9-PP-DolSTT3ADDOSTRPN1RPN2TUSC3Glc3GlcNAc2Man9-PP-DolGlc3GlcNAc2Man9AsnP-DolDOLKSRD5A3ALG7ALG13ALG14ALG1ALG2ALG11GlcNAc-PP-DolGlcNAc2PP-DolGlcNAc2ManPP-DolGlcNAc2Man2-PP-DolGlcNAc2Man3-PP-DolGlcNAc2Man5-PP-DolGlc3GlcNAc2Man9-PP-DolDPM1DPM2DPM3MPDU1GlcB-P-DolP-DolALG5P-DolGMPPAGMPPBPMM2MPIGPIGlc-6-PMan-6-PMan-1-PCytoplasmGolgiGlcNAc2Man8-AsnPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-DolPP-Dol


Description

draft

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''N-Glycan biosynthesis - Homo sapiens (human)''; https://www.kegg.jp/entry/pathway+hsa00510,
  2. Kranz C, Denecke J, Lehrman MA, Ray S, Kienz P, Kreissel G, Sagi D, Peter-Katalinic J, Freeze HH, Schmid T, Jackowski-Dohrmann S, Harms E, Marquardt T; ''A mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If).''; J Clin Invest, 2001 PubMed Europe PMC Scholia
  3. Varki A, Cummings RD, Esko JD, et al., editors; ''Essentials of Glycobiology [Internet]. 3rd edition.''; https://www.ncbi.nlm.nih.gov/books/NBK453020/, 2017 PubMed Europe PMC Scholia
  4. Dall'Olio F; ''Glycobiology of Aging.''; Subcell Biochem, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
127636view10:39, 11 November 2023EgonwAdded the identifier
127082view11:06, 30 July 2023EgonwModified description
126751view13:25, 18 June 2023EgonwAdded the chapter's PubMed ID.
125991view19:15, 23 March 2023KhanspersModified description
125990view18:58, 23 March 2023Khansperslatest - updated xrefs, labels
120567view20:42, 16 December 2021KhanspersOntology Term : 'protein modification pathway' added !
120566view20:42, 16 December 2021KhanspersOntology Term : 'N-linked glycan biosynthetic pathway' added !
120565view20:39, 16 December 2021KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ALG10GeneProductENSG00000139133 (Ensembl)
ALG11GeneProductENSG00000253710 (Ensembl)
ALG12GeneProductENSG00000182858 (Ensembl)
ALG13GeneProductENSG00000101901 (Ensembl)
ALG14GeneProductENSG00000172339 (Ensembl)
ALG1GeneProductENSG00000033011 (Ensembl)
ALG2GeneProductENSG00000119523 (Ensembl)
ALG3GeneProductENSG00000214160 (Ensembl)
ALG5GeneProductENSG00000120697 (Ensembl)
ALG6GeneProductENSG00000088035 (Ensembl)
ALG7GeneProductENSG00000172269 (Ensembl)
ALG8GeneProductENSG00000159063 (Ensembl)
ALG9GeneProductENSG00000086848 (Ensembl)
B4GALT1GeneProductENSG00000086062 (Ensembl)
B4GALT2GeneProductENSG00000117411 (Ensembl)
B4GALT3GeneProductENSG00000158850 (Ensembl)
DAD1GeneProductENSG00000129562 (Ensembl)
DDOSTGeneProductENSG00000244038 (Ensembl)
DOLKGeneProductENSG00000175283 (Ensembl)
DOLPP1GeneProductENSG00000167130 (Ensembl)
DPM1GeneProductENSG00000000419 (Ensembl)
DPM2GeneProductENSG00000136908 (Ensembl)
DPM3GeneProductENSG00000179085 (Ensembl)
DolicholMetaboliteCHEBI:88766 (ChEBI)
FUT8GeneProductENSG00000033170 (Ensembl)
Fruc-6-PMetaboliteCHEBI:16084 (ChEBI)
GANABGeneProductENSG00000089597 (Ensembl)
GMPPAGeneProductENSG00000144591 (Ensembl)
GMPPBGeneProductENSG00000173540 (Ensembl)
GPIGeneProductENSG00000105220 (Ensembl)
Gal2GlcNAc4LFucMan3-AsnMetaboliteG00017 (KEGG Glycan)
Gal2GlcNAc4LFucMan3Neu5Ac2-AsnMetaboliteG00018 (KEGG Glycan)
Glc-6-PMetaboliteHMDB0001401 (HMDB)
Glc2GlcNAc2Man9-AsnMetaboliteG00171 (KEGG Glycan)
Glc2GlcNAc2Man9-PP-DolMetaboliteG10598 (KEGG Glycan)
Glc2GlcNAc2Man9-PP-DolMetaboliteG10599 (KEGG Glycan)
Glc3GlcNAc2Man9-PP-DolMetaboliteG00006 (KEGG Glycan)
Glc3GlcNAc2Man9-PP-DolMetaboliteG00008 (KEGG Glycan)
Glc3GlcNAc2Man9AsnMetaboliteG00009 (KEGG Glycan)
GlcB-P-DolMetaboliteCHEBI:15812 (ChEBI)
GlcGlcNAc2Man9-AsnMetaboliteG00010 (KEGG Glycan)
GlcNAc-PP-DolMetaboliteG00001 (KEGG Glycan)
GlcNAc2Man-PP-DolMetaboliteG00007 (KEGG Glycan)
GlcNAc2Man2-PP-DolMetaboliteG00004 (KEGG Glycan)
GlcNAc2Man3-PP-DolMetaboliteG00005 (KEGG Glycan)
GlcNAc2Man5-AsnMetaboliteG00012 (KEGG Glycan)
GlcNAc2Man5-PP-DolMetaboliteG10526 (KEGG Glycan)
GlcNAc2Man6-PP-DolMetaboliteG10595 (KEGG Glycan)
GlcNAc2Man7-PP-DolMetaboliteG10596 (KEGG Glycan)
GlcNAc2Man8-AsnMetaboliteG10694 (KEGG Glycan)
GlcNAc2Man9-AsnMetaboliteG00011 (KEGG Glycan)
GlcNAc2Man9-PP-DolMetaboliteG10597 (KEGG Glycan)
GlcNAc2ManPP-DolMetaboliteG00003 (KEGG Glycan)
GlcNAc2PP-DolMetaboliteG00002 (KEGG Glycan)
GlcNAc3Man3-AsnMetaboliteG00014 (KEGG Glycan)
GlcNAc3Man5-AsnMetaboliteG00013 (KEGG Glycan)
GlcNAc4LFucMan3-AsnMetaboliteG00016 (KEGG Glycan)
GlcNAc4Man3-AsnMetaboliteG00015 (KEGG Glycan)
GlcNAc5Man3-AsnMetaboliteG00019 (KEGG Glycan)
GlcNAc5Man3-AsnMetaboliteG00020 (KEGG Glycan)
GlcNAc6Man3-AsnMetaboliteG00021 (KEGG Glycan)
GlcNAc7Man3-AsnMetaboliteG00022 (KEGG Glycan)
MAN1A1GeneProductENSG00000111885 (Ensembl)
MAN1A2GeneProductENSG00000198162 (Ensembl)
MAN1B1GeneProductENSG00000177239 (Ensembl)
MAN1C1GeneProductENSG00000117643 (Ensembl)
MAN2A1GeneProductENSG00000112893 (Ensembl)
MAN2A2GeneProductENSG00000196547 (Ensembl)
MGAT1GeneProductENSG00000131446 (Ensembl)
MGAT2GeneProductENSG00000168282 (Ensembl)
MGAT3GeneProductENSG00000128268 (Ensembl)
MGAT4CGeneProductENSG00000182050 (Ensembl)
MGAT5GeneProductENSG00000152127 (Ensembl)
MOGSGeneProductENSG00000115275 (Ensembl)
MPDU1GeneProductENSG00000129255 (Ensembl)
MPIGeneProductENSG00000178802 (Ensembl)
Man-1-PMetaboliteCHEBI:35374 (ChEBI)
Man-6-PMetaboliteCHEBI:48066 (ChEBI)
Man-GDPMetaboliteCHEBI:84880 (ChEBI)
ManB-P-DolMetaboliteHMDB00994 (HMDB)
P-DolMetaboliteCHEBI:16214 (ChEBI)
PMM2GeneProductENSG00000140650 (Ensembl)
PP-DolMetaboliteHMDB01513 (HMDB)
PolyprenolMetaboliteHMDB0004305 (HMDB)
RFT1GeneProductENSG00000163933 (Ensembl)
RPN1GeneProductENSG00000163902 (Ensembl)
RPN2GeneProductENSG00000118705 (Ensembl)
SRD5A3GeneProductENSG00000128039 (Ensembl)
ST6GAL1GeneProductENSG00000073849 (Ensembl)
ST6GAL2GeneProductENSG00000144057 (Ensembl)
STT3AGeneProductENSG00000134910 (Ensembl)
STT3BGeneProductENSG00000163527 (Ensembl)
TUSC3GeneProductENSG00000104723 (Ensembl)

Annotated Interactions

No annotated interactions

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